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February 2009 highlights from Biology of Reproduction
Date:1/20/2009

fspring from the elderly males exhibit abnormalities not only in several behavioral traits, but also in reproductive fitness and longevity. The early death of offspring sired by old mice was heralded by rapid weight loss. Moreover, mating the offspring derived from aged males resulted in the production of pups exhibiting decreased weights at weaning when compared with pups from the offspring of younger males: an apparent transgenerational effect. The defects causing the abnormalities in offspring are unknown and should be the objective of intriguing studies in the future.

Silvia Garca-Palomares, Jos F. Pertusa, Jos Mi arro, Miguel A. Garca-Prez, Carlos Hermenegildo, Francisco Rausell, Antonio Cano, and Juan J. Tarn. Long-Term Effects of Delayed Fatherhood in Mice on Postnatal Development and Behavioral Traits of Offspring. Biol Reprod 2009; 337-342. Published in BOR-Papers in Press 15 October 2008; DOI: 10.1095/biolreprod.108.072066

Silvia Garca-Palomares, Samuel Navarro, Jos F. Pertusa, Carlos Hermenegildo, Miguel A. Garca-Prez, Francisco Rausell, Antonio Cano, and Juan J. Tarn. Delayed Fatherhood in Mice Decreases Reproductive Fitness and Longevity of Offspring. Biol Reprod 2009; 343-349. Published in BOR-Papers in Press 15 October 2008; DOI: 10.1095/biolreprod.108.073395


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Contact: Judith Jansen
ssradmin@ssr.org
608-256-2777
Society for the Study of Reproduction
Source:Eurekalert

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