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Exercise for stroke patients' brains
Date:6/11/2013

A new study finds that stroke patients' brains show strong cortical motor activity when observing others performing physical tasks a finding that offers new insight into stroke rehabilitation.

Using functional magnetic resonance imaging (fMRI), a team of researchers from USC monitored the brains of 24 individuals 12 who had suffered strokes and 12 age-matched people who had not as they watched others performing actions made using the arm and hand that would be difficult for a person who can no longer use their arm due to stroke actions like lifting a pencil or flipping a card.

The researchers found that while the typical brain responded to the visual stimulus with activity in cortical motor regions that are generally activated when we watch others perform actions, in the stroke-affected brain, activity was strongest in these regions of the damaged hemisphere, and strongest when stroke patients viewed actions they would have the most difficulty performing.

Activating regions near the damaged portion of the brain is like exercising it, building strength that can help it recover to a degree.

"Watching others perform physical tasks leads to activations in motor areas of the damaged hemisphere of the brain after stroke, which is exactly what we're trying to do in therapy," said Kathleen Garrison, lead author of a paper on the research. "If we can help drive plasticity in these brain regions, we may be able to help individuals with stroke recover more of the ability to move their arm and hand."

Garrison, who completed this research while studying at USC and is currently a post-doctoral researcher at the Yale University School of Medicine, worked with Lisa Aziz-Zadeh of the USC Brain and Creativity Institute and the Division of Occupational Science and Occupational Therapy; Carolee Winstein, director of the Motor Behavior and Neurorehabilitation Laboratory in the Division of Biokinesiology and Physical Therapy at USC; a
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Contact: Robert Perkins
perkinsr@usc.edu
213-740-9226
University of Southern California
Source:Eurekalert

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