Navigation Links
Evolutionary kings of the hill use good, bad and ugly mutations to speed ahead of competition
Date:6/30/2011

EAST LANSING, Mich. Evolutionary adaptation is often compared to climbing a hill, and organisms making the right combination of multiple mutations both good and bad can become the king of the mountain.

A new study published in the Proceedings of the Royal Society B by BEACON researchers at Michigan State University suggests that the combined effect of multiple mutations working together can speed up this process. Through computer simulations, researchers at BEACON, a National Science Foundation-funded Science and Technology Center at MSU, were able to watch evolution play out and see how populations use these combinations to evolve from one adaptive state to another.

Traditional molecular biology approaches allow researchers to look only at so many genes at once. In comparison, computer simulations can process a bigger set of mutations and analyze them consecutively, offering a much more complex and more realistic view of how evolution works in real life, said Bjorn Ostman, postdoctoral researcher at BEACON.

"In reality, many mutations that affect different traits interact with each other, and a single mutation also can affect multiple traits," he said. "Multiple mutations may actually cooperate to give the organism a bigger boost in fitness than the individual mutations would on their own."

Recent evolutionary experiments look at a relatively short period of adaptation where only beneficial mutations occurred. Taking a different approach, Ostman and the team did not focus solely on beneficial mutations. Bad mutations as well as the ones needed to overcome them can actually interact with beneficial mutations to enable organisms to achieve high fitness being able to survive and reproduce at a high rate and cross valleys of low fitness, sometimes even accelerating evolution.

"We were able to examine multiple peaks and valleys rather than focus solely on how a population climbs a single peak," Ostman said. "These fitness landscapes simply could not be traversed with mutations that did not interact."


'/>"/>

Contact: Layne Cameron
layne.cameron@ur.msu.edu
517-353-8819
Michigan State University
Source:Eurekalert

Related biology news :

1. Illuminating biology: An evolutionary perspective
2. Revealing the evolutionary history of threatened sea turtles
3. Details of evolutionary transition from fish to land animals revealed
4. Genetic based human diseases are an ancient evolutionary legacy
5. Flies may reveal evolutionary step to live birth
6. Evolution in action: Our antibodies take evolutionary leaps to fight microbes
7. Scientists uncover evolutionary keys to common birth disorders
8. Evolutionary process more detailed than previously believed, study shows
9. Dinosaur fossils fit perfectly into the evolutionary tree of life
10. Singapore-US scientists first to develop revolutionary microchip that uses 30 times less energy
11. Pubic hair provides evolutionary home for gorilla lice
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2016)... Dec. 15, 2016 Advancements in ... health wellness and wellbeing (HWW), and security ... three new passenger vehicles begin to feature ... recognition, heart beat monitoring, brain wave monitoring, ... monitoring, and pulse detection. These will be ...
(Date:12/12/2016)... , Dec. 12, 2016  Researchers at ... possibilities for graphene by combining the material with ... highly sensitive pressure detector able to sense pulse, ... a small spider.  The research ... can be read here:  http://science.sciencemag.org/content/354/6317/1257 ...
(Date:12/7/2016)... India , December 7, 2016 According to a ... Machine Learning), Software Tool (Facial Expression, Voice Recognition), Service, Application Area, End User, ... is estimated to grow from USD 6.72 Billion in 2016 to USD 36.07 ... Continue Reading ... ...
Breaking Biology News(10 mins):
(Date:1/19/2017)... 18, 2017 BD (Becton, Dickinson and Company) (NYSE: ... it will host a live webcast of its Annual Meeting of ... The webcast can be accessed from the BD corporate ... Tuesday, January 31, 2017. ... About BD BD is a global medical technology ...
(Date:1/18/2017)... Jan. 18, 2017   Boston Biomedical , an ... to target cancer stemness pathways, will feature data from ... at the 2017 ASCO Gastrointestinal Cancers Symposium, held from ... Napabucasin is an orally-administered investigational agent ... i Cancer stem cells (CSCs) possess the property ...
(Date:1/18/2017)... ... January 18, 2017 , ... ... Executives 2017 in its continued commitment to the advancement of the clinical trials ... current issues related to clinical trial planning and management. , As executive ...
(Date:1/18/2017)... Frederick, Maryland (PRWEB) , ... January 18, 2017 ... ... of two new federally funded bio-focused Manufacturing Innovation Institutes (MII). U.S. Secretary of ... Innovation in Manufacturing Biopharmaceuticals (NIIMBL), and the Department of Defense has announced the ...
Breaking Biology Technology: