Navigation Links
Family history of liver cancer increases risk of developing the disease
Date:4/24/2012

A family history of liver cancer is reported to increase risk of developing hepatocellular carcinomas (HCC), independent of hepatitis according to findings published in the May issue of Hepatology, a journal of the American Association for the Study of Liver Diseases. The study also shows 70-fold elevated risk of HCC in those with liver cancer in the family and markers for hepatitis B (HBV) or hepatitis C (HCV).

Liver cancer ranks sixth in incidence and the third cause of mortality worldwide. According to the World Health Organization (WHO) liver cancer was responsible for 700,000 deaths in 2008, with HBV and HCV accounting for 78% of all cases of HCC. A vaccine for HBV has been available since 1982; however prior studies have shown familial clustering of HCC in East Asia where HBV is common. While medical evidence reports family history to be related to HCC risk, little is known of this relationship in non-Asian populations.

"There is a high incidence of liver cancer in southern Italy which is likely a result of a higher frequency of HCV in this area," explains Professor Carlo La Vecchia from the Istituto di Ricerche Farmacologiche ''Mario Negri" and the University of Milan in Italy. "Our study investigated the relationship between family history and liver cancer in a Western population."

The case-control study was carried out between January 1999 and July 2002, and included 229 cases of HCC and 431 hospital controls. HCC patients ranged in age from 43 to 84 years, providing survey information and blood samples. The control group included patients admitted to hospital for conditions not related to tumors. Analysis of data on family history and liver cancer updated to April 2011 was also performed.

Results show that 75% of the cases and 11% of controls showed evidence of HBV and HCV infection. Family history of liver cancer was associated to HCC risk after adjusting for chronic HBV and HCV. Compared to subjects wit
'/>"/>

Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Page: 1 2

Related biology news :

1. Merkin Family Foundation to fund next generation of Broad Institute scientists
2. New miniature grasshopper-like insect is first member of its family from Belize
3. Close family ties keep microbial cheaters in check, study finds
4. Do plants perform best with family or strangers? Researchers consider social interactions
5. Scientists determine family tree for most-endangered bird family in the world
6. Long bone shape: A family affair
7. Researchers at Cruces Hospital describe new syndrome of slight family intellectual disability
8. The risk of suffering from insomnia is 67 percent higher if a family member is insomniac
9. Highlights of upcoming conference on aldosterone & the ENaC/Degenerin family of ion channels
10. BUSM professor authors book on how knowledge about genes and family history can save lives
11. Methyl magnet genes can cause family cancer risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/20/2014)... BOSTON Although doctors have long known that people with ... lymphoblastic leukemia (ALL) during childhood, they haven,t been able ... Cancer Institute investigators has uncovered a connection between the ... by the journal Nature Genetics , the researchers ... chromosomal abnormality in Down syndrome to the cellular havoc ...
(Date:4/18/2014)... of emergency contraceptive pills in Peru found that ... of substandard quality or falsified. Many pills released ... wrong active ingredient. One batch had no active ... fake drugs, researchers at the Georgia Institute of ... to quickly assess suspected counterfeit drugs and then ...
(Date:4/18/2014)... population predicted to reach 9 billion by 2050 ... considers human-altered landscapes such as farmland, according to ... that supports it might be an increasingly scarce ... of the land surface is directly affected by ... impacts such as climate change. But what if ...
Breaking Biology News(10 mins):Dana-Farber researchers uncover link between Down syndrome and leukemia 2Dana-Farber researchers uncover link between Down syndrome and leukemia 3Counterfeit contraceptives found in South America 2Counterfeit contraceptives found in South America 3Stanford researchers rethink 'natural' habitat for wildlife 2Stanford researchers rethink 'natural' habitat for wildlife 3Stanford researchers rethink 'natural' habitat for wildlife 4
... Premio Nacional de Investigacin in Madrid at the end of ... At the award ceremony attended by the Spanish royal family ... King Juan Carlos himself. The jury of the Spanish science ... on the marine ecosystem. The work he has conducted over ...
... and burrows discovered in Victoria, Australia, have provided the ... as far back as the Mesozoic Era, says Emory ... on the finds. "Studying the fossil burrows gives ... about 115 million years ago, when the continent was ...
... MIT team has used an engineering approach to show that ... by measuring what goes into and out of the system. ... to look at the inner workings of a complicated biological ... study systems in their natural state. The MIT researchers ...
Cached Biology News:Springer author Carlos M. Duarte awarded Spanish science prize 2Oldest Australian crayfish fossils provide missing evolutionary link 2MIT applies engineering approach to studying biological pathways 2
(Date:1/15/2014)... , Jan. 15, 2014 TaiGen Biotechnology Company, Limited ... agreement with R-Pharm, a leading Russian pharmaceutical company, to ... Russian Federation , Turkey ... States (CIS). Nemonoxacin is a novel antibiotic for the treatment ...
(Date:1/14/2014)... Carahsoft and CDS Federal Services have scheduled ... 2pm EST (11am PST), “Natural Language Processing: Converting Raw ... technology can turn raw, heterogeneous data into actionable knowledge ... online webinar will last approximately one hour. , Synopsis: ...
(Date:1/14/2014)... Jan. 14, 2014  3D Communications, a leading provider of strategic communications ... and media events in the United States ... Virginia Cox , JD, is returning to the firm,s ... re-joins 3D after more than two years of service as ...
(Date:1/14/2014)... NY (PRWEB) January 14, 2014 EquitiesIQ, ... Alliqua, Inc. (OTCQB: ALQA). Alliqua is an emerging biomedical ... serve the wound care market. , Free report download: ... restructured with a seasoned management team and Board, which ...
Breaking Biology Technology:TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2Former FDA Associate Commissioner Returns To 3D Communications 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3
... Halozyme Therapeutics,Inc. (Nasdaq: HALO ), a biopharmaceutical ... that it will present at two investor conferences in ... Summit to be held at the,Mark Hopkins InterContinental Hotel ... a.m. Pacific Time (12:30 p.m. Eastern Time); and, ...
... Masimo (Nasdaq:,MASI), the inventor of Pulse CO-Oximetry ... purchasing the Masimo Radical-7, the company,s flagship,product, ... as a standard feature., Conventional pulse ... drops in oxygen saturation values, known as ...
... Washington, DC Widespread use of nanoscale silver ... benefits against the possibility of significant environmental risk, ... this emerging technology, according to a new report ... (PEN). , But existing information about the ...
Cached Biology Technology:Halozyme Therapeutics to Present at Upcoming Investor Conferences 2Masimo Announces Desaturation Index 3D Alarm as Standard Feature in All Radical-7 Pulse CO-Oximetry Devices 2Masimo Announces Desaturation Index 3D Alarm as Standard Feature in All Radical-7 Pulse CO-Oximetry Devices 3Nanoscale silver: No silver lining? 2Nanoscale silver: No silver lining? 3
...
... trays and universal trays make vessel ... Shaking speed: 40 - ... amplitude Clamps for Erlenmeyer ... including Fernbach flasks Hinged ...
... kit allows for rapid, convenient, and efficient ... bind/wash/elute process utilizes a spin column to ... for concentration of proteins which were electro-eluted ... strong ion exchangers, offering high binding capacity ...
In Western blotting antibodies recognize 94 K protein band, which corresponds to S-layer protein...
Biology Products: