Navigation Links
Fighting bacteria with a new genre of antibodies
Date:4/24/2013

In an advance toward coping with bacteria that shrug off existing antibiotics and sterilization methods, scientists are reporting development of a new family of selective antimicrobial agents that do not rely on traditional antibiotics. Their report on these synthetic colloid particles, which can be custom-designed to recognize the shape of specific kinds of bacteria and inactivate them, appears in the Journal of the American Chemical Society.

Vesselin Paunov and colleagues point out that many bacteria have developed resistance to existing antibiotics. They sought a new approach one that bacteria would be unable to elude by mutating into drug-resistant forms. Their inspiration was the antibodies that the immune system produces when microbes invade the body. Those antibodies patrol the body for microbes and bind to their surfaces, triggering a chain of events in which the body's immune system attacks and destroys the microbes.

Paunov's team describes development and successful tests of synthetic colloid particles, called "colloid antibodies." Colloids are materials in which tiny particles of one material are dispersed in another material. Milk is a colloid in which globules of fat are spread throughout water and other materials. The colloid antibody particles are shells packed with a killing agent. They are designed to recognize and bind to specific bacteria.

Laboratory experiments showed that the colloid antibodies attached to and inactivated only their intended targets without harming other cells. "We anticipate that similar shape selective colloid antibodies can potentially become a powerful weapon in the fight against antibiotic-resistant bacteria," say the researchers. "They can also find applications as non-toxic antibacterial agents, preventing growth of harmful bacteria in various formulations."


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Fighting GM crop vandalism with a government-protected research site
2. Scientists find bone-marrow environment that helps produce infection-fighting T and B cells
3. Compound stimulates tumor-fighting protein in cancer therapy
4. University of Tennessee researchers find fungus has cancer-fighting power
5. Compound in grapes, red wine could be key to fighting prostate cancer
6. Fighting melanomas attraction to the brain
7. Research finds novel airborne germ-killing oral spray effective in fighting colds and flu
8. Nematodes with pest-fighting potential identified
9. Method to prevent rejection of disease-fighting proteins described in Human Gene Therapy journal
10. La Jolla institute identifies critical cell in fighting E. coli infection
11. UGA study reveals flu-fighting role for well-known immune component
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/26/2015)... TORONTO , March 26, 2015 ... premier family, social, recreation and athletic club, today announced ... designed to allow freedom of movement for members and ... "Following a comprehensive process, we selected FST,s IMID ... sophistication and convenience for our members and staff, in ...
(Date:3/24/2015)... 24, 2015   Crossmatch ™, a leading ... that its U.are.U ® 4500 Fingerprint Readers ... Bros . to achieve PCI compliance for Point-of-Sale ... to the POS terminal, protecting the retailer and ... breaches. With one-third of worldwide ...
(Date:3/23/2015)... Mar. 23, 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ... the growing mobile commerce market, announces its biometric payment technology, ... on CNBC television starting March 30 th . ... in New York markets. ... are excited about our new ad campaign following the recent ...
Breaking Biology News(10 mins):Granite Club First Private Club in North America to Implement FST Biometrics Secure Access Solution, as Part of Multi-million Dollar Expansion 2Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 2NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 3
... (ORI) scientists help young women reduce the influence of the ... with being thin. ORI scientist Eric Stice, Ph.D. ... reduced the risk for onset of eating disorders by 61% ... for as long as 3 years after the program ended. ...
... NEW YORK (APRIL 29, 2008) Bison can repopulate ... 100 years provided a series of conservation and restoration ... iconic species by the Wildlife Conservation Society and other ... group of conservationists, scientists, ranchers, and Native Americans/First Nations ...
... responsible for the deadly food poisoning disease botulism and ... can also be used as a dreaded biological ... of an ounce can cause muscle paralysis and eventual ... inhibit the destructive action of this neurotoxin the ...
Cached Biology News:Body image program reduces onset of obesity and eating disorders 2Bison can thrive again, study says 2Scientists determine drug target for the most potent botulinum neurotoxin 2
(Date:5/5/2015)... NEW YORK , May 5, 2015 /PRNewswire/ ... today announced that Andrew Gengos , President and ... on May 7, 2015. DATE:  Thursday, May ... LINK:  http://VirtualInvestorConferences.com > click the ... will be a live, interactive online event where ...
(Date:5/5/2015)... Franz Inc ., the leading supplier of ... product, AllegroGraph, has been named a Champion by Bloor Research ... AllegroGraph is a high performance Semantic Graph Database that ... are skyrocketing in popularity and have grown by 400% in ... ranking by DB-Engines. , “We are excited that Graph ...
(Date:5/5/2015)... May 5, 2015 CytomX, a biotechnology company ... announced that Sean McCarthy , D. Phil., chief ... Day in New York at ... will present an overview of CytomX,s Probody pipeline, including ... programs. About CytomX Therapeutics CytomX Therapeutics ...
(Date:5/5/2015)... Hills, MI (PRWEB) May 05, 2015 ... premier Parker Hannifin distributor, announces the launch of ... provide fleet operators with a convenient way to ... maintenance products . , The new ... to 100,000 vehicles with direct access to high ...
Breaking Biology Technology:ImmunoCellular Therapeutics to Webcast Live at VirtualInvestorConferences.com on May 7 2Bloor Research Positions AllegroGraph as a ‘Champion’ in Burgeoning Graph Database Market 2Bloor Research Positions AllegroGraph as a ‘Champion’ in Burgeoning Graph Database Market 3Exotic Automation & Supply Launches Ecommerce Website 2
... Klein: The Wisconsin Alumni Research Foundation will receive a ... transfer. Wingra Technologies has been acquired by a west-coast ... posted improved financial results for the past fiscal year. Original air ... episode Read more about Wingra being ...
... drives business. Whoa! Put down those pitchforks and torches! ... start some kind of technology for technology's sake argument here. ... in the business of building and selling technology should head ... years as wave after wave of technology has washed across ...
... , a provider of health-care and business technology, announced a ... new Medicaid Management Information System (MMIS). The new system is ... announced in November, contracts EDS to implement its InterChange health ... Health and Family Services . The contract is worth approximately ...
Cached Biology Technology:Stay in the driver's seat, but don't ditch technology 2Stay in the driver's seat, but don't ditch technology 3State picks long-time vendor for $189m Medicaid information system 2
6-keto Prostaglandin F1α EIA Antiserum 6-keto-PGF1alpha EIAs prostaglandins antisera enzyme immunoassays reagents 6-keto-PGF1.alpha....
... reagent has been developed for use ... reduction of nonspecific background staining due ... describe blocking peroxidase with hydrogen peroxide. ... in combination with additional novel components ...
Phospho-Btk (Tyr223) Antibody...
Rad51B...
Biology Products: