Navigation Links
Fast AFM probes measure multiple properties of biomolecules or materials simultaneously
Date:4/16/2008

material and how stiff and sticky it is.

An output signal is generated only when there is an interaction force on the probe. In other words, transient interaction forces can be measured during each tap of the tip with high resolution and without any background signal.

In the February 27 issue of the journal Nanotechnology, the researchers described using the FIRAT probe to characterize the elasticity, surface energy and adhesion hysteresis of three polymers and a silicon sample. The quantitative results were mapped in addition to topography.

FIRAT probes made of dielectric materials with embedded actuation electrodes have also been designed for operation in liquids. The design of these membrane-based probes also makes them relatively easy to arrange in arrays in which each probe can move independently. One application of such an array is fast parallel measurements of forces between biological molecules.

In collaboration with Cheng Zhu, Regents Professor in the Wallace H. Coulter Department of Biomedical Engineering, Degertekin is using the probe to measure the force between two interacting biological molecules and unbinding forces between two molecules.

By testing different molecules and buffer solutions, researchers can determine the probability of molecule adhesion, a process that requires many repetitive measurements. This has implications in drug discovery, where determining how frequently certain soft biological molecules adhere to each other is important.

Rather than moving a single cantilever up and down a thousand times, we have developed a membrane that would allow parallel measurements of molecules to get thousands of measurements at one time, said Degertekin.

This new technique was described in the February 2007 issue of the journal Nanotechnology. For different applications, Degertekin can adjust the stiffness of the membranes.

The best mechanical measurements of surfaces or
'/>"/>

Contact: Abby Vogel
avogel@gatech.edu
404-385-3364
Georgia Institute of Technology Research News
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Comet probes reveal evidence of origin of life, scientists claim
2. Studying component parts of living cells with carbon nanotube cellular probes
3. New MIT tool probes brain circuits
4. Astronomy technology brings nanoparticle probes into sharper focus
5. Team probes mysteries of oceanic bacteria
6. ESF conference probes waters mysterious interactions at molecular level
7. Bioengineers at University of Pennsylvania devise nanoscale system to measure cellular forces
8. UCR engineers to develop new tool to measure how environmental exposures affect health
9. New microsensor measures volatile organic compounds in water and air on-site
10. Unprecedented global measurement network achieves full coverage of oceans
11. Measurement Specialties, Inc. Announces Impact of German Business Tax Reform 2008 Resulting in Lower Combined German Tax Rate - Impacts 2Q08 Reported Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Fast AFM probes measure multiple properties of biomolecules or materials simultaneously
(Date:12/19/2014)... Research and Markets ( http://www.researchandmarkets.com/research/8kmfcn/iphone_5s ... "iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 & ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... July 2012, Apple introduced the fingerprint reading feature ... only device of Apple incorporating such a feature, ...
(Date:12/19/2014)... , Dec. 18, 2014 Research and Markets ... of the "Micro Market Monitor: North America Perimeter ... http://photos.prnewswire.com/prnh/20130307/600769 The ... at a CAGR of 3.6% from 2014 to 2019. ... this market, Canada is expected ...
(Date:12/19/2014)...  23andMe, Inc., the leading personal genetics company, today ... differences in genetic ancestry of individuals from across ... immigrants first arrived more than four hundred years ago, ... as a meeting place for peoples from different continents. ... mixing of peoples with African, European, and American origins ...
Breaking Biology News(10 mins):iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 & Sapphire - Technology Report 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 323andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4
... , This release is available in ... discovered a mechanism that helps to explain resilience ... work. The new findings, in the reward circuit ... high tech dragnet for compounds that boost the ...
... Researcher in the University of Bristol,s School of Biological Sciences ... as a cue to find coral reefs, but was amazed ... larvae which must quickly find a safe place to ... can do the same thing. The team designed a ...
... For years, researchers have known that resistance exercise training ... another force can be one of the most effective ... But many older people are unable to get the full ... as arthritis that prevent them from lifting enough weight to ...
Cached Biology News:Resilience factor low in depression, protects mice from stress 2Resilience factor low in depression, protects mice from stress 3Muscle mass in elderly boosted by combining resistance exercise and blood flow restriction 2
(Date:12/19/2014)... 19, 2014 Research and Markets ... the "Technology Innovations in Smart Fabrics (Technical ... http://photos.prnewswire.com/prnh/20130307/600769 The ... offers a detailed assessment on technological advancements and ... 1. The Smart Fabrics market ...
(Date:12/19/2014)... (PRWEB) December 18, 2014 Ed Bilsky, ... of the Center for Excellence in the Neurosciences (CEN), ... England, has been selected as a member of the ... the first neuroscientist from Maine to receive this honor. ... organization supported entirely by the Dana Foundation. Its ...
(Date:12/19/2014)... The empty capsules market is ... population and technological innovations in the empty capsules ... catalysing the growth of the empty capsules market. ... , Scope of Report , The report will ... entrants/smaller firms to gauge the pulse of the ...
(Date:12/19/2014)... 18, 2014   ISN has released its ... Indicators publication series. With data aggregated from ... in 2013 within its online contractor management platform, ISNetworld, ... performance indicator (KPI) statistics. The ... publication is available in two industry specific volumes: ...
Breaking Biology Technology:Technology Innovations in Smart Fabrics (Technical Insights) 2UNE's Ed Bilsky Named Member of Dana Alliance for Brain Initiatives 2UNE's Ed Bilsky Named Member of Dana Alliance for Brain Initiatives 3Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 2Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 3Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 4ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 2ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 3
... politics aside, every biologist knows that men and women truly ... area where those differences come to the fore: around 80 ... Social play behaviors also differ greatly between the sexes - ... girls. , ,Early in human development, critical brain proteins known ...
... The life sciences company Promega announced on Tuesday a ... that had been pending before the U.S. District Court ... Promega will hold a worldwide non-exclusive license from Benitec ... DNA-directed RNA interference (ddRNAi) technology. Promega will also receive ...
... an online provider of digital sheet music, announced on Tuesday ... Group to provide Word Music's collection of Christian music on ... , ,Word Music, a division of Warner Music Group based ... music from Christian songwriters such as Amy Grant, Point Of ...
Cached Biology Technology:Gender hormones may lend to social disorder therapies 2