Navigation Links
Exercise targets cellular powerhouses to improve heart function
Date:2/12/2014

Whether lifting weights in a gym or just walking around the block, exercise has many benefits, such as helping people lose weight and build stronger muscles. Some studies suggest that it may reduce the risk of developing cancer and other diseases. Researchers now report in ACS' Journal of Proteome Research that moderate, long-term physical activity appears to improve cardiovascular health in mice by targeting the heart cells' powerhouses the mitochondria.

Eduard Sabid, head of the Proteomics Unit at the Centre for Genomic Regulation, in Barcelona, Spain, Francisco Amado and colleagues explain that despite the well-documented benefits of exercise, the exact way that it helps the heart is not well understood. Sure, it helps strengthen the heart muscle so it can pump more blood throughout the body more efficiently. And people who get off the couch and exercise regularly have a reduced risk of developing heart problems and cardiovascular disease. One estimate even claims that 250,000 deaths every year in the U.S. are at least partially due to a lack of exercise. But how this all happens in the body at the molecular level has perplexed researchers until now.

The team found that laboratory mice (stand-ins for humans) that exercised for 54 weeks on a treadmill-running regimen had higher levels of certain proteins in the mitochondria of their heart cells than did mice that did not exercise. Mitochondria produce energy for the body's cells. In particular, they identified two proteins, kinases called RAF and p38, which "seem to trigger the beneficial cardiovascular effects of lifelong exercise training," they say.


'/>"/>

Contact: Gloria Lligadas
gloria.lligadas@crg.eu
34-933-160-153
Center for Genomic Regulation
Source:Eurekalert

Page: 1

Related biology news :

1. Study: Exercise can lead to female orgasm, sexual pleasure
2. Study: Men who do load-bearing exercise in early 20s may be shielded from osteoporosis
3. Dartmouth researchers are learning how exercise affects the brain
4. Dont feel like exercise? Scientists find compound that may help you work out harder
5. Resveratrol may be a natural exercise performance enhancer: U of A medical research
6. Exercise is key in the fight against Alzheimers disease
7. UIC study examines exercise and weight loss for older adults with osteoarthritis
8. 30 minutes of daily exercise does the trick
9. UMD study shows exercise may protect against future emotional stress
10. MARC travel awards announced for the 2012 APS Integrative Biology of Exercise meeting
11. American Physiological Societys latest conference focuses on integrative biology of exercise
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/16/2017)... May 16, 2017  Veratad Technologies, LLC ( www.veratad.com ... age and identity verification solutions, announced today they will ... 2017, May 15 thru May 17, 2017, in ... International Trade Center. Identity impacts the ... in today,s quickly evolving digital world, defining identity is ...
(Date:4/24/2017)... Janice Kephart , former 9/11 ... Partners, LLP (IdSP) , today issues the following ... March 6, 2017 Executive Order: Protecting the ... be instilled with greater confidence, enabling the reactivation ... applications are suspended by until at least July ...
(Date:4/17/2017)... , April 17, 2017 NXT-ID, Inc. ... company, announces the filing of its 2016 Annual Report on Form ... Exchange Commission. ... Form 10-K is available in the Investor Relations section of the ... on the SEC,s website at http://www.sec.gov . 2016 ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... 2017 , ... They call it the “hairy ball.” It’s ... of a system of linkages and connections so complex and dense that “it ... science at Worcester Polytechnic Institute (WPI) and director of the university’s bioinformatics and ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... States multicenter, prospective clinical study that demonstrates the accuracy of the FebriDx® ... identifying clinically significant acute bacterial and viral respiratory tract infections by testing ...
(Date:10/12/2017)... , ... October 12, 2017 ... ... has launched Rosalind™, the first-ever genomics analysis platform specifically designed for life ... Named in honor of pioneering researcher Rosalind Franklin, who made a major ...
(Date:10/11/2017)... , ... October 11, 2017 , ... Personal eye wash is a basic first aid ... at a time. So which eye do you rinse first if a dangerous substance enters ... Plum Duo Eye Wash with its unique dual eye piece. , “Whether its dirt ...
Breaking Biology Technology: