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Female human embryos adjust the balance of X chromosomes before implantation
Date:6/29/2009

that expected. If they are not fully undifferentiated, then they might be unable to transform completely into the particular tissues that researchers might be trying to create in the laboratory for therapeutic purposes.

"If the current human ES cell lines are in fact isolated too early, before X chromosome reactivation happens in the human blastocyst, then alternative strategies for generating human ES cell lines need to be developed. Obviously, an important step is to investigate exactly when and how reactivation of the X chromosome happens in the human embryo and to use this information in the derivation of new human ES cell lines. We are planning further research to clarify these issues," concluded Ms van den Berg.


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Contact: Mary Rice
mary@mrcommunication.org
European Society for Human Reproduction and Embryology
Source:Eurekalert

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