Navigation Links
Experiment finds ulcer bug's Achilles' heel
Date:12/10/2012

arranged.

The challenge with membrane proteins is that they are especially hard to grow good quality crystals of, and for this experiment, said Luecke, "We needed to grow and screen thousands of crystals."

"We collected over 100 separate data sets and tried numerous structural determination techniques," said Mike Soltis, head of SSRL's Structural Molecular Biology division, who worked with Luecke and his team to create the 3-D map of the atomic structure. The final data set was measured at SSRL's highest brightness beam line (12-2), which produced the critical data that met the challenge.

"This is the hardest structure I've ever deciphered, and I've been doing this since 1984," Luecke said. "You have to try all kinds of tricks, and these crystals fought us every step of the way. But now that we have the structure, we've reached the exciting partthe prospect of creating specific, safe and effective ways to target this pathogen and wipe it out."


'/>"/>

Contact: Andy Freeberg
afreeberg@slac.stanford.edu
650-926-4359
DOE/SLAC National Accelerator Laboratory
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Experiments may understate plant responses to climate
2. Foundational concept of ecology tested by experiment
3. Nicole George wins 2012 Journal of Experimental Biology Outstanding Paper Prize
4. MIT research: Study finds room to store CO2 underground
5. Study finds circle hooks lower catch rate for offshore anglers
6. LSUHSC research finds HPV-related head & neck cancers rising, highest in middle-aged white men
7. Head and body lice appear to be the same species, genetic study finds
8. Study finds peoples niceness may reside in their genes
9. Large international study finds memory in adults impacted by versions of 4 genes
10. Improved loblolly pines better for the environment, study finds
11. NIST/UMass study finds evidence nanoparticles may increase plant DNA damage
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Experiment finds ulcer bug's Achilles' heel
(Date:7/21/2015)... Connecticut , July 21, 2015  NXT-ID, ... "Company"), a biometric authentication company focused on the ... Wocket® smart wallet, announces that it has filed ... System and Method. This invention ... not only authorizes an account, but also the ...
(Date:7/13/2015)... July 13, 2015 Synaptics Inc. (NASDAQ: ... interface solutions, today announced sampling of ClearPad ® ... driver integration (TDDI) product targeting smartphones and tablets. ... combine Synaptics , best-in-class touch controller IP ... technology developed in the company,s Japan Design Center. ...
(Date:7/9/2015)... Research and Markets( ... "Biometrics for Banking; Market & Technology Analysis, ... their offering. The adoption for banking ... and the forecast is that by 2020 it ... involved in delivering biometric systems to the banking ...
Breaking Biology News(10 mins):NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 2NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 3NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 4Synaptics Announces Sampling of Second Generation TDDI Solutions 2Synaptics Announces Sampling of Second Generation TDDI Solutions 3Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 2Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 3
... Oregon Health & Science University (OHSU) and Legacy Health ... useable in standard diabetes pumps. Such a formulation could ... in people with type 1 diabetes (T1D) who are ... to future-generation artificial pancreas systems that dispense more than ...
... stagnated for over twenty years. That is the main conclusion ... University of Groningen into this type of prosthesis, which is ... Development . High operating force , The ... and the University of Groningen, measured the force required to ...
... news in one setting might spell disaster in another. In ... grow and divide without restraint, it,s a welcome message for ... harbors this cell in his or her body. Weizmann Institute ... molecular message that prompts unbridled cellular growth. The molecular ...
Cached Biology News:Liquid glucagon formulation discovered for potential use in artificial pancreas systems 2Development of prosthetic hands stagnated for 20 years 2Kill the messenger 2
(Date:7/30/2015)... Kan. , July 30, 2015   ... a pet therapeutics company focused on the licensing, ... companion animals, today announced that its strategic partner ... a dose confirmation study of AT-016, an adipose-derived ... for the treatment of osteoarthritis pain in dogs. ...
(Date:7/30/2015)... 30, 2015 Ascendis Pharma A/S (Nasdaq: ... its innovative TransCon technology to address significant unmet ... a six-month Phase 2 study to evaluate the ... in 53 treatment-naïve, pre-pubertal children with growth hormone ... pleased with the top-line results from our Phase ...
(Date:7/30/2015)... ... 30, 2015 , ... As part of its 2015 growth plan and as a follow up ... business units, Whitehouse Laboratories is pleased to announce that it has begun construction on ... of Excellence and will be strictly dedicated to basic USP 51, USP 61, and USP ...
(Date:7/29/2015)... PARIS , July 30, 2015 ... de la santé, publie ses résultats pour le ... Brandicourt commente les résultats. Visionner ... http://www.eurobusinessmedia.com/ceo-direct/sanofi/sanofi-h1-2015-results-interview-with-ceo-olivier-brandicourt?utm_source=ceo-direct&utm_medium=wire Au sommaire ... - Moteurs de croissance ...
Breaking Biology Technology:Aratana Therapeutics Announces Positive Pilot Field Study for AT-016 2Aratana Therapeutics Announces Positive Pilot Field Study for AT-016 3Aratana Therapeutics Announces Positive Pilot Field Study for AT-016 4Aratana Therapeutics Announces Positive Pilot Field Study for AT-016 5Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 2Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 3Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 4Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 5Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 6Ascendis Pharma A/S Announces Positive Top-line Results from a Phase 2 Pediatric Study of Once-Weekly TransCon Growth Hormone for the Treatment of Growth Hormone Deficiency 7Whitehouse Labs Formally Announces Plans to Open a Microbiological Laboratory 2
... May 8 Exelixis,Inc. (Nasdaq: EXEL ) announced ... officer of Exelixis, will present at the Bank of,America ... PT on,Tuesday, May 13, 2008. Dr. Scangos will discuss ... The presentation will be webcast and may be accessed ...
... 8 Informed Clinical Sciences (ICS) Advisory,Services ... company,s three-part,Intellectual Property (IP) platform. This Platform ... Informatics Review, an Alliance Business,Review, and a ... the sciences,business concerns, and enabling technologies underlying ...
... Also Announces CE Mark Approval for First Product, the CorMatrix ... ECM(TM) ... Inc., an,Atlanta- based company dedicated to developing and delivering unique,extracellular ... repair damaged cardiovascular tissue, announced,today that the company has received ...
Cached Biology Technology:IC Sciences Announces Launch of ICS Advisory Services Intellectual Property Platforms Available Through ICSciences Alliance 2IC Sciences Announces Launch of ICS Advisory Services Intellectual Property Platforms Available Through ICSciences Alliance 3CorMatrix(R) Announces FDA 510(k) for Novel Biomaterial Implant for Intracardiac Repair 2CorMatrix(R) Announces FDA 510(k) for Novel Biomaterial Implant for Intracardiac Repair 3CorMatrix(R) Announces FDA 510(k) for Novel Biomaterial Implant for Intracardiac Repair 4
... This book is unique in that ... techniques currently used in the diagnosis ... virus-specific antibodies and clinical virus isolates. ... blotting and hybridization procedures, PCR for ...
...
... PureLink PCR Purification Kits provide rapid ... enzymes, short-failed PCR products, and salts from ... bind/wash/elute procedure:, provides two Binding Buffer ... bp* , can be performed in either ...
... Zero Blunt TOPO PCR Cloning Kit ... for high-efficiency (>=95%) cloning of blunt-end ... polymerases. The kit includes the linearized ... for 5-minute bench-top ligations without ligase ...
Biology Products: