Navigation Links
Fetus suffers when mother lacks vitamin C
Date:11/16/2012

Maternal vitamin C deficiency during pregnancy can have serious consequences for the foetal brain. And once brain damage has occurred, it cannot be reversed by vitamin C supplements after birth. This is shown through new research at the University of Copenhagen just published in the scientific journal PLOS ONE.

Population studies show that between 10-20 per cent of all adults in the developed world suffer from vitamin C deficiency. Therefore, pregnant women should think twice about omitting the daily vitamin pill.

"Even marginal vitamin C deficiency in the mother stunts the foetal hippocampus, the important memory centre, by 10-15 per cent, preventing the brain from optimal development," says Professor Jens Lykkesfeldt. He heads the group of scientists that reached this conclusion by studying pregnant guinea pigs and their pups. Just like humans, guinea pigs cannot produce vitamin C themselves, which is why they were chosen as the model.

"We used to think that the mother could protect the baby. Ordinarily there is a selective transport from mother to foetus of the substances the baby needs during pregnancy. However, it now appears that the transport is not sufficient in the case of vitamin C deficiency. Therefore it is extremely important to draw attention to this problem, which potentially can have serious consequences for the children affected," says Jens Lykkesfeldt.

Too late when damage is done

The new results sharpen the focus on the mother's lifestyle and nutritional status during pregnancy. The new study has also shown that the damage done to the foetal brain cannot be repaired, even if the baby is given vitamin C after birth.

When the vitamin C deficient guinea pig pups were born, scientists divided them into two groups and gave one group vitamin C supplements. However, when the pups were two months old, which corresponds to teenage in humans, there was still no improvement in the group that had been given supplements.

The scientists are now working to find out how early in the pregnancy vitamin C deficiency influences the development of foetal guinea pigs. Preliminary results show that the impact is already made early in the pregnancy, as the foetuses were examined in the second and third trimesters. Scientists hope in the long term to be able to use population studies to illuminate the problem in humans.

Vulnerable groups

There are some groups that may be particularly vulnerable of vitamin C deficiency:

"People with low economic status who eat poorly - and perhaps also smoke - often suffer from vitamin C deficiency. Comparatively speaking, their children risk being born with a poorly developed memory potential. These children may encounter learning problems, and seen in a societal context, history repeats itself because these children find it more difficult to escape the environment into which they are born," says Jens Lykkesfeldt.

He emphasises that if pregnant women eat a varied diet, do not smoke, and for instance take a multi-vitamin tablet daily during pregnancy, there is no reason to fear vitamin C deficiency.

"Because it takes so little to avoid vitamin C deficiency, it is my hope that both politicians and the authorities will become aware that this can be a potential problem," concludes Jens Lykkesfeldt.


'/>"/>

Contact: Professor Jens Lykkesfeldt
jopl@sund.ku.dk
45-35-33-31-25
University of Copenhagen
Source:Eurekalert

Related biology news :

1. Highly exposed to phthalates as fetuses, female mice have altered reproductive lives
2. Smallest and largest fetuses at greater risk of being stillborn, research finds
3. Foetus suffers when mother lacks vitamin C
4. 15-year study: When it comes to creating wetlands, Mother Nature is in charge
5. Montreal researchers repel mortality in Malian mothers
6. Harmless human virus may be able to boost the effects of chemotherapy
7. Nanobubbles plus chemotherapy equals single-cell cancer targeting
8. First ever videos of snow leopard mother and cubs in dens recorded in Mongolia
9. New biomarker for common lung cancer predicts responses to chemotherapy
10. Infants of overweight mothers grow more slowly
11. Scientists uncover strategy able to dramatically reduce chemotherapys side effects
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2017)... 2017 RAM Group , Singaporean ... breakthrough in biometric authentication based on a ... to perform biometric authentication. These new sensors are based ... by Ram Group and its partners. This sensor will ... chains and security. Ram Group is a next ...
(Date:4/19/2017)... York , April 19, 2017 ... as its vendor landscape is marked by the presence ... market is however held by five major players - ... Together these companies accounted for nearly 61% of the ... the leading companies in the global military biometrics market ...
(Date:4/17/2017)... MELBOURNE, Florida , April 17, 2017 ... security technology company, announces the filing of its 2016 Annual Report ... Securities and Exchange Commission. ... Report on Form 10-K is available in the Investor Relations section ... well as on the SEC,s website at http://www.sec.gov . ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... launched Rosalind™, the first-ever genomics analysis platform specifically designed for life science ... in honor of pioneering researcher Rosalind Franklin, who made a major contribution ...
(Date:10/11/2017)... ... October 11, 2017 , ... The CRISPR-Cas9 ... overexpression experiments and avoiding the use of exogenous expression plasmids. The simplicity of ... performing systematic gain-of-function studies. , This complement to loss-of-function studies, such as ...
(Date:10/11/2017)... ... October 11, 2017 , ... ComplianceOnline’s Medical Device Summit is back for its ... 2018 in San Francisco, CA. The Summit brings together current and former FDA office ... directors and government officials from around the world to address key issues in device ...
(Date:10/11/2017)... BioMarketing, a leading provider of patient support solutions, has announced ... network, which will launch this week. The VMS CNEs will ... to enhance the patient care experience by delivering peer-to-peer education ... professionals to help women who have been diagnosed and are ... ...
Breaking Biology Technology: