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Exposure to Agent Orange linked to prostate cancer in Vietnam veterans
Date:8/5/2008

were nearly four times more likely to present with metastatic disease. Other prostate cancer risk factors race, body-mass index and smoking were not statistically different between the two groups.

"Our country's veterans deserve the best possible health care, and this study clearly confirms that Agent Orange exposure during service in Vietnam is associated with a higher risk of prostate cancer later in life," said Ralph deVere White, UC Davis Cancer Center director and a study co-author. "Just as those with a family history of prostate cancer or who are of African-American heritage are screened more frequently, so too should men with Agent Orange exposure be given priority consideration for all the screening and diagnostic tools we have at our disposal in the hopes of early detection and treatment of this disease."

Now a banned chemical, Agent Orange is a combination of two synthetic compounds known to be contaminated with the dioxin tetrachlorodibenzo-para-dioxin (TCDD) during the manufacturing process. Named for the color of the barrel in which it was stored, Agent Orange was one of many broad-leaf defoliants used in Vietnam to destroy dense forests in order to better visualize enemy activity.

It is estimated that more than 20 million gallons of the chemicals, also known as "rainbow herbicides," were sprayed between 1962 and 1971, contaminating both ground cover and ground troops. Most of the rainbow herbicide used during this time was Agent Orange. In 1997, the International Agency for Research on Cancer reclassified TCDD as a group 1 carcinogen, a classification that includes arsenic, asbestos and gamma radiation.


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Contact: Karen Finney
karen.finney@ucdmc.ucdavis.edu
916-734-9064
University of California - Davis - Health System
Source:Eurekalert

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