Navigation Links
Fetal alcohol syndrome testing expands
Date:3/19/2009

Kingston, ON Improved technology, partnerships and collaboration across two provinces have allowed Queen's University scientists to dramatically expand the use of eye-movement tests that help identify and assess children with Fetal Alcohol Spectrum Disorder (FASD).

"Our initial study was carried out with a relatively small group of children who had to travel to Queen's to participate in the experiment," notes Pharmacology and Toxicology professor James Reynolds, who leads the project. "Establishing a mobile laboratory allowed us to go where the kids are, and carry out these experiments in community settings."

Thanks to the cooperation of local health professionals and community members, the researchers tested more than 200 children in nine different Ontario and Alberta locations.

"Now we know that the results of eye movement testing are consistent across different geographical locations something that is absolutely critical if this type of testing is to be widely applicable," says Dr. Reynolds.

Until now, there have been few objective tools that will accurately measure brain function in young children. This breakthrough will add eye movement testing to the standard clinical assessment protocols currently in use, to determine the potential for identifying at-risk children.

The work was sponsored by the Canadian Institutes of Health Research (CIHR) as part of a multi-university New Emerging Team project. The findings are highlighted today in an on-line article in the European Journal of Neuroscience.

"This is a most original finding, with clear clinical application," says Dr. Rmi Quirion, Scientific Director of the CIHR Institute of Neurosciences, Mental Health and Addiction. "Fetal Alcohol Spectrum Disorder is a significant health issue in Canada. The work of Dr Reynolds and his team is an excellent example of what CIHR aims for: improving the health of Canadians through cutting-edge, innovative research."

The Queen's researchers are continuing to develop novel approaches for using eye movements to assess brain function. In collaboration with Doug Munoz, director of Queen's Centre for Neuroscience Studies, they are using the university's functional MRI (magnetic resonance imaging) facility to measure differences in brain activity in children with developmental disorders such as FASD and ADHD (Attention Deficit Hyperactivity Disorder). They are building a database of task performance and brain functioning across many clinical populations.

"This is very exciting because it points us toward using eye movements to show differences in clinical populations," says Dr. Reynolds. "Once we understand what 'typical' development looks like, we can use the same tools to identify signature characteristics of each of the disorders."

Defined as birth defects resulting from a mother's consumption of alcohol during pregnancy, FASD is believed to affect approximately one per cent of children in Canada. FASD is associated with hyperactivity, difficulty in learning, and deficits in memory, understanding and reasoning, as well as problems dealing with stress.

In the absence of confirmed maternal alcohol consumption during pregnancy, the diagnosis of FASD remains a significant clinical challenge. "The ability to objectively assess brain function at earlier and earlier ages will be hugely beneficial in the long term, because it will help identify the at-risk children for whom targeted interventions will have the greatest impact," says Dr. Reynolds.


'/>"/>

Contact: Nancy Dorrance
nancy.dorrance@queensu.a
613-533-2869
Queen's University
Source:Eurekalert  

Related biology news :

1. Chicks to give scientists clearer picture of fetal development
2. Alcohol consumption can cause too much cell death, fetal abnormalities
3. Researchers block damage to fetal brain following maternal alcohol consumption
4. New study shows that fetal cells to treat Parkinsons disease may not function long term
5. Study suggests new way to screen infants for fetal alcohol syndrome
6. Study reveals possible genetic risk for fetal alcohol disorders
7. AJCN study shows moderate alcohol consumption related to stronger bones
8. Moderate alcohol intake associated with bone protection
9. Alcohol: A life sentence
10. Resveratrol prevents fat accumulation in livers of alcoholic mice
11. Alcohol binges early in pregnancy increase risk of infant oral clefts
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Fetal alcohol syndrome testing expands
(Date:3/22/2016)... March 22, 2016 ... Sensors Market for Consumer Industry by Type (Image, ... Application (Communication & IT, Entertainment, Home Appliances, ... Forecast to 2022", published by MarketsandMarkets, the ... to reach USD 26.76 Billion by 2022, ...
(Date:3/15/2016)... -- --> --> According ... "Digital Door Lock Systems Market - Global Industry Analysis, Size, ... digital door lock systems market in terms of revenue was ... to grow at a CAGR of 31.8% during the period ... (MSMEs) across the world and high industrial activity driving inclusive ...
(Date:3/11/2016)... PUNE, India , March 11, 2016 ... to a new market research report "Image Recognition Market ... by Application (Marketing and Advertising), by Deployment Type (On-Premises ... Global Forecast To 2022", published by MarketsandMarkets, the global ... in 2015 to USD 29.98 Billion by 2020, at ...
Breaking Biology News(10 mins):
(Date:5/25/2016)... ... May 25, 2016 , ... ... and Drug Administration (FDA) has granted the company’s orphan drug designation request covering ... orphan drug designation granted by the FDA. , Spinocerebellar ataxia is a ...
(Date:5/24/2016)... , ... May 24, 2016 , ... Last week, Callan ... corporate executives and entrepreneurs, held The Future of San Diego Life Science event at ... Diego life science community attended the event with speakers Dr. Rich Heyman, former CEO ...
(Date:5/23/2016)... ... 23, 2016 , ... PrecisionAg® Media has released its latest ... The paper outlines the key trends that are creating both opportunities and challenges ... lot of highs and lows as the precision agriculture market has grown and ...
(Date:5/23/2016)... and LONDON , May 23, 2016 /PRNewswire/ ... See Frontage Boost Efficiency by 40% - Frontage Implement ... - Frontage Enforce Quality, Compliance and Traceability Within the Bioanalytical lab ... labs in the United States and ... to be deployed across its laboratory facilities. In addition to serving ...
Breaking Biology Technology: