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Extreme morning sickness could lead to lifelong emotional, behavioral disorders in kids
Date:8/23/2011

An extreme form of pregnancy-related nausea and vomiting known as hyperemesis gravidarum (HG) takes a heavy toll on thousands of women each year and can lead to hospitalization and pregnancy termination. But new research suggests pregnant women are not the only victims.

A joint study by UCLA and the University of Southern California has found that children whose mothers suffered from HG while carrying them were 3.6 times more likely to suffer from anxiety, bipolar disorder and depression in adulthood than individuals whose mothers did not have the condition. HG sends some 285,000 women to the hospital in the U.S. each year.

The study is published in the August 2011 issue of the Journal of Developmental Origins of Health and Disease.

Prior studies have found that children of women who experience nausea persisting beyond the first trimester of pregnancy have more attention and learning problems by age 12, said study co-author Marlena Fejzo, an assistant professor of hematologyoncology at the David Geffen School of Medicine at UCLA and an assistant professor of maternal and fetal medicine at the Keck School of Medicine of USC. And other studies have found that poor fetal nutrition, a frequent result of HG, can lead to poor health in adulthood.

"Even though hyperemesis gravidarum can be a form of starvation and dehydration in pregnancy, no studies prior to this have been done to determine the long-term effects it has on the exposed unborn child," Fejzo said.

HG often runs in families and in previous research, Fejzo and her colleagues found that women with a family history of the condition were up to 17 times more likely to suffer from it themselves.

The findings from the current study were based on surveys of women with HG who reported on the emotional and behavioral histories of their siblings. Of the 150 respondents, 55 had mothers who also suffered from the condition, so their siblings wer
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Contact: Enrique Rivero
erivero@mednet.ucla.edu
310-794-2273
University of California - Los Angeles Health Sciences
Source:Eurekalert

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