Navigation Links
Exercise trumps creatine in cardiac rehab
Date:6/22/2010

London (June 23, 2010) Athletes have been enjoying the benefits of creatine supplements to gain stronger muscles since the 1990s, and the supplement has also proven beneficial among other groups. Could it help cardiac patients regain strength to help with their heart-training workouts as part of rehabilitation? The evidence at this stage suggests not - exercise alone proved a far more powerful tonic for patients in a study out today. The results appear in the journal Clinical Rehabilitation, published by SAGE.

Drs Cornelissen and Defoor along with colleagues created a double blinded, randomised placebo controlled trial to test the effects of creatine supplements used alongside an exercise programme. The study focused on patients with coronary artery disease or chronic heart failure over a three-month period.

Creatine is found naturally in our diets, in particular in meat. Creatine is also produced naturally in the human body for use by muscles; skeletal muscles use the vast majority. The remainder is used in the brain and heart. Supplements improve muscle strength, particularly for short-term, high-intensity exercise, and are used by athletes to make their training more effective. It may also help with muscle weakness due to atrophy in a number of clinical conditions.

Previous studies have shown that chronic heart failure patients' skeletal muscle strength can be improved with creatine supplements giving better strength and endurance in cycle ergomotry tests (on a stationary, gym-style bicycle). Cornelissen and Defoor wanted to find out whether creatine would help with cardiorespiratory endurance, muscle strength and endurance during a cardiac rehabilitation programme, too. They reasoned that test results for older patients and cardiac patients may are likely to be lower due primarily to peripheral muscle weakness, and so giving these muscles a creatine boost may lead to more effective rehabilitation fitness results.

As well as measuring aerobic power, strength, endurance and recovery, the researchers looked at patients' quality of life scores and checked they were taking the supplements or placebos according to schedule. The bottom line was that among the 80 patients in the study, the researchers found no significant differences between the two groups.

"Contrary to our hypothesis, the magnitude of increase in muscle strength and/or endurance was not greater in the group with creatine supplementation," said study supervisor, Professor Luc Vanhees.

The rehabilitation programme led to better leg strength, and endurance and recovery and VO2 peak were significantly higher than when patients started. It may be the case that the large effect of the exercise training covered up any smaller effect that was down to the creatine. The researchers also think it is worth considering a therapeutic role for creatine once cardiac patients are already well established with their rehabilitation programme, as it may further boost their performance and let them get past the 'training hump,' although further study is needed to test this hypotheses.


'/>"/>

Contact: Jayne Fairley
jayne.fairley@sagepub.co.uk
020-732-48719
SAGE Publications UK
Source:Eurekalert

Related biology news :

1. Chocolate milk is a natural for post-exercise recovery
2. Muscle mass in elderly boosted by combining resistance exercise and blood flow restriction
3. Vigorous exercise strengthens hip bones in young children
4. Regular aerobic exercise is good for the brain, Pitt team says
5. Exercise therapy for low back pain
6. For osteoporosis patients, exercise pill one step closer to reality
7. Mental health providers should prescribe exercise more often for depression, anxiety
8. The new exercise HIT: do less
9. Exercise counters negative effects of weight regain, researchers find
10. What you eat after exercise matters
11. UB specialized exercise regimen shown to relieve prolonged concussion symptoms
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/16/2017)... 16, 2017  Genos, a community for personal ... has received Laboratory Accreditation from the College of ... to laboratories that meet stringent requirements around quality, ... processes. "Genos is committed to maintaining ... We,re honored to be receiving CAP accreditation," said ...
(Date:2/10/2017)... Research and Markets has announced ... - Scientific and Commercial Aspects" to their offering. ... Biomarkers ... with therapy for selection of treatment as well for monitoring ... of disease in modern medicine. Biochip/microarray technologies and next generation ...
(Date:2/8/2017)... NEW YORK , Feb. 7, 2017 Report ... ... and should reach $11.4 billion by 2021, growing at a ... Report Includes - An overview of the global markets for ... from 2015, estimates for 2016, and projections of compound annual ...
Breaking Biology News(10 mins):
(Date:2/24/2017)... , Feb. 24, 2017  OncoSec Medical Incorporated ("OncoSec") ... will host a Key Opinion Leader event to highlight ... oral and poster presentation at the upcoming 2017 ASCO-SITC ... KOL event will be held in-person and via live ... / 9:00 AM PST at the Lotte New York ...
(Date:2/23/2017)... TORONTO , Feb. 23, 2017 /PRNewswire/ - The ... Institute for Cancer Research (OICR) are pleased to report ... Series A financing, with Johnson & Johnson Innovation – ... investors include venture groups HealthCap, TPG Biotechnology Partners, and ... ...
(Date:2/23/2017)... Minn. , Feb. 23, 2017  Imanis ... new product line of oncolytic vaccinia viruses for ... Corporation as part of Genelux,s proprietary, vaccinia virus-based ... are excited to enter into a partnership with ... selected oncolytic vaccinia viruses for use in research," ...
(Date:2/23/2017)... ... February 23, 2017 , ... Today, researchers can ... adiponectin, uric acid, and/or other biomarkers or SNPs of interest) using one, easy-to-collect ... SalivaLab , the relationship between insulin and other relevant biomarkers can be extensively ...
Breaking Biology Technology: