Navigation Links
FASEB announces 2014 Science Research Conference: Dynamic DNA Structures in Biology
Date:1/29/2014

Bethesda, MD This 2014 FASEB Science Research Conference focuses on dynamic DNA structures. For decades after its discovery, DNA was believed to be a canonical, right-handed double helix. This belief was shaken by the findings that DNA structure is much more dynamic. In fact, DNA can form an enormous variety of secondary structures, including cruciform-like, left-handed helixes, three and four stranded helices, slip-stranded configurations, etc. Most importantly, repetitive DNA sequences, which are overrepresented in genomic DNA, are particularly prone to structural transitions.

Transient denaturation of the double helix, which promotes these dynamic transitions in DNA structure, occurs during all major DNA transactions, including replication, transcription, and recombination. Studies conducted in many labs worldwide have confirmed that structure-prone DNA sequences are central to the normal functioning of the genome, and they are also responsible for its occasional malfunctioning. One striking example is the discovery that expansions of structure-prone DNA repeat leads to more than thirty hereditary neurological and developmental diseases in humans.

Dynamic DNA structures are also involved in regular DNA processes including transcriptional activation, regulation of antigenic switching, and DNA recombination essential to the immune response. DNA structures are associated with recurrent translocations observed in common human cancers, and they also contribute to genomic instability in human hereditary diseases. In an unexpected twist, these DNA structures appeared to be invaluable for nanotechnology, where their unusual physical properties find many applications. These and related topics will be discussed at the conference.


'/>"/>

Contact: Robin Crawford, CMP
src@faseb.org
301-634-7010
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1

Related biology news :

1. FASEB 2013 Excellence in Science Award recipient announced
2. Undergraduate Student Summer Research Award recipients announced for the 2012 FASEB MARC summer research opportunity program
3. FASEB lauds Air India for transporting research animals
4. FASEB urges biomedical research community to speak out against sequestration
5. FASEB SRC announces conference: Gastrointestinal Tract XV: Epithelia, Microbes, Inflammation & Cancer
6. FASEB SRC announces conference registration open: The Biology of Calpains in Health and Disease
7. FASEB SRC announces: Mechanism and Regulation of Prokaryotic Transcription Conference
8. FASEB SRC announces conference: Renal Hemodynamics: Integrating with the Nephron & Beyond
9. FASEB SRC announces conference registration open for: Ciliate Molecular Biology
10. FASEB SRC announces conference registration open for: Mechanisms in Plant Development Conference
11. FASEB SRC announces conference registration open for: Hematologic Malignancies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2016)... 2016 Einzigartige ... und Stimmerkennung mit Passwörtern     ... MESG ), ein führender Anbieter digitaler Kommunikationsdienste, ... SpeechPro zusammenarbeitet, um erstmals dessen Biometrietechnologie einzusetzen. ... Möglichkeit angeboten, im Rahmen mobiler Apps neben ...
(Date:3/21/2016)... March 22, 2016 Unique ... passcodes for superior security   ... provider of secure digital communications services, today announced it ... and offer enterprise customers, particularly those in the Financial ... and voice authentication within a mobile app, alongside, and ...
(Date:3/15/2016)... , March 15, 2016 ... report published by Transparency Market Research "Digital Door Lock Systems ... Forecast 2015 - 2023," the global digital door lock systems ... Mn in 2014 and is forecast to grow at a ... of micro, small and medium enterprises (MSMEs) across the world ...
Breaking Biology News(10 mins):
(Date:5/4/2016)... CA (PRWEB) , ... May 04, 2016 , ... ... Well, look no further than LaJollaCooks4u, San Diego’s premiere hands-on cooking experience. Offering ... need to give mom an experience she won’t forget. , Guests that visit ...
(Date:5/4/2016)... , May 4, 2016  Bayer today ... oncology compound Stivarga ® (regorafenib) tablets for ... (HCC) has met its primary endpoint of a ... called RESORCE, evaluated the efficacy and safety of ... progressed after treatment with sorafenib. The safety and ...
(Date:5/4/2016)... According to a new market ... Global Industry Analysis, Size, Share, Growth, Trends, and Forecast ... expand at a CAGR of 17.1% from 2016 to ... Metabolomics is the extensive study of small molecules, ... organisms. Together, these small molecules and their interactions in ...
(Date:5/4/2016)... ... May 04, 2016 , ... Nutrafol®, a ... help treat hormonal and stress related hair loss. With patent-pending formulas for both ... key opinion leaders in the medical and salon channels nationwide. , Dermatologists, ...
Breaking Biology Technology: