Navigation Links
FDA grants cardiotrophin-1 Orphan Drug status for acute liver failure treatment to Digna Biotech
Date:9/21/2011

Digna Biotech, a Spanish biotechnological company, announces that the Food and Drug Administration (FDA) granted cardiotrophin-1 (CT-1) Orphan Drug status for use in the treatment of acute liver failure (Designation request 11-3507).

This provides more incentives to work on cures for this disease, which has an incidence of 2,000 cases per year in the United States, according to the findings reported by Acute Liver Failure Study Group (ALFSG) (Lee, Squires et al. 2008). In August, the European Medicine Agency (EMA) granted also the Orphan Drug status of cardiotrophin-1 for the treatment of acute liver failure (EU/3/11/893).

Pablo Ortiz, CEO at Digna Biotech, commented, "The experimental findings that support this new indication of CT-1 are very strong and we are confident that they can be converted in a clinical valuable effect in patients suffering from acute liver failure of different etiology. Acute liver failure is a very severe condition with a high mortality rate and very limited therapeutics possibilities that needs effective treatments. The advantage of having the product at the clinical stage starting Phase I allow us to plan Phase II for this indication by the end of next year."

Acute liver failure is a rare disease that is manifested by a sudden loss of the normal liver functions in a patient with a previously normal liver and without evidence of chronic liver disease. The most common first sign of liver failure is yellowing of the skin (jaundice). This condition has serious complications such as bruising and bleeding due to impaired blood clotting as well as cerebral edema (swelling around the brain), convulsions (fits) and coma. The most common causes of acute liver failure are toxic damage (e.g. alcohol and drugs such as paracetamol) or viral hepatitis (an infectious disease that affects the liver). Acute liver failure is a long-term debilitating and life-threatening disease because of its damaging effects on the brain a
'/>"/>

Contact: Nuria Safont
nsafont@dignabiotech.com
Digna Biotech S.L
Source:Eurekalert

Page: 1 2

Related biology news :

1. EPA grants help Wayne State researchers stave off Great Lakes environmental invaders
2. CWRU School of Dental Medicine receives $2.6 million in grants
3. Lincoln Park Zoo awarded 2 significant grants for science education
4. Grants awarded to help bring promising bioscience discoveries to market
5. American Health Assistance Foundation announces latest grants for innovative vision research
6. S.L.E. Lupus Foundation announces new grants to further NYC scientists leadership in lupus research
7. Altitude Research Center wins major Pentagon grants
8. Pancreatic Cancer Action Network-AACR Pathway to Leadership Grants awarded to early-career investigators
9. Scientists awarded carcinoid tumor and pancreatic neuroendocrine tumor research grants
10. $38.4M NHMRC program grants extend cancer and blood cell research
11. NIFA announces grants to study the effects of climate change on agricultural and forest production
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/11/2015)... , February 11, 2015 ... research report "Access Control Market by Product (Cards and ... Residential, Military and Defense, Government, Industrial, Healthcare, Education) and ... published by MarketsandMarkets, the Access Control Market ... 2020, growing at a CAGR of 10.6% ...
(Date:2/5/2015)... , 5. Februar 2015 ... spezialisiertes Logistikunternehmen und hat eine neue Marketingkampagne ... Logistikfirma (Clinical Logistics Organization – CLO) der ... Kampagne lautet First , mit Schwerpunkt ... Foto: http://photos.prnewswire.com/prnh/20150205/173753 Logo ...
(Date:2/5/2015)... Conn. , Jan. 26, 2015 NXT-ID, Inc. ... the "Company"), a biometric authentication company focused on the ... new corporate website ( http://www.nxt-id.com/ ) as part of ... smart wallet. The Company launched its new consumer website ... Gino Pereira , CEO of NXT-ID said, "Our new ...
Breaking Biology News(10 mins):Access Control Market Worth $10.4 Billion by 2020 2Access Control Market Worth $10.4 Billion by 2020 3Access Control Market Worth $10.4 Billion by 2020 4Marken startet Kampagne mit Patienten im Mittelpunkt 2Marken startet Kampagne mit Patienten im Mittelpunkt 3NXT-ID, Inc. Launches New Corporate Website As Part Of Ongoing 2015 Branding Initiatives For Wocket Smart Wallet 2NXT-ID, Inc. Launches New Corporate Website As Part Of Ongoing 2015 Branding Initiatives For Wocket Smart Wallet 3
... who has watched crime dramas on TV knows that ... from evidence gathered at a crime scene, establish a ... has been wrongly jailed. A lesser known but rapidly ... paternal ancestrya process known as genetic genealogy. The laboratories ...
... symptoms until it has spread to other organs, when it ... great promise for extending survival during later disease stages, but ... of the first discoveries of its kind, UC Davis Cancer ... own repair mechanism and, in so doing, help make chemotherapy ...
... Texas Health Science Center at Houston (UTHSC-Houston) were honored ... at the 2008 American Heart Association,s Scientific Sessions in ... killer. UT faculty members recognized were: Nobel Laureate ... Foundation Institute of Molecular Medicine for the Prevention of ...
Cached Biology News:NIST guides genetic genealogy labs toward improved accuracy 2UC Davis discovery offers hope for treating kidney cancer 2UT faculty members win American Heart Association awards for advancing research 2UT faculty members win American Heart Association awards for advancing research 3
(Date:2/27/2015)... Halifax, Nova Scotia (PRWEB) February 27, 2015 ... clinical stage vaccine and immunotherapy company, today announced ... approved its application for Fast Track designation and ... DPX-Ebola vaccines, in conjunction with the mutual co-development ... had previously obtained Fast Track designation for the ...
(Date:2/27/2015)... 27, 2015 Cytokinetics, Incorporated (Nasdaq: CYTK) ... 28 with patients and health care advocates in the ... Disease Day®. Rare Disease Day is dedicated to ... to the special challenges faced by patients with rare ... is proud to stand alongside patients and caregivers representing ...
(Date:2/26/2015)...  23andMe, the leading personal genetics company, today announced ... Officer and Corporate Counsel. Black brings a strong background ... as health care regulations. As a member of the ... reviewing, updating and enhancing the company,s privacy and consent ... joined the company January 5, 2015 and reports to ...
(Date:2/26/2015)... , Feb. 26, 2015 DuPont Executive ... priorities driven by key research advancements and product launches ... today,s Bank of America Merrill Lynch 2015 Global Agriculture ... challenge of building grain supplies the last two years, ... at the pace of the last decade, when demand ...
Breaking Biology Technology:Immunovaccine Inc. (TSX: IMV) receives Fast Track and Phase I trial approval for Ebola and Anthrax vaccine programs, signs co-development agreement with Gilead Sciences 2Immunovaccine Inc. (TSX: IMV) receives Fast Track and Phase I trial approval for Ebola and Anthrax vaccine programs, signs co-development agreement with Gilead Sciences 3Cytokinetics Joins Global Movement to Raise Awareness for Rare Diseases 2Cytokinetics Joins Global Movement to Raise Awareness for Rare Diseases 3Cytokinetics Joins Global Movement to Raise Awareness for Rare Diseases 4Cytokinetics Joins Global Movement to Raise Awareness for Rare Diseases 5Cytokinetics Joins Global Movement to Raise Awareness for Rare Diseases 623andMe Appoints Kate Black as Privacy Officer and Corporate Counsel 2DuPont Leader Outlines Path for Growth in Agriculture and Nutrition & Health Segments 2DuPont Leader Outlines Path for Growth in Agriculture and Nutrition & Health Segments 3DuPont Leader Outlines Path for Growth in Agriculture and Nutrition & Health Segments 4DuPont Leader Outlines Path for Growth in Agriculture and Nutrition & Health Segments 5
... a failed terrorist attack in 2006, plane passengers have not ... airports, leaving some parched at the airport and others having ... in Germany is paving the way to eliminate this necessary ... in IOP Publishing,s Superconductor Science and Technology explains ...
... This release is available in German . ... the electromagnetic character of radio waves by Heinrich Hertz, wireless ... are applied to transmit more data within shorter periods of ... also be used for radio transmis-sion. So far, however, manufacture ...
... Inc. (TSX: ONC, NASDAQ: ONCY ) ("Oncolytics") announced ... Canadian Biosciences Corp. (BCBC), a privately held biotechnology company ... of a variety of conditions, including cancer. , Oncolytics ... BCBC in exchange for 200,000 common shares of Oncolytics. ...
Cached Biology Technology:0.2 second test for explosive liquids 2Smallest nanoantennas for high-speed data networks 2Smallest nanoantennas for high-speed data networks 3Oncolytics Biotech(R) Inc. Announces Investment in Private Biotechnology Company 2
... CRF The antibody blocks ... sequence that it was raised ... found in the paraventricular hypothalamic ... colchicine treated 4% FA perfused ...
... siSolutions siRNA Custom Synthesis Service ... duplex RNA to knockdown any ... (19 RNA base pairs with ... 27-mers, or other lengths of ...
... 100 IS System is ideal for developing ... reagents. This system contains the new, improved, ... Luminex. The user can design specific templates ... system has fully integrated graphing and data ...
Polyclonal Antibody to HADHB...
Biology Products: