Navigation Links
Exposure to secondhand smoke in the womb has lifelong impact
Date:6/30/2010

PITTSBURGH, June 30 Newborns of non-smoking moms exposed to secondhand smoke during pregnancy have genetic mutations that may affect long-term health, according to a University of Pittsburgh Graduate School of Public Health study published online in the Open Pediatric Medicine Journal. The abnormalities, which were indistinguishable from those found in newborns of mothers who were active smokers, may affect survival, birth weight and lifelong susceptibility to diseases like cancer.

The study confirms previous research in which study author Stephen G. Grant, Ph.D., associate professor of environmental and occupational health at Pitt's Graduate School of Public Health, discovered evidence of abnormalities in the HPRT gene located on the X chromosome in cord blood from newborns of non-smokers exposed to environmental tobacco smoke.

In the current study, Dr. Grant confirmed smoke-induced mutation in another gene called glycophorin A, or GPA, that is representative of oncogenes genes that transform normal cells into cancer cells and cause solid tumors. The GPA mutation was the same level and type in newborns of mothers who were active smokers and of non-smoking mothers exposed to tobacco smoke. Likewise, the mutations were discernable in newborns of women who had stopped smoking during their pregnancies, but who did not actively avoid secondhand smoke.

"These findings back up our previous conclusion that passive, or secondary, smoke causes permanent genetic damage in newborns that is very similar to the damage caused by active smoking," said Dr. Grant. "By using a different assay, we were able to pick up a completely distinct yet equally important type of genetic mutation that is likely to persist throughout a child's lifetime. Pregnant women should not only stop smoking, but be aware of their exposure to tobacco smoke from other family members, work and social situations."


'/>"/>

Contact: Clare Collins
CollCX@upmc.edu
412-648-9725
University of Pittsburgh Schools of the Health Sciences
Source:Eurekalert

Page: 1

Related biology news :

1. Meth exposure in young adults leads to long-term behavioral consequences
2. UCR engineers to develop new tool to measure how environmental exposures affect health
3. Researchers developing device to predict proper light exposure for human health
4. Nanoparticle exposures happen, says expert
5. Time spent in car drives up air pollution exposure
6. MIT: Prenatal arsenic exposure detected in newborns
7. Moderate prenatal exposure to alcohol and stress in monkeys can cause touch sensitivity
8. Low exposure to asbestos-like mineral from Montana vermiculite may up lung disease risk
9. Exposure to low levels of radon appears to reduce the risk of lung cancer, new study finds
10. Early exposure to common weed killer impairs amphibian development
11. OSU study shows exposure to bad air raises blood pressure
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/15/2014)... allow us to better understand how the fish ... and provide the type of environmental data to ... siting of protected areas," said Paula Whitfield, a ... Ocean Science (NCCOS) and lead author of the ... the temperate-tropical transition zone, where historically, both temperate ...
(Date:9/15/2014)... 500 million years after it formed may have been ... continents and active crustal plates. , This alternate view ... gained substantial new support from the first detailed comparison ... years ago with those formed contemporaneously in Iceland, which ... early Earth. , The study was conducted by a ...
(Date:9/15/2014)... hearing and cognitive function may play roles in one,s ... rhythm, pitch, timbre, tone durations, and formal structure in ... article explain that extremes in musical aptitude (extreme capacity/no ... of individuals having moderate aptitude. , "This is a ... underlying genes, and it is influenced to varying degrees ...
Breaking Biology News(10 mins):Study finds warming Atlantic temperatures could increase range of invasive species 2Early Earth less hellish than previously thought 2Early Earth less hellish than previously thought 3
... ovarian ,chocolate, cysts for the brown liquid they contain, ... common, which can cause ongoing pain and complications. A ... and effective remedy the oral contraceptive pill (OCP). ... Reilly from Auckland, New Zealand, highlight a trial published ...
... AUGUSTA, Ga. - New drugs that are helping fight ... cardiovascular disease, Medical College of Georgia researchers said. Cancer ... as a cause. Heat shock protein 90 inhibitors as a ... director of MCG,s Vascular Biology Center. "I think hsp90 ...
... use of Chinese wolfberries to improve vision deficiencies that are ... assistant professor of human nutrition, is studying wolfberries and their ... that the fruit can lower the oxidative stress that the ... would not say that wolfberries are a medicine, but they ...
Cached Biology News:New cancer therapy may fight cardiovascular disease 2Study uses Chinese wolfberries to improve vision imperfections caused by type-2 diabetes 2Study uses Chinese wolfberries to improve vision imperfections caused by type-2 diabetes 3
(Date:9/16/2014)...  LABSCO, the leading specialty sales agent of ... office laboratories and alternate healthcare settings is proud ... will serve as Siemens Healthcare Diagnostics, exclusive sales ... a semi-exclusive sales distributor in specified POL market ... States . LABSCO will be responsible for ...
(Date:9/16/2014)... Canada (PRWEB) September 16, 2014 According ... the Toronto affiliate of ITRA Global, new development in ... the Toronto city council approving another 755 storeys of ... it appears construction cranes will be dominating the Toronto ... seems to have an unquenchable thirst for new development. ...
(Date:9/15/2014)... EnGeneIC, Ltd. , an emerging ... cancer through the targeted delivery of therapeutic agents ... the Asbestos Disease Research Institute (ADRI), it has ... (NSW) Premier,s Award for Excellence in Translational Cancer ... that will be involved in the clinical trial, ...
(Date:9/15/2014)... researchers led by Northeastern University has developed a ... and a variety of nanocarbon structures in carbon ... scalable, which will allow the researchers to tailor ... in applications ranging from electronic devices to CNT-reinforced ... sports equipment. , Their findings were published in ...
Breaking Biology Technology:LABSCO Secures Alliance With Siemens Healthcare Diagnostics 2LABSCO Secures Alliance With Siemens Healthcare Diagnostics 3ITRA Global Reports Downtown Toronto Real Estate Development is in High Gear 2ITRA Global Reports Downtown Toronto Real Estate Development is in High Gear 3EnGeneIC Named a Recipient of the Cancer Institute NSW Premier's Award for Excellence in Translational Cancer Research 2EnGeneIC Named a Recipient of the Cancer Institute NSW Premier's Award for Excellence in Translational Cancer Research 3Northeastern University Researchers Develop Novel Method for Working with Nanotubes 2
... , SANTA CLARA, Calif. , Jan. 28 Coherent, Inc. (Nasdaq: COHR ), a world leader in providing ... , FINANCIAL HIGHLIGHTS , , , , , ... Three Months Ended, ... ------------------, GAAP Results ...
... , MADRID , Jan. 28 The ... category goes to physicist and chemist Richard N. Zare , ... , of the University of Maryland , for their independent, ... unraveled secrets of nature,s building blocks and the underlying interactions between ...
... ... Webster Cavenee, Ph.D., and Frank Furnari, Ph.D., along with their team at ... Diego School of Medicine, have recently discovered one way that brain tumors ... stop tumor growth. This breakthrough discovery revealed a new cellular mechanism ...
Cached Biology Technology:Coherent, Inc. Reports Strong First Fiscal Quarter Results and Raises Annual Sales Guidance 2Coherent, Inc. Reports Strong First Fiscal Quarter Results and Raises Annual Sales Guidance 3Coherent, Inc. Reports Strong First Fiscal Quarter Results and Raises Annual Sales Guidance 4Coherent, Inc. Reports Strong First Fiscal Quarter Results and Raises Annual Sales Guidance 5Coherent, Inc. Reports Strong First Fiscal Quarter Results and Raises Annual Sales Guidance 6Coherent, Inc. Reports Strong First Fiscal Quarter Results and Raises Annual Sales Guidance 7Coherent, Inc. Reports Strong First Fiscal Quarter Results and Raises Annual Sales Guidance 8Coherent, Inc. Reports Strong First Fiscal Quarter Results and Raises Annual Sales Guidance 9Coherent, Inc. Reports Strong First Fiscal Quarter Results and Raises Annual Sales Guidance 10Coherent, Inc. Reports Strong First Fiscal Quarter Results and Raises Annual Sales Guidance 11Coherent, Inc. Reports Strong First Fiscal Quarter Results and Raises Annual Sales Guidance 12Zare and Fisher Win the BBVA Foundation Frontiers of Knowledge Award in Basic Sciences for Rendering Molecules Visible and Analyzing Their Collective Behavior 2Zare and Fisher Win the BBVA Foundation Frontiers of Knowledge Award in Basic Sciences for Rendering Molecules Visible and Analyzing Their Collective Behavior 3Zare and Fisher Win the BBVA Foundation Frontiers of Knowledge Award in Basic Sciences for Rendering Molecules Visible and Analyzing Their Collective Behavior 4Zare and Fisher Win the BBVA Foundation Frontiers of Knowledge Award in Basic Sciences for Rendering Molecules Visible and Analyzing Their Collective Behavior 5Zare and Fisher Win the BBVA Foundation Frontiers of Knowledge Award in Basic Sciences for Rendering Molecules Visible and Analyzing Their Collective Behavior 6Zare and Fisher Win the BBVA Foundation Frontiers of Knowledge Award in Basic Sciences for Rendering Molecules Visible and Analyzing Their Collective Behavior 7NFCR Scientists Discover Brain Tumor's “Escape Path” 2NFCR Scientists Discover Brain Tumor's “Escape Path” 3
... custom siRNA service provides the premium quality ... research. Custom siRNAs can be readily ordered ... target sequence, or by providing the sense ... Ambion's Silencer Validated and Silencer Pre-designed siRNAs, ...
... Ambion's custom siRNA service provides the premium ... silencing research. Custom siRNAs can be readily ... base target sequence, or by providing the ... out Ambion's Silencer Validated and ...
Human SDNSF/MCFD2 Biotinylated Affinity Purified PAb...
Recombinant Ovine (Sheep) Prolactin, Ultra Pure...
Biology Products: