Navigation Links
Extract of broccoli sprouts may protect against bladder cancer
Date:2/27/2008

PHILADELPHIA A concentrated extract of freeze dried broccoli sprouts cut development of bladder tumors in an animal model by more than half, according to a report in the March 1 issue of Cancer Research, a journal of the American Association for Cancer Research.

This finding reinforces human epidemiologic studies that have suggested that eating cruciferous vegetables like broccoli is associated with reduced risk for bladder cancer, according to the studys senior investigator, Yuesheng Zhang, MD, PhD, professor of oncology at Roswell Park Cancer Institute. Although this is an animal study, it provides potent evidence that eating vegetables is beneficial in bladder cancer prevention, he said.

There is strong evidence that the protective action of cruciferous vegetables derives at least in part from isothyiocyanates (ITCs), a group of phytochemicals with well-known cancer preventive activities.The bladder is particularly responsive to this group of natural chemicals, Zhang said. In our experiments, the broccoli sprout ITCs after oral administration were selectively delivered to the bladder tissues through urinary excretion.

Other cruciferous vegetables with ITCs include mature broccoli, cabbage, kale, collard greens and others. Broccoli sprouts have approximately 30 times more ITCs than mature broccoli, and the sprout extract used by the researchers contains approximately 600 times as much.

Although animals that had the most protection against development of bladder cancer were given high doses of the extract, Zhang said humans at increased risk for this cancer likely do not need to eat huge amounts of broccoli sprouts in order to derive protective benefits.

Epidemiologic studies have shown that dietary ITCs and cruciferous vegetable intake are inversely associated with bladder cancer risk in humans. It is possible that ITC doses much lower than those given to the rats in this study may be adequate for bladder can
'/>"/>

Contact: Jeremy Moore
Jeremy.moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

Page: 1 2

Related biology news :

1. Bilberry extract -- can it help prevent certain cancers?
2. Videos extract mechanical properties of liquid-gel interfaces
3. A compound extracted from olives inhibits cancer cells growth and prevents their appearance
4. Natural chemical found in broccoli helps combat skin blistering disease
5. Natural compound in broccoli could treat devastating genetic skin disorder
6. Eat up all of your Brussels sprouts -- unless youre an aphid
7. Rain forest protection works in Peru
8. Same gene protects from 1 disease, opens door to another
9. Conservation International and Toyota partner to protect Philippines rain forests
10. Fungus genome yielding answers to protect grains, people and animals
11. Genes that both extend life and protect against cancer identified
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/27/2015)... ATLANTA , April 27, 2015  For more ... and trade show has been the premier worldwide event ... Systems 2015 is a must-attend event for any local, ... insight into the emerging commercial markets and current applications ... and innovations of this projected $48 billion industry, and ...
(Date:4/20/2015)... The announcement comes as demand for fire vault ... Ireland,s foremost records management company, has secured ... impressive track record of clients within the first 12 months, ... sector in Dubai . As a result, ... a further eight staff members at its Irish headquarters. The ...
(Date:4/13/2015)... , April 13, 2015  higi, a leading ... ways to more fully engage with their communities around ... industry-leading, privacy protected and secure API.  ... enables the most accessible, affordable, and convenient vehicle to ... The API will allow ...
Breaking Biology News(10 mins):UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 2UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 3UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 4UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 5Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 2Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 3higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 2higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 3
... by St. Jude Children,s Research Hospital scientists has identified ... targeting an innate immune system component in a bid ... researchers demonstrated that the primary function of one of ... in turn dampens the immune response to infections and ...
... -- Researchers at Georgetown Lombardi Comprehensive Cancer Center have ... determinant of resistance to anti-estrogen therapy used to treat ... the July 1 issue of Cancer Research , ... breast cells undergo stress induced by the agents tamoxifen ...
... month,s Physics World, Steve Haake, director of the Centre for ... that the men,s 100 m sprint will be one event ... called the "performance-improvement index", which uses very simple physics to ... over the last 100 years. The model shows that ...
Cached Biology News:Innate immune system protein provides a new target in war against bacterial infections 2Innate immune system protein provides a new target in war against bacterial infections 3Single protein promotes resistance to widely used anti-estrogen drugs 2Single protein promotes resistance to widely used anti-estrogen drugs 3Physics confirms sprinters are performing better than ever before 2
(Date:5/28/2015)... May 28, 2015 The Academy of Model ... Aviation Day on August 15, 2015. National Model Aviation Day ... and to introduce model flying to the general public. , ... clubs to participate in the celebration by hosting events in ... host National Model Aviation Day events. View our online ...
(Date:5/28/2015)... CARLOS, Calif. , May 28, 2015 /PRNewswire/ ... testing, today announced a study published in ... the Panorama single-nucleotide polymorphism (SNP)-based non-invasive prenatal test ... the first trimester. A study ... that complete molar pregnancies occur in about 1 ...
(Date:5/28/2015)... May 28, 2015 BioNorth Texas ... and representing the life sciences industry in northern ... Directors meeting at The Foundry in Dallas on ... organization brought together a broad spectrum of biotech ... the organization's early successes in partnering with key ...
(Date:5/28/2015)... Mass. , May 28, 2015 RXi ... focused on discovering and developing innovative therapeutics, primarily in ... pricing of a public offering of 26 million units ... share for gross proceeds of approximately $10.4 million. Each ... (ii) a 13-month overallotment purchase right to purchase 0.50 ...
Breaking Biology Technology:Model flying pilots celebrate the Academy of Model Aeronautics Foundation’s Third Annual National Model Aviation Day 2First Confirmed Detection of a Complete Molar Pregnancy with Cell-Free DNA Test 2First Confirmed Detection of a Complete Molar Pregnancy with Cell-Free DNA Test 3BioNorthTX Holds Inaugural Board of Directors Meeting 2BioNorthTX Holds Inaugural Board of Directors Meeting 3RXi Pharmaceuticals Announces $10 Million Public Offering of Common Stock and Warrants 2RXi Pharmaceuticals Announces $10 Million Public Offering of Common Stock and Warrants 3
... 2011 PharmAthene, Inc. (NYSE Amex: PIP ... and chemical threats, today announced the appointment of Brian ... September 22, 2011. Mr. Markison was recently ... Officer for Nycomed U.S. which will be spun out from the ...
... Inc., a biopharmaceutical company focused on the development of ... today that it presented positive results from a Phase ... severe chronic obstructive pulmonary disease (COPD), a large and ... the annual meeting of the European Respiratory Society (ERS). ...
... - Clean solutions to human energy demands are essential to ... energy at our disposal, we have yet to learn how ... to University of Toronto chemistry professor Greg Scholes, the answers ... nature. "Solar fuel production often starts with the energy ...
Cached Biology Technology:PharmAthene Appoints Brian A. Markison to the Company's Board of Directors 2PharmAthene Appoints Brian A. Markison to the Company's Board of Directors 3Elevation Pharmaceuticals Presents Positive Phase 2a Results in COPD Patients at the European Respiratory Society Annual Congress 2Elevation Pharmaceuticals Presents Positive Phase 2a Results in COPD Patients at the European Respiratory Society Annual Congress 3Elevation Pharmaceuticals Presents Positive Phase 2a Results in COPD Patients at the European Respiratory Society Annual Congress 4Elevation Pharmaceuticals Presents Positive Phase 2a Results in COPD Patients at the European Respiratory Society Annual Congress 5Nature offers key lessons on harvesting solar power, says U of T chemistry professor 2
... siRNA while maintaining high cell viability ... simultaneously , Fast: less than ... incubation , Highly reproducible results ... use with the Bio-Rad Gene Pulser Xcell ...
100 adhesive strips....
Request Info...
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
Biology Products: