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Fat stem cells safe for breast reconstruction when cancer is dormant, says Pitt team
Date:9/16/2010

lls. The combination of active tumor cells and ADSC led to dramatic tumor growth, while injections of resting tumor cells were not affected by co-injection of either ADSC or irradiated tumor cells.

"There is already some clinical evidence that breast reconstruction with transplanted fat is safe. Our findings lead us to conclude that augmentation of fat grafts with additional ADSC should be postponed until there is no evidence of active cancer," Dr. Donnenberg said. "Our data in the mouse suggest that dormant cancer cells are not sensitive to the growth signals sent by the ADSC."


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Contact: Anita Srikameswaran
SrikamAV@upmc.edu
412-578-9193
University of Pittsburgh Schools of the Health Sciences
Source:Eurekalert

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