Navigation Links
Expert insights on in vitro alternatives for drug and chemical toxicity testing
Date:8/7/2014

New Rochelle, NY, August 7, 2014In vitro toxicity testing is rapidly being adopted in the pharmaceutical, chemical, and cosmetics industries, for example, as an alternative to animal studies to predict adverse health effects of drugs and personal care products and the health consequences of environmental exposures. An insightful Roundtable Discussion focused on how to apply these novel toxicology models to everyday hazard prediction, risk assessment, and decision making in industry is published in the preview issue of the new journal Applied In Vitro Toxicology, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers. The article is available free on the Applied In Vitro Toxicology website.

In the Roundtable Discussion "Comments on How to Make the New Vision of Toxicity Testing in the 21st Century a Reality," Moderator Jim McKim, Editor-in-Chief of Applied In Vitro Toxicology and Founder and CEO, IONTOX, LLC, challenges the panelists to present a realistic view of how far the field has advanced in implementing the strategy put forth in a National Academy of Sciences report to improve toxicity testing.

Panelists Alan Goldberg, Consulting Editor of the Journal, Nicole Kleinstreuer, ILS/National Toxicology Program Interagency Center for Evaluation of Alternative Toxicological Methods (Research Triangle Park, NC), Francois Busquet, Center for Alternatives to Animal Testing (Konstanz, Germany), and Melvin Andersen, The Hamner Institutes for Health Sciences (RTP, NC) participate in an interactive discussion on the use of human cell models combined with high-throughput screening methods to test for toxicity, and the complexity of applying adverse outcome pathways (AOPs). The conversation covers topics ranging from policy issues, challenges related to data interpretation and understanding the information gained from in vitro models, the emergence of three-dimensional tissue culture models that integrate cells from multiple human organs, and the different approaches being used to assess risk from high-dose, short-term exposures compared to exposure to lower concentrations of a chemical over longer periods of time.

"Improved analytical technologies and improvements in human tissue models will allow us to change the animal safety testing paradigm," says Jim McKim.


'/>"/>

Contact: Kathryn Ryan
kryan@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Related biology news :

1. Experts Weigh the Pros and Cons of a $1.7 Billion EPA Cleanup Plan for the Passaic River at an NJIT
2. Experts voice concerns over arsenic in rice, reports Journal of Pediatric Gastroenterology and Nutrition
3. Top aging research experts to present at 43rd Annual American Aging Association Conference
4. Solar energy prospects are bright for Scotland, experts say
5. CHOP expert Dr. Garrett Brodeur honored for career work in neuroblastoma
6. MIPT experts reveal the secret of radiation vulnerability
7. Control methane now, greenhouse gas expert warns
8. Wildlife response to climate change is likely underestimated, experts warn
9. International research group recognizes UTMB experts
10. Experts disagree on horses with incoordination
11. The metrology experts of the future come from Braunschweig
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Expert insights on in vitro alternatives for drug and chemical toxicity testing
(Date:5/3/2016)... 2016  Neurotechnology, a provider of high-precision biometric ... Biometric Identification System (ABIS) , a complete system ... ABIS can process multiple complex biometric transactions with ... fingerprint, face or iris biometrics. It leverages the ... MegaMatcher Accelerator , which have been used ...
(Date:4/28/2016)... -- First quarter 2016:   , Revenues ... first quarter of 2015 The gross margin was 49% ... and the operating margin was 40% (-13) Earnings per ... from operations was SEK 249.9 M (21.2) , Outlook ... 7,000-8,500 M. The operating margin for 2016 is estimated ...
(Date:4/26/2016)... , April 27, 2016 ... the  "Global Multi-modal Biometrics Market 2016-2020"  report to ... ) , The analysts forecast the ... CAGR of 15.49% during the period 2016-2020.  ... number of sectors such as the healthcare, BFSI, ...
Breaking Biology News(10 mins):
(Date:5/26/2016)... San Diego, CA (PRWEB) , ... May 26, ... ... assay development and manufacturing company, today announced several positive developments that position the ... As a result of the transaction, Craig F. Kinghorn has been appointed ...
(Date:5/25/2016)... ... May 25, 2016 , ... Founder of the Fitzmaurice Hand ... and surgery of the hand by the National Board of Physicians and Surgeons, ... and beyond in his pursuit of providing the most comprehensive, effective treatment for ...
(Date:5/25/2016)... ... May 25, 2016 , ... Biohaven Pharmaceutical Holding Company ... granted the company’s orphan drug designation request covering BHV-4157 for the treatment of ... the FDA. , Spinocerebellar ataxia is a rare, debilitating neurodegenerative disorder that ...
(Date:5/23/2016)... ... May 23, 2016 , ... The need for blood donations in South Texas and across ... South Texas Blood & Tissue Center, blood donations are on the decline. In fact, donations ... are down 21 percent in South Texas in the last four years alone. , There ...
Breaking Biology Technology: