Navigation Links
Evolutionary kings of the hill use good, bad and ugly mutations to speed ahead of competition
Date:6/30/2011

EAST LANSING, Mich. Evolutionary adaptation is often compared to climbing a hill, and organisms making the right combination of multiple mutations both good and bad can become the king of the mountain.

A new study published in the Proceedings of the Royal Society B by BEACON researchers at Michigan State University suggests that the combined effect of multiple mutations working together can speed up this process. Through computer simulations, researchers at BEACON, a National Science Foundation-funded Science and Technology Center at MSU, were able to watch evolution play out and see how populations use these combinations to evolve from one adaptive state to another.

Traditional molecular biology approaches allow researchers to look only at so many genes at once. In comparison, computer simulations can process a bigger set of mutations and analyze them consecutively, offering a much more complex and more realistic view of how evolution works in real life, said Bjorn Ostman, postdoctoral researcher at BEACON.

"In reality, many mutations that affect different traits interact with each other, and a single mutation also can affect multiple traits," he said. "Multiple mutations may actually cooperate to give the organism a bigger boost in fitness than the individual mutations would on their own."

Recent evolutionary experiments look at a relatively short period of adaptation where only beneficial mutations occurred. Taking a different approach, Ostman and the team did not focus solely on beneficial mutations. Bad mutations as well as the ones needed to overcome them can actually interact with beneficial mutations to enable organisms to achieve high fitness being able to survive and reproduce at a high rate and cross valleys of low fitness, sometimes even accelerating evolution.

"We were able to examine multiple peaks and valleys rather than focus solely on how a population climbs a single peak," Ostman said. "These fitness landscapes simply could not be traversed with mutations that did not interact."


'/>"/>

Contact: Layne Cameron
layne.cameron@ur.msu.edu
517-353-8819
Michigan State University
Source:Eurekalert

Related biology news :

1. Illuminating biology: An evolutionary perspective
2. Revealing the evolutionary history of threatened sea turtles
3. Details of evolutionary transition from fish to land animals revealed
4. Genetic based human diseases are an ancient evolutionary legacy
5. Flies may reveal evolutionary step to live birth
6. Evolution in action: Our antibodies take evolutionary leaps to fight microbes
7. Scientists uncover evolutionary keys to common birth disorders
8. Evolutionary process more detailed than previously believed, study shows
9. Dinosaur fossils fit perfectly into the evolutionary tree of life
10. Singapore-US scientists first to develop revolutionary microchip that uses 30 times less energy
11. Pubic hair provides evolutionary home for gorilla lice
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/26/2016)... , April 27, 2016 ... the  "Global Multi-modal Biometrics Market 2016-2020"  report to ... ) , The analysts forecast the ... CAGR of 15.49% during the period 2016-2020.  ... number of sectors such as the healthcare, BFSI, ...
(Date:4/15/2016)... , April 15, 2016  A new partnership ... more accurate underwriting decisions in a fraction of ... competitively priced and high-value life insurance policies to ... With Force Diagnostics, rapid testing (A1C, ... data readings (blood pressure, weight, pulse, BMI, and ...
(Date:4/14/2016)... 14, 2016 BioCatch ™, ... today announced the appointment of Eyal Goldwerger ... Goldwerger,s leadership appointment comes at a time ... the deployment of its platform at several of the ... which discerns unique cognitive and physiological factors, is a ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... June 23, 2016 , ... In a new case report ... detail how a patient who developed lymphedema after being treated for breast cancer benefitted ... change the paradigm for dealing with this debilitating, frequent side effect of cancer treatment. ...
(Date:6/23/2016)... , June 23, 2016 ... Hematology Review, 2016;12(1):22-8 http://doi.org/10.17925/OHR.2016.12.01.22 ... , the peer-reviewed journal from touchONCOLOGY, Andrew ... escalating cost of cancer care is placing an ... result of expensive biologic therapies. With the patents ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... quality, regulatory and technical consulting, provides a free webinar on Performing ... July 13, 2016 at 12pm CT at no charge. , Incomplete investigations are ...
(Date:6/23/2016)... ReportsnReports.com adds 2016 global ... pharmaceuticals section with historic and forecast data along ... Complete report on the Cell Culture ... companies and supported with 261 tables and figures ... The Global Cell Culture Media Industry ...
Breaking Biology Technology: