Navigation Links
Faster anthrax detection could speed bioterror response
Date:2/27/2014

COLUMBIA, Mo. Shortly following the 9/11 terror attack in 2001, letters containing anthrax spores were mailed to news outlets and government buildings killing five people and infecting 17 others. According to a 2012 report, the bioterrorism event cost $3.2 million in cleanup and decontamination. At the time, no testing system was in place that officials could use to screen the letters. Currently, first responders have tests that can provide a screen for dangerous materials in about 24-48 hours. Now, researchers at the University of Missouri have worked with a private company to develop a new method for anthrax detection that can identify anthrax in only a few hours.

"Normally to identify whether an organism is present, you have to extract the material, culture it, and then pick colonies to examine that might turn out to be anthrax bacteria," said George Stewart, PhD, a medical bacteriologist at MU's Bond Life Sciences Center and chairman of the Department of Veterinary Pathobiology and McKee Endowed Professor within the MU College of Veterinary Medicine. "Then you conduct chemical testing which takes some time-a minimum of 24 to 48 hours. Using this newly-identified method, we can reduce that time to about five hours."

Using a virus known as a "bioluminescent reporter phage," Stewart and graduate student, Krista Spreng, tested the phage at the MU Laboratory for Infectious Disease Research. The phage, developed by David Schofield at Guild BioSciences, a biotech company in Charleston, S.C., is injected in the sample causing anthrax to glow if present. The team also found that the method can detect low levels of anthrax bacteria and rule out false positives. The added benefit to this reporting system is its ability to show if anthrax is present and whether or not the spores are alive, Stewart said.

The next step for the research team at MU and Guild BioSciences will be to get the bioluminescent reporter phage approved by federal regulatory agencies so a product can be produced and distributed, Stewart said.

"In the years since the post 9/11 postal attacks, we haven't had any bona fide anthrax attacks," Stewart said. "That doesn't mean that it's not going to happen, we just have to be prepared for when it does occur again."

The research, "Bacillus anthracis diagnostic detection and rapid antibiotic susceptibility determination using 'bioluminescent' reporter phage," was funded by the USDA and published in the Journal of Microbiological Methods.


'/>"/>

Contact: Jeff Sossamon
sossamonj@missouri.edu
573-882-3346
University of Missouri-Columbia
Source:Eurekalert  

Related biology news :

1. A faster way to flag bacteria-tainted food -- and prevent illness
2. Faster testing of new pharmaceuticals
3. The bigger the tree, the faster it grows
4. Trees grow faster and store more carbon as they age
5. EU policy is driving up demand for pollination faster than honeybee numbers
6. Ultrafast heating of water -- This pot boils faster than you can watch it
7. New technique identifies pathogens in patient samples faster, in great detail
8. Tidy knots are faster
9. New method to diagnose sepsis is faster, cheaper
10. Snow melts faster under trees than in open areas in mild climates
11. Carbon storage recovers faster than plant biodiversity in re-growing tropical forests
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Faster anthrax detection could speed bioterror response
(Date:4/5/2017)... -- Today HYPR Corp. , leading innovator in ... the HYPR platform is officially FIDO® Certified . ... that empowers biometric authentication across Fortune 500 enterprises and ... 15 million users across the financial services industry, however ... suites and physical access represent a growing portion of ...
(Date:4/3/2017)... April 3, 2017  Data captured by ... platform, detected a statistically significant association between ... to treatment and objective response of cancer ... to predict whether cancer patients will respond ... as well as to improve both pre-infusion potency ...
(Date:3/30/2017)... Trends, opportunities and forecast in this market ... (fingerprint, AFIS, iris recognition, facial recognition, hand geometry, vein ... use industry (government and law enforcement, commercial and retail, ... others), and by region ( North America ... Pacific , and the Rest of the World) ...
Breaking Biology News(10 mins):
(Date:10/7/2017)... Phoenix, Arizona (PRWEB) , ... ... ... than 15 years’ experience providing advanced instruments and applications consulting for microscopy ... the in-house expertise in application consulting, Nanoscience Analytical offers a broad range ...
(Date:10/7/2017)... , Oct. 6, 2017  The 2017 Nobel ... three scientists, Jacques Dubochet, Joachim Frank ... in cryo-electron microscopy (cryo-EM) have helped ... the structural biology community. The winners worked with ... now routinely produce highly resolved, three-dimensional images of ...
(Date:10/6/2017)... Washington, D.C. (PRWEB) , ... October 06, 2017 ... ... Cure) will host a lunch discussion and webinar on INSIGhT, the first-ever adaptive ... INSIGhT Principal Investigator, Dana-Farber Cancer Institute. The event is free and open to ...
(Date:10/5/2017)... ... 05, 2017 , ... Understanding the microbiome, the millions of bacteria that live ... You Are My Future, the newest exhibit on display at the University City Science ... condition through the lens of the gut microbiome. , Gut Love opens October ...
Breaking Biology Technology: