Bethesda, MD The Federation of American Societies for Experimental Biology (FASEB) announces the opening of registration for the Science Research Conference (SRC): NAD Metabolism & Signaling.
In recent years, it has become increasingly clear that NAD and related metabolites are involved in a wide variety of critical biological processes and pathophysiology of various diseases, including type 2 diabetes and other metabolic complications. In the past decade, many unanticipated, exciting discoveries have been made in the field of NAD biology: new NAD-dependent reactions have been discovered (e.g. NAD-dependent protein deacylation by sirtuins), new enzymes and metabolites have been identified (e.g. nicotinamide phosphoribosyltransferase (NAMPT), nicotinamide riboside kinase (NRK), and O-acetyl-ADP-ribose), new NAD biosynthetic pathways have been revealed (e.g. a new pathway starting from nicotinamide riboside), and new intra- and extracellular NAD-dependent signaling pathways have been characterized (e.g. the NAADP signaling pathway, and NAD-induced cell death of immune cells).
These new discoveries have obviously fueled much more enthusiasm on NAD biology to the scientific community than ever, and classic paradigms, in which NAD/NADH and NADP/NADPH are considered just as co-enzymes, are now quickly being transformed into a novel, more comprehensive view of NAD biology. Indeed, reflecting this exciting trend, the number of publications on NAD biology has dramatically increased in these years. The newly developing areas of NAD biology require extensive, interdisciplinary interactions among scientists with diverse expertise including enzymology, structural biology, medicinal/biological chemistry, cell biology, physiology, genetics, many omics, and translational medicine. Therefore, it is essential to bring those scientists together to a comprehensive, interdisciplinarily organized meeting and fully discuss these cutting-edge fronts of NAD bio
|Contact: Robin Crawford|
Federation of American Societies for Experimental Biology