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ExcellGene SA first company to offer contract manufacturing in 250 Liter OrbShake bioreactor
Date:5/20/2009

- Cooperations with Sartorius Stedim Biotech (SSB) and Adolf Kühner AG
- Prototype of orbital shake bioreactor presented at ACHEMA 2009

Monthey, 19. Mai 2009 / b3c newswire / – ExcellGene SA, a leading provider of contract manufacturing to the biopharmaceutical industry, expands its product offering with the introduction of the 250 Liter OrbShake bioreactor. OrbShake bioreactors rely on orbital shaking principles for mixing compared to stirring or wave-like movements in order to achieve a superior oxygen transfer while minimizing shear forces. The OrbShake bioreactors were developed jointly with Sartorius Stedim Biotech (SSB) and Adolf Kühner AG.

ExcellGene SA will be the first company to offer to its clients production of recombinant proteins at the 50L to 200L scale in OrbShake bioreactors. The combination of orbital shaking with disposable technology will allow the fast and highly economical production of gram quantities of protein for pre-clinical testing and Phase I studies under cGMP and non-cGMP conditions.
 
Prof. Dr. Wurm, founder and CSO of ExcellGene SA comments: “ExcellGene has always been at the forefront of innovation – be it our TubeSpin system for high-throughput process development or our transient gene expression technology platform with yields well above 1 gram per liter. With the introduction of our latest innovation, the 250L OrbShake bioreactor, we will be able to offer to our clients gram to 10s of gram quantities of recombinant proteins at unparalleled speed, quality and low cost.  Orbital shaking allows for high yields and short timelines as it offers optimal growth and production conditions for mammalian cell lines. In combination with the cost, quality and time advantage of disposable technology, our platform provides a highly valuable alternative to conventional, stirred-tank bioreactors.”

About ExcellGene SA
Founded barely 7 years ago, ExcellGene SA, privately owned, is already a leading process science company in the pharmaceutical biotechnology sector. ExcellGene discovers and develops innovative technologies for the production of recombinant proteins from mammalian cells in bioreactors. As a service company, ExcellGene generates entire upstream cell culture processes for its customers, from DNA to scalable manufacturing under cGMP. Additionally, the company provides protein production services, based both on stable cell lines and on large-scale transient gene expression. The company is located in Monthey, Switzerland.  For additional information, please visit http://www.excellgene.com or contact us directly at bd@excellgene.com.

About Kuehner AGKühner AG, Birsfelden (Basel), Switzerland has been designing and manufacturing shakers since 1949. Known worldwide for our quality and reliability, our range spans from the small table top shakers / incubator shakers to the very large 6-tray pilot shaker. We sell them through a worldwide network of dedicated distributors. Cooperation with well-known universities / polytechnical schools and our own application-driven development department is the key to our innovation. We organize advanced training, conferences and individual consultancy for our customers in the application of shaken bioreactors thus complementing the Kühner range of services. For additional information about the company, please visit http://www.kuhner.com.

About Sartorius-Stedim Biotech
Sartorius Stedim Biotech is a leading provider of cutting-edge equipment and services for the development, quality assurance and production processes of the biopharmaceutical industry.  Its integrated solutions covering fermentation, filtration, purification, fluid management and lab technologies are supporting the biopharmaceutical industry around the world to develop and produce drugs safely, timely and economically.  For next generation processes, Sartorius Stedim Biotech focuses on single-use technologies and value-added services to meet the rapidly changing technology requirements of the industry it serves.  Strongly rooted in the scientific community and closely allied with customers and technology partners, the company is dedicated to its philosophy of “turning science into solutions” on a daily basis. For additional information, please visit http:// www.sartorius.com.com.

Contact
Markus Hildinger
Chief Business Officer
ExcellGene SA
Route de l’ile-au-bois 1A
CH-1870 Monthey, Valais
Phone: +41 79 772 9995
contact@excellgene.com
www.excellgene.com


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