Navigation Links
Fighting antibiotic resistance with 'molecular drill bits'
Date:3/17/2014

DALLAS, March 17, 2014 In response to drug-resistant "superbugs" that send millions of people to hospitals around the world, scientists are building tiny, "molecular drill bits" that kill bacteria by bursting through their protective cell walls. They presented some of the latest developments on these drill bits, better known to scientists as antimicrobial peptides (AMPs), at the 247th National Meeting & Exposition of the American Chemical Society (ACS), the world's largest scientific society.

The meeting, which features more than 10,000 scientific reports across disciplines from energy to medicine, continues here through Thursday.

One of the researchers in the search for new ways to beat pathogenic bacteria is Georges Belfort, Ph.D. He and his team have been searching for a new therapy against the bacteria that cause tuberculosis (TB). It's a well-known, treatable disease, but resistant strains are cropping up. The World Health Organization estimates that about 170,000 people died from multidrug-resistant TB in 2012.

"If the bacteria build resistance to all current treatments, you're dead in the water," said Belfort, who is at Rensselaer Polytechnic Institute.

To avoid this dire scenario, scientists are developing creative ways to battle the disease. In ongoing research, Belfort's group together with his wife, Marlene Belfort, and her group at the University at Albany are trying to dismantle bacteria from within. They also decided to attack it from the outside.

In their search for a way to do this, they came upon AMPs. Although these naturally occurring, short strings of amino acids are not new all classes of organisms from humans to bacteria produce them as part of their natural defense strategy the fight against drug-resistant pathogens has heightened attention on these protective molecules.

Researchers began studying them in earnest in the 1980s. By 2010, they had identified nearly 1,000 unique AMP
'/>"/>

Contact: Michael Bernstein
214-853-8005 (Dallas Press Center, March 14-19)
202-872-6042
m_bernstein@acs.org

Contact: Katie Cottingham, Ph.D.
214-853-8005 (Dallas Press Center, March 14-19)
301-775-8455
k_cottingham@acs.org

American Chemical Society


Source:Eurekalert

Page: 1 2

Related biology news :

1. Preventing home invasions means fighting side-by-side for coral-dwelling crabs and shrimp
2. Study finds cancer-fighting goodness in cholesterol
3. Trial launched into curry chemicals cancer-fighting properties
4. Canadian girl, 16, invents disease-fighting, anti-aging compound using tree particles
5. Fighting bacterias strength in numbers
6. UGA study reveals flu-fighting role for well-known immune component
7. La Jolla institute identifies critical cell in fighting E. coli infection
8. Method to prevent rejection of disease-fighting proteins described in Human Gene Therapy journal
9. Nematodes with pest-fighting potential identified
10. Research finds novel airborne germ-killing oral spray effective in fighting colds and flu
11. Fighting melanomas attraction to the brain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/15/2014)... , Nov. 13, 2014  While we may still ... Doctor McCoy used in "Star Trek" to gain instant access ... designed to work with smartphones and tablets for monitoring and ... the healthcare world. This may seem a tad Orwellian to ... to adopt some of these technological opportunities into their healthcare ...
(Date:11/11/2014)... , Nov. 11, 2014  Forensicon, Inc., a ... is pleased to announce the promotion of Yaniv ... of Digital Forensics. In Schiff,s new role as Director, ... team of digital forensics examiners and provide leadership within ... Photo - http://photos.prnewswire.com/prnh/20141110/157719 Schiff ...
(Date:11/7/2014)... by Dr. Debra Auguste, associate professor, biomedical engineering, ... City College of New York, have identified a ... one of the most aggressive forms of breast ... a high mortality rate owing to aggressive proliferation ... options. However, Professor Auguste,s team, discovered the overexpression ...
Breaking Biology News(10 mins):Americans May Be Ready for a Brave New World of Healthcare 2Americans May Be Ready for a Brave New World of Healthcare 3Americans May Be Ready for a Brave New World of Healthcare 4Yaniv Schiff Promoted to Director of Digital Forensics at Forensicon, Inc. 2
... (February 6, 2008) Consumers have long known ... healthy bones and even help promote weight loss. However, ... the Journal of Periodontology, the official publication of the ... of dairy products may also help promote periodontal health. ...
... Calif., Feb. 6, 2008 A study by UC ... boosts plant growth by an average of 20 percent, ... to nitrogen pollution. Faster plant growth means the ... thought, though long-term climate effects are unclear. Over the ...
... this week,s issue of "New Scientist" magazine, research by Rice ... is on one,s mind about politics may be influenced by ... this topic for a number of years, and his team ... in the United States and supplemented it with findings from ...
Cached Biology News:Want healthy gums? Hit the dairy aisle 2Nitrogen pollution boosts plant growth in tropics by 20 percent 2
(Date:11/22/2014)... November 21, 2014 On November 17th ... the 2014 Emerging Medical Technologies Summit in San Francisco ... Widely regarded among Silicon Valley investors and technology ... innovation, the win also positions Briteseed to move ... competition in 2015 and compete with other elite innovation ...
(Date:11/22/2014)... --   , ... KLOX    Mariano Rodriguez ... bestellt    KLOX ist bestens vorbereitet, ... Behandlungssystems zur Wundheilung zu beginnen    , ... erfreut, die folgenden personellen Veränderungen anzukündigen: ...
(Date:11/21/2014)... November 20, 2014 Offering a complete ... Sartorius Entris Balance promotion . The Sartorius Entris Balance ... durable, high accuracy, and easy-to-maintain balance entry level balance. ... It was designed to help customer’s bridge the gap ... balance that is very durable. Sartorius is the second ...
(Date:11/21/2014)... The November 2014 issue of BioTechniques ... access journal featuring the following articles:, , ... photoresponsiveness in the retina , DNA from ... using chromogenic substrates in zebrafish , Re-use ... electrophoresis , Nuclear LC3-positive puncta in stressed ...
Breaking Biology Technology:Insight Product Development Accelerator Member Wins MedTech Innovator Award Competition 2Insight Product Development Accelerator Member Wins MedTech Innovator Award Competition 3KLOX Technologies meldet Neubesetzung von Führungspositionen 2KLOX Technologies meldet Neubesetzung von Führungspositionen 3KLOX Technologies meldet Neubesetzung von Führungspositionen 4KLOX Technologies meldet Neubesetzung von Führungspositionen 5Pipette.com Announces an Extension on the Sartorius Entris Balance Promotion to the End of 2014 2BioTechniques: The International Journal of Life Science Methods Announces the Publication of the November 2014 Issue—Available in Print and Online 2BioTechniques: The International Journal of Life Science Methods Announces the Publication of the November 2014 Issue—Available in Print and Online 3
... BEIJING, Nov. 13 /PRNewswire-Asia/ -- IVT Corporation announced today ... Mobile Asia Congress,in Hong Kong on Nov. 18-19, at Booth ... monitoring from home, reducing risk of diseases and,assisting with emergency ... ) , It includes: , ...
... An experiment by college students that will study how ... shuttle Atlantis. , (Logo: http://www.newscom.com/cgi-bin/prnh/20081007/38461LOGO ) ... in Houston developed the experiment that will fly as part ... at 2:28 p.m. EST on Nov. 16 from NASA,s Kennedy ...
... ... addresses common problems associated with purification of recombinant proteins by enabling the delivery ... ... (PRWEB) November 12, 2009 -- The recently released Promega HaloTag® Protein Purification System ...
Cached Biology Technology:IVT will Demo Mobile Health System at GSMA Mobile Asia Congress and CES 2010 2Students Send Microbe Experiment on Space Shuttle Atlantis 2Students Send Microbe Experiment on Space Shuttle Atlantis 3Promega HaloTag Protein Purification System Makes it Easier to Purify Difficult-to-Express Proteins 2
... screen, without Camera • ... mega pixel resolution. It is computer free for ... from large 5.6" TFT color liquid crystal display ... capture image for fluorescent gels, colorimetric gels, auto ...
... The binding specificity and signaling of the ... to be modified by alternative splicing--which has ... SpliceArrays you can perform a classical expression ... the different alternatively spliced forms of the ...
Mouse monoclonal antibody raised against a full length recombinant CSNK2A2. NCBI Entrez Gene ID = CSNK2A2...
... Apoptosis is an evolutionarily conserved form of ... process. The central component of this ... called caspases. These enzymes participate in ... in response to pro-apoptotic signals and result ...
Biology Products: