Navigation Links
Fatty acids involved in python heart growth could benefit diseased human heart
Date:10/27/2011

TUSCALOOSA, Ala. Identification of three fatty acids involved in the extreme growth of Burmese pythons' hearts following large meals could prove beneficial in treating diseased human hearts, according to research co-authored by a University of Alabama scientist and publishing in the Oct. 28 issue of Science.

Growth of the human heart can be beneficial when resulting from exercise a type of growth known as physiological cardiac hypertrophy but damaging when triggered by disease growth known as pathological hypertrophy. The new research shows a potential avenue by which to make the unhealthy heart growth more like the healthy version.

"We may later be able to turn the tables, in a sense, in the processes involved in pathological hypertrophy by administering a combination of fatty acids that occur in very high concentrations in the blood of digesting pythons," said Dr. Stephen Secor, associate professor of biological sciences at UA and one of the paper's co-authors. "This could trigger, perhaps, something more akin to the physiological form of hypertrophy."

The research, conducted in collaboration with multiple researchers at the University of Colorado working in the lab of Dr. Leslie Leinwand, identified three fatty acids, myristic acid, palmitic acid and palmitoleic acid, for their roles in the snakes' healthy heart growths following a meal.

Researchers took these fatty acids from feasting pythons and infused them into fasting pythons. Afterward, those fasting pythons underwent heart-rate growths similar to that of the feasting pythons. In a similar fashion, the researchers were able to induce comparable heart-rate growths in rats, indicating that the fatty acids have a similar effect on the mammalian heart.

The paper, whose lead author was Dr. Cecilia Riquelme of the University of Colorado, also showed that the pythons' heart growth was a result of the indi
'/>"/>

Contact: Chris Bryant
cbryant@ur.ua.edu
205-348-8323
University of Alabama in Tuscaloosa
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related biology news :

1. Liver parasite lacks key genes for fatty acid synthesis: Genome sequencing of Clonorchis sinensis
2. How fatty diets cause diabetes
3. Gene variant increases fatty liver risk and fibrosis progression
4. Scientists develop a fatty kryptonite to defeat multidrug-resistant Super bugs
5. Fish livers contain beneficial fatty acids
6. New data show non-alcoholic fatty liver disease will reach epidemic status in the US
7. New sleep cycle discovery explains why fatty diets during pregnancy make kids obese
8. Consuming polyunsaturated fatty acids may lower the incidence of gum disease
9. U of I study: Lack of omega-3 fatty acid linked to male infertility
10. U of I study: Lack of omega-6 fatty acid linked to severe dermatitis
11. How much omega-3 fatty acid do we need to prevent cardiovascular disease?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2013)... COLUMBUS, Ohio New research suggests that a compound ... "superpower" to escape death. , By altering a ... re-educates cancer cells into normal cells that die as ... by inhibiting a process that would cause them to ... strict programming. This study in cells, led by Ohio ...
(Date:5/20/2013)... A novel vaccine study from South Dakota State ... be unveiled at the American Association of Pharmaceutical Scientists, ... Monday, May 20 - Wednesday, May 22 at the ... main goal of a vaccine is to stimulate the ... the disease", explained Dr. Hemachand Tummala, assistant professor of ...
(Date:5/20/2013)... Colo., USA New Geology articles ... May 2013 cover a wide swath of geoscience ... oceanography, geophysics, and paleobotany. Locations studied include Siberia; ... at Alpi Apuane, Italy; Ukraine; Mars; and the ... , 1. Rubies, jadeite, and plate tectonics;, 2. ...
Breaking Biology News(10 mins):The compound in the Mediterranean diet that makes cancer cells 'mortal' 2The compound in the Mediterranean diet that makes cancer cells 'mortal' 3Germ-fighting vaccine system makes great strides in delivery 2New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 2New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 3New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 4New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 5New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 6New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 7New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 8New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 9New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 10New in GEOLOGY: Gems, Darwin, Mars, Hemp, Snowball Earth, a Siberian Impact Crater, and More 11
... by the National Institute of Dental and Craniofacial Research ... added a key new piece to the puzzle of ... and fuel their abnormal growth, a well-known process called ... the journal Cancer Cell, the scientists found that in ...
... obstacles in their physical environments and must engage appropriate ... these obstacles can involve highly complex events in mammals ... employed an ingenious obstacle-based system for studying the control ... fly Drosophila. , The findings are reported in ...
... (NIH) today announced it is awarding $88.9 million in ... a collaborative research network that will use high-tech screening ... as research tools. Small molecules have great potential to ... key biological processes involved in human health and disease. ...
Cached Biology News:New lead reported in tumor angiogenesis 2New lead reported in tumor angiogenesis 3Gap-climbing fruit flies reveal components of goal-driven behaviors 2NIH creates nationwide network of molecular libraries screening centers 2NIH creates nationwide network of molecular libraries screening centers 3
(Date:5/20/2013)... 20, 2013 Oven Industries Inc. announces ... capabilities. The 5R6-900 benchtop controller has many outstanding user-friendly ... be plugged into the wall as a self-contained temperature ... distinctive detail makes the device unique, as well as ... temperature controller can also be used universally, which allows ...
(Date:5/20/2013)... -- Dr. Gerald Zon , noted scientist ... a new blog in conjunction with TriLink BioTechnologies. The ... on what,s trending in the field of nucleic acids. ... of research presented at conferences and meetings, reviews of ... (PhD Princeton University 1971) developed automated synthesis of DNA ...
(Date:5/20/2013)... 20, 2013 Cempra, Inc. (Nasdaq: CEMP), ... antibiotics to meet critical medical needs in the ... presented data at the American Thoracic Society International ... demonstrating the antibacterial and enhanced immunomodulatory activity ... 2 clinical trial in outpatients with community acquired ...
(Date:5/20/2013)... Researchers from the Southern University of Denmark ... and the acne causing P.acnes bacteria. Researchers believe found that ... out oxygen deprived location to seek shelter and grow. When ... the ability to live in the open joint areas, causing ... “ The best acne treatment ” explains why starting a ...
Breaking Biology Technology:New Laboratory Temperature Controller by Oven Industries 2Dr. Gerald 'Jerry' Zon Launches New Blog for TriLink BioTechnologies 2Cempra Presents Post-Phase 2 Analysis of Solithromycin's Efficacy and Safety Results from Patients with Community Acquired Bacterial Pneumonia (CABP) 2Adult Acne Treatment, Probiotic Action Shares New Insight How Treating Acne May Help Reduce Body Pain 2
... to the development and use of devices that are ... in importance as a science, and the term now ... are less than 1,000 nanometers of the substances involved ... catalyst in the creation of exciting and innovative new ...
... used for labs, technology, research, communication and planning ... announced that the Department of Health and Human Services ... the capacity of states, territories and metro areas to ... is scheduled to receive $25 million, of which almost ...
... is like giving out your phone number on a blind ... Sometimes you never hear from them again. And, sometimes they ... date from hell. You are deluged by a rapid array ... fast, reliable, and inexpensive their products are. They talk, talk ...
Cached Biology Technology:Nanotechnology - Natures Lego Blocks! 2Wisconsin to Receive $25 Million for Bioterrorism 2Quantity versus Quality: Effective E-Marketing Relationships 2Quantity versus Quality: Effective E-Marketing Relationships 3
... DNA Engine instrument is the cycler ... Unprecedented thermal uniformity and swappable blocks ... This rugged machine is ... a platform for new features and ...
... Array (MSTA) slides were designed to study protein ... multiple species. Tissue slices from three different ... can then be treated as a single histological ... situ hybridization. This format allows a ...
... Clear yellow solution. In ... thimerosal, and other proprietary ... Diluent formulated to stabilize ... antibody conjugates at high ...
... WinMelt software is used ... of any DNA sequence up ... in optimizing placement of primers ... detection by denaturing gradient gel ...
Biology Products: