Navigation Links
Exercise trumps creatine in cardiac rehab

London (June 23, 2010) Athletes have been enjoying the benefits of creatine supplements to gain stronger muscles since the 1990s, and the supplement has also proven beneficial among other groups. Could it help cardiac patients regain strength to help with their heart-training workouts as part of rehabilitation? The evidence at this stage suggests not - exercise alone proved a far more powerful tonic for patients in a study out today. The results appear in the journal Clinical Rehabilitation, published by SAGE.

Drs Cornelissen and Defoor along with colleagues created a double blinded, randomised placebo controlled trial to test the effects of creatine supplements used alongside an exercise programme. The study focused on patients with coronary artery disease or chronic heart failure over a three-month period.

Creatine is found naturally in our diets, in particular in meat. Creatine is also produced naturally in the human body for use by muscles; skeletal muscles use the vast majority. The remainder is used in the brain and heart. Supplements improve muscle strength, particularly for short-term, high-intensity exercise, and are used by athletes to make their training more effective. It may also help with muscle weakness due to atrophy in a number of clinical conditions.

Previous studies have shown that chronic heart failure patients' skeletal muscle strength can be improved with creatine supplements giving better strength and endurance in cycle ergomotry tests (on a stationary, gym-style bicycle). Cornelissen and Defoor wanted to find out whether creatine would help with cardiorespiratory endurance, muscle strength and endurance during a cardiac rehabilitation programme, too. They reasoned that test results for older patients and cardiac patients may are likely to be lower due primarily to peripheral muscle weakness, and so giving these muscles a creatine boost may lead to more effective rehabilitation fitness results.

As well as measuring aerobic power, strength, endurance and recovery, the researchers looked at patients' quality of life scores and checked they were taking the supplements or placebos according to schedule. The bottom line was that among the 80 patients in the study, the researchers found no significant differences between the two groups.

"Contrary to our hypothesis, the magnitude of increase in muscle strength and/or endurance was not greater in the group with creatine supplementation," said study supervisor, Professor Luc Vanhees.

The rehabilitation programme led to better leg strength, and endurance and recovery and VO2 peak were significantly higher than when patients started. It may be the case that the large effect of the exercise training covered up any smaller effect that was down to the creatine. The researchers also think it is worth considering a therapeutic role for creatine once cardiac patients are already well established with their rehabilitation programme, as it may further boost their performance and let them get past the 'training hump,' although further study is needed to test this hypotheses.


Contact: Jayne Fairley
SAGE Publications UK

Related biology news :

1. Chocolate milk is a natural for post-exercise recovery
2. Muscle mass in elderly boosted by combining resistance exercise and blood flow restriction
3. Vigorous exercise strengthens hip bones in young children
4. Regular aerobic exercise is good for the brain, Pitt team says
5. Exercise therapy for low back pain
6. For osteoporosis patients, exercise pill one step closer to reality
7. Mental health providers should prescribe exercise more often for depression, anxiety
8. The new exercise HIT: do less
9. Exercise counters negative effects of weight regain, researchers find
10. What you eat after exercise matters
11. UB specialized exercise regimen shown to relieve prolonged concussion symptoms
Post Your Comments:
(Date:11/26/2015)... 2015 Research and Markets ( ) ... Sensors - Technology and Patent Infringement Risk Analysis" ... --> Fingerprint sensors using capacitive technology ... fingerprint sensor vendor Idex forecasts an increase of 360% ... devices and of the fingerprint sensor market between 2014 ...
(Date:11/18/2015)... Nov. 18, 2015  As new scientific discoveries deepen ... and other healthcare providers face challenges in better using ... patients. In addition, as more children continue to survive ... adulthood and old age. John M. Maris, ... Hospital of Philadelphia (CHOP) . --> ...
(Date:11/17/2015)... 17, 2015  Vigilant Solutions announces today that Mr. ... of Directors. --> --> ... from the partnership at TPG Capital, one of the ... $140 Billion in revenue.  He founded and led TPG,s ... TPG companies, from 1997 to 2013.  In his first ...
Breaking Biology News(10 mins):
(Date:11/30/2015)... ... November 30, 2015 , ... Imagine Exhibitions and Universal Partnerships ... opening in March 2016 at Melbourne Museum in Melbourne, Australia. Immediately following the ... American tour dates. The Exhibition is based on Universal Pictures’ Jurassic World, one ...
(Date:11/30/2015)... DIEGO , Nov. 30, 2015  HUYA Bioscience ... China,s pharmaceutical innovations, today announced it ... Drug Development Fund (KDDF) to foster collaboration between KDDF ... development and commercialization of healthcare products for the global ... as an important source of new innovative preclinical and ...
(Date:11/30/2015)... -- Northwest Biotherapeutics (NASDAQ: NWBO ) ("NW Bio"), a ... solid tumor cancers, announced today that the Board is ... Company welcomes Neil Woodford,s call for an ... report on NW Bio.  The Company,s Board is under ... stated, "We agree with Mr. Woodford that, at NW ...
(Date:11/27/2015)... CHESTERFIELD, United Kingdom , Nov. 27, 2015 /PRNewswire/--  ... specialty biopharmaceutical company, announced today that it has closed ... systems (CMDS) business to Guerbet (GBT- NYSE Euronext) in ... CMDS operations encompassed four manufacturing facilities and a total ... nearly 75 in the St. Louis ...
Breaking Biology Technology: