Navigation Links
Fast synthesis could boost drug development
Date:3/18/2014

researchers demonstrated that they could use this technology not only to synthesize peptides, but also combine these to form large synthetic proteins. To demonstrate the technology, they created an antibody mimic that has 130 amino acids, as well as a 113-amino-acid enzyme produced by bacteria. Chemistry graduate students Surin Mong and Alexander Vinogradov are lead authors of that paper, along with Simon.

The researchers have patented the technology, and MIT's Deshpande Center for Technological Innovation has given them a grant to help commercialize it. Pentelute says he believes that about 10 machines using the new technology would be enough to meet current demand, which is about 100,000 to 500,000 custom peptides per year.

Pentelute envisions that the technology could have an impact on synthetic biology comparable to rapid synthesis of short strands of DNA and RNA. These strands, known as oligonucleotides, take only a day or two to prepare and can be used to create custom genes to give cells new functions.

"That's what our aim is to have next-day or two-day delivery of these peptide units, to anyone in the world. That's really the dream," he says.


'/>"/>

Contact: Sarah McDonnell
s_mcd@mit.edu
617-253-8923
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. The genome of sesame sheds new lights on oil biosynthesis
2. New research indicates causal link between vitamin D, serotonin synthesis and autism
3. Substance in photosynthesis was at work in ancient, methane-producing microbes
4. Protein synthesis and chance
5. Quantum mechanics explains efficiency of photosynthesis
6. Targeted synthesis of natural products with light
7. Rensselaer researchers to map step-by-step mechanism of photosynthesis
8. In plant photosynthesis, scientists see clues for improving solar energy cells
9. Photosynthesis: Membranes in tight corners
10. UCI study reveals new mechanism for estrogen suppression of liver lipid synthesis
11. Science synthesis to help guide land management of nations forests
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/18/2015)... 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... growing mobile commerce market announces that its Wocket® smart wallet ... on the Mark", scheduled to air on WABC Radio (am770) ... th . The broadcast air- time for ... 8:00pm EST. NXT-ID, Inc.,s CEO Gino Pereira will ...
(Date:6/17/2015)... Germany , June 17, 2015 ... today launched new Investigator ® STR assay kits for ... the United States . The new genetic fingerprint kits ... markers (short tandem repeats or STRs) for DNA matching. They ... quality of DNA in each sample, a novel QIAGEN technology ...
(Date:6/17/2015)... BEACH GARDENS, Fla. , June 17, 2015 ... management solutions, today announced that its U.are.U ® ... Togo,s Eateries, Inc., a ... fast casual sandwich chain, to increase security, improve ... Crossmatch fingerprint readers enable instant, non-repudiable identity confirmation ...
Breaking Biology News(10 mins):NXT-ID, Inc.'s CEO Gino Pereira Talks About the Wocket Smart Wallet on WABC Radio, New York City, June 20th 2NXT-ID, Inc.'s CEO Gino Pereira Talks About the Wocket Smart Wallet on WABC Radio, New York City, June 20th 3QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 2QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 3QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 4QIAGEN Launches New Genetic Fingerprinting Kits for U.S. Forensic Labs 5Togo's Eateries Improve Security and Accountability with Crossmatch Fingerprint Readers 2Togo's Eateries Improve Security and Accountability with Crossmatch Fingerprint Readers 3
... that humanity reacts to climate change may do more damage ... unless we plan properly, an important new study published in ... a group of other leading scientists has concluded. The ... at efforts to both reduce emissions of greenhouse gases and ...
... the impacts of invasive species, pollution and environmental ... discuss widespread environmental changesfrom the recent discovery of ... implications of mercury found in bottlenose dolphin skin, ... disasters in the U.S.at the Ecological Society of ...
... response crews now have new information available when making decisions ... sea or where to find mariners in distress. NOAA partners ... data buoy off Escambrn beach to provide data on winds, ... Juan and the island,s Atlantic coast. The new buoy ...
Cached Biology News:The worst impact of climate change may be how humanity reacts to it 2The worst impact of climate change may be how humanity reacts to it 3Scientists find new evidence of genetically modified plants in the wild 2Scientists find new evidence of genetically modified plants in the wild 3Scientists find new evidence of genetically modified plants in the wild 4
(Date:7/3/2015)... , July 3, 2015 ... till 22 september 2015 på  http://www.openinnovationinscience.at ... Innovation in Science" som hålls i ... en färsk undersökning med internationella forskare och ... (LBG) är hälsovetenskapens två största utmaningar bristen ...
(Date:7/2/2015)... ... 03, 2015 , ... Cuvettes have been used in countless labs for decades. In the ... they needed. As expected, this was a daunting and tiring process looking at endless ... were not able to navigate the complex catalog structure. , Now thanks to FireflySci, scientists ...
(Date:7/2/2015)... Calif. (PRWEB) , ... July 02, 2015 , ... Sleepless ... improve an individual’s quality of sleep, launched its Indiegogo campaign on June 23. Sound ... Luzi's voice command technology makes it effortless to use, while the integration of the ...
(Date:7/1/2015)... 2015   Decision Resources Group finds ... Otezla are its oral administration, alternative mechanism of ... surveyed rheumatologists. Otezla was the first oral therapy ... active psoriatic arthritis in the United ... includes conventional oral treatments including disease-modifying antirheumatic drugs ...
Breaking Biology Technology:Lansering av världens första program för öppen innovation för att utbilda forskare 2Lansering av världens första program för öppen innovation för att utbilda forskare 3New Cuvette E-Commerce Website Launched by FireflySci 2Luzi Smart Lamp Recently Launched Indiegogo Campaign 2Luzi Smart Lamp Recently Launched Indiegogo Campaign 3Surveyed Rheumatologists Report That Otezla's Oral Administration is its Single Greatest Advantage Over Currently Available Treatment Options 2Surveyed Rheumatologists Report That Otezla's Oral Administration is its Single Greatest Advantage Over Currently Available Treatment Options 3
... Researchers at the Harvard School of Engineering and Applied ... Institute (WPI), have demonstrated, for the first time, that ... affected by the surrounding dielectric and can be modified ... The finding, published in the April 6 issue of ...
... Cadence Pharmaceuticals, Inc. (Nasdaq: CADX ), a biopharmaceutical ... principally for use in the hospital setting, announced today that ... corporate overview at the following investment conferences: , ... of America Merrill Lynch 2009 Healthcare Conference at the Palace ...
... Calif., May 5 Ambry ... (CGH) using oligonucleotide arrays through a partnership with ... are associated with over 270 genetic syndromes can be ... and mitochondrial array. The partnership with Baylor College ...
Cached Biology Technology:Scientists demonstrate effect of confining dielectrics on semiconductor nanowire conductivity 2Cadence Pharmaceuticals' CEO Ted Schroeder to Present at Two Investment Conferences During the Month of May 2009 2Ambry Genetics Announces the Addition of Array CGH Services Through Partnership With Baylor College of Medicine 2
X-Gal (5-Bromo-4-Chloro-3-Indoyl-beta -D-Galactopyranoside)...
APG5 autophagy 5-like (S. cerevisiae)...
Human Jagged 2 Biotinylated Affinity Purified PAb...
Mouse/Rat WNK1 Affinity Purified Polyclonal Ab...
Biology Products: