Navigation Links
FSU researcher's discovery leads to $1.5 million grant, potential new treatment of liver fibrosis
Date:10/17/2008

e normal wound healing resulting from the body's efforts to repair injured tissue.

"We had evidence of its existence, but we didn't have the protein," Stefanovic said. "We had been looking for this particular protein for several years until we used some very sophisticated methods of cloning. When I saw the results of the binding of the protein to our target I knew immediately we had found the right one.''

Stefanovic said he doesn't believe there will ever be a cure for liver fibrosis but that research and development will one day lead physicians to be able to slow down the progress of the disease.

"At least if we slow down the chronic process, instead of dying in five years the patient will live 15 years or more,'' he said.

"The goal is to suppress excessive collagen synthesis. In order to do that we have to know the molecular mechanisms that regulate manufacture of the protein and then see what has gone wrong when the liver is creating excess collagen.

"Then we will be able to find specific points in this process where we can intervene, by designing either a drug of some kind or a therapeutic agent that will allow us to block these key points and slow down the scarring. Cloning of this protein is a major step toward this goal."


'/>"/>

Contact: Doug Carlson
doug.carlson@med.fsu.edu
850-645-1255
Florida State University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Researchers identify promising gene target for neuroblastoma therapy
2. Researchers continue to find genes for type 1 diabetes
3. Researchers uncover worlds oldest fossil impression of a flying insect
4. Researchers discover baldness gene: 1 in 7 men at risk
5. Researchers design artificial cells that could power medical implants
6. Circadian clock may be critical for remembering what you learn, Stanford researchers say
7. Burnham researchers turn cancer friend into cancer foe
8. Researchers document worlds mammals in crisis
9. Oklahoma researchers support biodiversity in biofuels production
10. UCR researchers propose minocycline as a promising drug for patients with Fragile X syndrome
11. Childrens National researchers develop novel anti-tumor vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2015)... ATL Technology, LLC, a top provider of electromechanical contract manufacturing ... headquartered in Springville, Utah , has announced ... corporation with locations in Santa Clara, CA ... ). This acquisition will incorporate MedConx,s manufacturing facility ... existing facility in Costa Rica , resulting ...
(Date:6/25/2015)...  TAKE Solutions Ltd., a global business technology solutions ... Patent and Trademark Office (USPTO) for its "Method for ... Clinical Accelerators to reduce the time taken to standardize ... without the accelerators), thus reducing time to market. ... the heart of the patented Clinical Data Standardization Process ...
(Date:6/24/2015)... JOSE, Calif. , June 24, 2015 /PRNewswire/ ... developer of human interface solutions, today announced that ... sensor to provide secure authentication for its latest ... recently reached more than 200 million shipments of ... with Sharp reinforces Synaptics, strength, scalability and leadership ...
Breaking Biology News(10 mins):ATL Technology Announces Acquisition of MedConx, Inc. and Expanded Global Footprint 2TAKE Solutions Awarded Patent By USPTO 2Synaptics Brings Natural ID Technology to Sharp's Newest Flagship Smartphone 2
... the Southern Ocean, large quantities of surface-drifting plankton algae are ... surface waters, which can affect the global carbon dioxide cycle. ... which has just drawn to a close in Cape Town ... Wegener Institute, part of the Helmholtz Association. On February 5, ...
... Rochet, a research scientist at IFREMER (The French Research ... the prestigious Pew Fellowship in Marine Conservation to determine ... to the delicately balanced marine ecosystem. She will use ... use of that technique, and to further improve its ...
... YORK CITY - Dr. Ussif Rashid Sumaila, an Associate ... in Vancouver, Canada, is among five ocean experts to ... Conservation, which supports critical marine conservation projects around the ... the financial factors contributing to unsustainable commercial fishing and ...
Cached Biology News:Antarctic expedition provides new insights into the role of the Southern Ocean for global climate 2Antarctic expedition provides new insights into the role of the Southern Ocean for global climate 3Antarctic expedition provides new insights into the role of the Southern Ocean for global climate 42008 Pew Fellowship in Marine Conservation awarded to Dr. Marie-Joëlle Rochet from IFREMER 22008 Pew Fellowship in Marine Conservation awarded to Dr. Marie-Joëlle Rochet from IFREMER 32008 Pew Fellowship in Marine Conservation awarded to Dr. Marie-Joëlle Rochet from IFREMER 42008 Pew Fellowship in Marine Conservation awarded to Dr. Ussif Rashid Sumaila 22008 Pew Fellowship in Marine Conservation awarded to Dr. Ussif Rashid Sumaila 32008 Pew Fellowship in Marine Conservation awarded to Dr. Ussif Rashid Sumaila 4
(Date:6/26/2015)... 2015  SeraCare Life Sciences, a leading partner ... that it has signed a Cooperative Research and ... (NCI), part of the National Institutes of Health, ... cancer assays.  The CRADA will investigate the development ... DNA biosynthetics spiked into a genomic DNA background ...
(Date:6/26/2015)... VANCOUVER , June 26, 2015 /PRNewswire/ - iCo ... ICOTF), today announced that all nominees listed in ... as directors at its 2015 Annual Meeting of ... a vote by ballot, the following 5 nominees ... iCo Therapeutics to serve until the Company,s next ...
(Date:6/26/2015)... 2015  A San Francisco company, Pembient, recently announced ... rhino horn: beer in China ... In response to the emerging industry, two leading rhino ... of synthetic rhino horn.  The ... Rhino International (SRI) released a joint statement ...
(Date:6/26/2015)... , ... June 26, 2015 , ... ... announced that its SimplePrep™ technologies have been integrated into a sample prep module ... Station (ISS) as a part of the NASA’s WetLab-2 Project. , On June ...
Breaking Biology Technology:SeraCare Life Sciences Signs CRADA with NCI to Advance Cancer Diagnostics 2SeraCare Life Sciences Signs CRADA with NCI to Advance Cancer Diagnostics 3iCo Therapeutics Announces Voting & Election Results from Annual Meeting of Shareholders 2iCo Therapeutics Announces Voting & Election Results from Annual Meeting of Shareholders 3Rhino Experts Oppose Synthetic Rhino Horn as Solution to Poaching Crisis 2Claremont BioSolutions’ SimplePrep™ Products Deployed in NASA Wetlab-2 Project Slated for June 28th Flight to International Space Station aboard SpaceX CRS-7 2Claremont BioSolutions’ SimplePrep™ Products Deployed in NASA Wetlab-2 Project Slated for June 28th Flight to International Space Station aboard SpaceX CRS-7 3
... , , Multiporator / Electroporator 2510 , , , , , , ... Transformation Protocol , Protocol No. 4308 915.506 12/2001 , , ... , , , Microorganism , ... Cell type , Bacteria, gram negative, ...
... Multiporator / Electroporator 2510 , , , , , , , ... Protocol No. 4308 915.538 04/2002 , , , ... , Microorganism , ... Cell type , Bacteria, gram positive, , ...
... , Multiporator / Electroporator 2510 , , , , , , ... Protocol , Protocol No. 4308 915.502 12/2001 , , ... , , Microorganism , ... Cell type , Bacteria, gram negative, , ...
Cached Biology Technology:Borrelia burgdorferi 2Bifidobacterium animalis 2Agrobacterium tumefaciens 2
...
TRIzol Reagents are ready-to-use monophasic solutions of phenol and guanidine isothiocyanate suitable for isolating total RNA DNA and proteins (16)....
...
...
Biology Products: