Navigation Links
Evolution of the sexes: What a fungus can tell us
Date:1/9/2008

es are able to mate with each other.

Both versions of the gene, sexM and sexP, encode for a single protein called a high mobility group (HMG)-domain protein that leads to sex differentiation through an unknown process. This protein is very similar to one encoded by the human Y chromosome, called SRY, that when turned on leads a developing fetus to exhibit male characteristics. Heitman said this similarity suggests that HMG-domain proteins may mark the evolutionary beginnings of sex determination in both fungi and humans.

Heitman's team proposes that sexM and sexP were once the same gene that went through a mutation process called inversion. The new versions then evolved into two separate sex genes. The same process is most likely responsible for the evolution of the male Y chromosome, Heitman suggests.

Heitman hopes to next identify the sex region in another fungus, Rhizopus oryzae in order to better understand how HMG-domain proteins control sex determination in fungi. Rhizopus' genes can be cultured and chemically altered in a way that Phycomyces' sex genes can not.

"Rhizopus can be used to understand the influences of certain genes in lesser studied fungi much in the way we use mice to understand genetic effects in humans," explained Alexander Idnurm, Ph.D., the primary author on the study and recently appointed assistant professor at the University of Missouri-Kansas City.

Another troubling mystery for Heitman is that certain younger fungal species lack HMG-domain proteins. He proposes that these proteins have been replaced with alternative transcription factors, which are proteins that turn genes on and off.


'/>"/>

Contact: Kelly Malcom
kelly.malcom@duke.edu
919-668-1889
Duke University Medical Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. Evolution is driven by gene regulation
2. Clones on task serve greater good, evolutionary study shows
3. Adaptation to parasites drive African fishes along different evolutionary paths
4. Uncertainty drives the evolution of cooperative breeding in birds
5. Structure of 450 million year old protein reveals evolutions steps
6. Scientists retrace evolution with first atomic structure of an ancient protein
7. Hidden interactions between predators and prey: evolution causes cryptic dynamics in ecology
8. Migrating squid drove evolution of sonar in whales and dolphins, researchers argue
9. Old developmental pathways spawn revolutionary evolutionary changes
10. Systems Biology poised to revolutionize the understanding of cell function and disease
11. Using evolution, UW team creates a template for many new therapeutic agents
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... kidney injury related to the use of hydroxyethyl starch ... molecules, according to a report in Anesthesia & ... Society (IARS). , The "total mass of HES molecules" ... renal proximal tubule cells (PTCs), concludes the laboratory study ... Wrzburg, Austria. Other factorssuch as differences in the ...
(Date:7/11/2014)... addition to the hippocampus, the marginal division of ... memory. What is the impact degree of substance ... and memory function? Yan Yu and his team, ... found, using immunofluorescence staining, that substance P receptor, ... and striatal marginal division of normal rats. Unilateral ...
(Date:7/11/2014)... Evidence exists that cannabinoid receptor type 1 ... Ca2+ influx, and reduce neurotransmitter release. However, ... 1 can increase extracellular Ca2+ influx and ... his team, Tongji Hospital Affiliated to Tongji ... Technology, China used whole cell voltage-clamp and ...
Breaking Biology News(10 mins):In lab studies, hydroxyethyl starch has direct harmful effects on kidney cells 2
... by scientists at The University of Texas Medical School ... vascular smooth-muscle cells in people who suffer from hereditary ... warning in the prime of their lives. Thoracic ... dissections, is the 15th leading cause of death in ...
... appealed for more information on the worlds biodiversity to ... to understand the impact of climate change on the ... by the Biotechnology and Biological Sciences Research Council (BBSRC), ... and computer scientists at the University of Cardiff, has ...
... Researchers at Childrens Hospital of Pittsburgh of UPMC are participating ... effectiveness of oral insulin in preventing or delaying the onset ... disease. The researchers want to determine if one insulin ... type 1 diabetes in relatives of people who are found ...
Cached Biology News:Life-threatening gene defect located by UT-Houston researchers 2Life-threatening gene defect located by UT-Houston researchers 3Life-threatening gene defect located by UT-Houston researchers 4How global is the Global Biodiversity Information Facility? 2Children's Hospital studying drug with the potential to prevent/delay onset of type 1 diabetes 2
(Date:7/10/2014)... 10, 2014 /PRNewswire-iReach/ -- Tute Genomics, the ... announced an agreement with Lineagen, Inc., to ... NextStep Dx PLUS.  Lineagen, focused on ... disorders, currently offers FirstStep Dx PLUS, ... used by healthcare providers as a first-line ...
(Date:7/10/2014)... may help in the fight against terrorism with the ... of explosives with the use of light and special ... and Actuators B: Chemical , the researchers describe a ... concentrations as low as 6.3 ppm (parts per million). ... minutes. , "Traditionally explosives detection has involved looking for ...
(Date:7/10/2014)... fractional quantum Hall effect in bilayer graphene and shown ... by an electric field. , The fractional quantum ... thin sheets are exposed to large magnetic fields, is ... individual electrons behave as a single system. However, while ... many details of this collective behavior remain not well ...
(Date:7/10/2014)... University of Illinois at Urbana-Champaign provides new insights ... spin and heat at the nanoscale, and addresses ... data storage and information processing. , "Electrons ... In a typical charge current, electrons, spin-angular-momentum is ... David Cahill, a professor of materials science and ...
Breaking Biology Technology:Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 3Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 4Detecting trace amounts of explosives with light 2Columbia researchers observe tunable quantum behavior in bilayer graphene 2Columbia researchers observe tunable quantum behavior in bilayer graphene 3University of Illinois study advances limits for ultrafast nano-devices 2
... created equal. Information lifecycle management, a fresh concept in ... and placed them into tiers associated with different costs ... from customer orders to pictures of your last fishing ... elses data. Each piece of data doesnt have the ...
... transfer and commercialization efforts are on the rise in ... of Wisconsin to intensify its efforts at technology transfer, ... Center for Advanced Technology & Innovation (CATI) ... industry technology transfer in the Madison area. We Energies ...
... Science faculty at the University of Wisconsin-Eau Claire ... opportunities to work on research relating to materials ... university to assist local industries. , ,UW-Eau Claires ... facilitate collaboration among science faculty across disciplines, promote ...
Cached Biology Technology:Save money while your data grows 2Madison Development Corp. and CATI form tech transfer partnership 2UW-Eau Claire creates Materials Science Center 2UW-Eau Claire creates Materials Science Center 3
...
For mRNA Differential Display with three one-base anchored oligo-dT primers and rationally designed arbitrary 13mers. These kits feature the latest generation of isotopic mRNA Differential Display t...
NATIVE, ENZYME PORCINE TRYPSIN...
G-Protein Coupled Receptor Assay, For 500 assays. SPA. Category: Drug Screening & Cellular Assays, Assays ....
Biology Products: