Navigation Links
Fast prediction of axon behavior
Date:7/20/2011

Researchers at Case Western Reserve University have developed a computer modeling method to accurately predict how a peripheral nerve axon responds to electrical stimuli, slashing the complex work from an inhibitory weeks-long process to just a few seconds.

The method, which enables efficient evaluation of a nerve's response to millions of electrode designs, is an integral step toward building more accurate and capable electrodes to stimulate nerves and thereby enable people with paralysis or amputated limbs better control of movement.

To increase the accuracy of the results, the researchers included a key parameter overlooked in past mathematical approaches that were equally fast, but inaccurate. With the new techniques, electrode design can be optimized using advanced algorithms based on natural genetics.

An explanation of the work, which the team hopes others in the field will freely use, and a second method that was simpler and faster but proved less effective, are now available online in the Journal of Neural Engineering.

"We believe this will allow the next generation of computer-aided development of electrodes," said Dustin Tyler, associate professor of biomedical engineering at Case School of Engineering and senior author of the paper.

Since his graduate school days, Tyler has been developing electrodes to stimulate nerves in paralyzed patients and amputees. Taking the large step from animal models to human clinical trials can be improved with better computer modeling, he said.

"Finding the optimal way to stimulate a nerve is kind of like the 'travelling salesman' trying to figure out which is the most efficient route through a group of cities," Tyler said.

Mapping each possible route and figuring the time spent on the road is very difficult to do with a simple equation.

But, using a complex mathematical formula called a genetic algorithm to simultaneously consider all th
'/>"/>

Contact: Kevin Mayhood
kevin.mayhood@case.edu
216-368-4442
Case Western Reserve University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Researchers develop new self-training gene prediction program for fungi
2. British scientists go cloud-hopping in the Pacific to improve climate predictions
3. Climate change expert to discuss grim global warming predictions
4. NASA-enhanced dust storm predictions to aid health community
5. Decisive action needed as warming predictions worsen, says expert
6. Phasic firing of dopamine neurons is key to brains prediction of rewards
7. Counting sheep in climate change predictions
8. New lab test offers better prediction of HIV microbicide safety
9. UTSA wins $5 million for new Simulation, Visualization and Real-Time Prediction Center
10. NOAA awards funds to improve toxic algal bloom predictions in the Western Gulf of Mexico
11. Co-conspirator cells could hold key to melanoma prediction, prevention
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/1/2015)... --  Medisafe ™, the leading global medication management platform ... and Android smartphones and tablets, announces today ... to allow patients to track and correlate their adherence ... will be able to visualize in real-time how taking ... as glucose levels and blood pressure. "Patients ...
(Date:3/30/2015)... , Mar. 26, 2015 Research and Markets ... of the "Global Gesture Recognition Market in Automotive ... The analysts forecast the Global Gesture Recognition market in ... over the period 2013-2018. Gesture recognition is ... to different gestures of an individual. Gesture recognition technology ...
(Date:3/24/2015)... DUBLIN , Mar. 24, 2015 Research and Markets ... "Face and Voice Biometrics - Global Strategic Business Report" report ... for Face and Voice Biometrics in US$ Thousands by the following ... analytics for the US, Canada , ... , Middle East & ...
Breaking Biology News(10 mins):Medisafe Announces Launch of Biometric Integration, Enabling Patients to Stay Adherent to Their Meds and See Tangible Health Results 2Global Gesture Recognition Market in Automotive Sector Report 2015 - Growing Number of Partnerships 2Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 2Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 3Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 4Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 5Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 6
... significant problem around the world. In the United States, ... of the annual calls to the nation's Poison Control ... guide to the harmful potential of plants, Handbook of ... to the toxic plants encountered everywhere, both inside and ...
... pose a threat to future sea levels using satellite ... Science. , Experts from the University of Edinburgh and ... Greenland were having on global sea level in a ... that together these two ice-sheets were responsible for a ...
... those that are hydrophobic or water-repellant, to tumors or ... innovative delivery systems that keep these drugs intact until ... at Buffalo’s Institute for Lasers, Photonics and Biophotonics and ... in which the delivery system is the drug itself. ...
Cached Biology News:Illuminating the dark side of plants 2No carrier necessary: This drug delivers itself 2
(Date:4/20/2015)... NC and Champaign, IL (PRWEB) April 20, 2015 ... today the establishment of its 12th clinical research site: ... PMG Research has assumed operation of the clinical research ... expanding PMG’s footprint outside the Southeast to a second ... within a 150 multi-specialty physician practice enhances PMG’s access ...
(Date:4/20/2015)... ANGELES , April 20, 2015  "Everybody is ... we do to patients is frankly brutal. We,ve got ... in a cancer ward, or witnessed a loved one ... you,ve witnessed firsthand the devastation chemotherapy and other treatments ... most people want to give up and succumb to ...
(Date:4/20/2015)... MIAMI (PRWEB) April 20, 2015 ... attend The Aesthetic Meeting 2015, an annual gathering of ... Alfredo Hoyos, M.D., is scheduled to introduce the company’s ... injection techniques with adipose-derived stem cell techniques. , ... that concern patients in the aesthetic field, including facial ...
(Date:4/17/2015)... CA (PRWEB) April 17, 2015 CIO ... ) for its 20 Most Promising Pharma and Life ... on MMIS’s MediSpend global compliance software platform for life ... is selected by a panel of experts and members ... technology entrepreneurship. “MMIS’s MediSpend Platform has been on our ...
Breaking Biology Technology:PMG Research Announces the Formation of its 12th Site in Champaign-Urbana, IL 2PMG Research Announces the Formation of its 12th Site in Champaign-Urbana, IL 3Is Dr. Craig Dionne the Steve Jobs of Cancer Research? 2Global Stem Cells Group to Host Featured Speaker at The Aesthetic Meeting 2015 in Montreal 2Global Stem Cells Group to Host Featured Speaker at The Aesthetic Meeting 2015 in Montreal 3MMIS Chosen by CIO Review as Top 20 Most Promising Pharma and Life Science Technology Solution Providers 2015 2
... a.m. Eastern Time HOST: Dr. Candace ... Kendle, Chairman and CEO, CINCINNATI, Oct. ... and simultaneous webcast Oct. 31,at 8:30 a.m. Eastern Time to discuss its ... follow. (Logo: http://www.newscom.com/cgi-bin/prnh/20030429/KNDLLOGO ) Webcast Instructions To ...
... RALEIGH, N.C., Oct. 10 Campbell Alliance, the leading,management ... announced that the firm was recognized as one of ... area of North Carolina by the,Triangle Business Journal, ranking ... firm at the Triangle Business Journal,s annual Best,Places to ...
... National Surgical Hospitals (NSH), a,leading owner and operator ... has acquired a majority stake in Sterling Ridge ... in,The Woodlands, Texas. NSH acquired its share ... nine physicians. It intends to convert the facility,into ...
Cached Biology Technology:Kendle Invites You to Attend Its Third Quarter 2007 Earnings Conference Call and Webcast 2Campbell Alliance Named 'Best Place to Work' by Triangle Business Journal 2National Surgical Hospitals Acquires Majority Share of Houston-Area Surgery Center 2
Anti-gamma Glutamyl Transferase (gammaGT) Host: mouse monoclonal Species Reactivity: human Applications: WB, IP, FC Storage: 4C...
... polyclonal to Cholesterol Oxidase Immunogen ... Cross-reacts with bacteria. Not yet tested ... Cholesterol oxidases exist as both type I ... in bacterial pathogenesis. In addition, they are ...
Goat polyclonal to XAGE1 ( Abpromise for all tested applications). Antigen: Synthetic peptide: CGFGFRRQGEDNT, corresponding to C terminal amino acids 149-160 of Human XAGE1 Entrez Gene ID: 9...
MDMA Mouse Monoclonal Antibody (Clone 3G8)...
Biology Products: