Navigation Links
Evolution of staph 'superbug' traced between humans and food animals
Date:2/21/2012

FLAGSTAFF, Ariz. -- A strain of the potentially deadly antibiotic-resistant bacterium known as MRSA has jumped from food animals to humans, according to a new study involving two Northern Arizona University researchers.

Paul Keim, Regents professor and director of NAUs Center for Microbial Genetics and Genomics, and Lance Price, NAU faculty member and director of the Center for Food Microbiology and Environmental Health at the Translational Genomics Research Institute, collaborated with scientists at 20 institutions around the world on the study published today in the online journal mBio.

The TGen-led research utilized whole genome sequencing to study 89 genomes from humans and animals including turkeys, chickens and pigs with samples from 19 countries on four continents.

The research focused on methicillin-resistant Staphylococcus aureus CC398, also known as pig MRSA or livestock-associated MRSA because it most often infects people with direct exposure to swine or other food animals. It is likely that MRSA CC398 started as an antibiotic-susceptible strain in humans before it jumped to food animals.

After transferring to food animals, MRSA CC398 became resistant to two important antibiotics, tetracycline and methicillin, which are used for treating staph infections. The resistance likely is a result of the routine antibiotic use that characterizes modern food-animal production. The animals commonly are given antibiotics to prevent infection and promote growth.

Keim, who also serves as director of TGens Pathogenic Genomics Division, said the study describes evolution in action. "The most powerful force in evolution is selection. And in this case, humans have supplied a strong force through the excessive use of antibiotic drugs in farm animal production. It is that inappropriate use of antibiotics that is now coming back to haunt us.

Price, the studys lead author, said the research was like watching the birth of a superbugit is simultaneously fascinating and disconcerting. He said that while this strain of MRSA was discovered less than a decade ago it appears to be spreading very quickly.

Our findings underscore the potential public health risks of widespread antibiotic use in food animal production, Price said. Staph thrives in crowded and unsanitary conditions. Add antibiotics to that environment and youre going to create a public health problem.


'/>"/>

Contact: Cynthia Brown
cindy.brown@nau.edu
928-523-0611
Northern Arizona University
Source:Eurekalert

Related biology news :

1. Worm genome offers clues to evolution of parasitism
2. Advance offers revolution in food safety testing
3. Mass extinctions and the evolution of dinosaurs
4. Egalitarian revolution in the Pleistocene?
5. Reproducing early and often is the key to rapid evolution in plants
6. Illuminating biology: An evolutionary perspective
7. Biologists, educators recognize excellence in evolution education
8. Revealing the evolutionary history of threatened sea turtles
9. Details of evolutionary transition from fish to land animals revealed
10. Genetic based human diseases are an ancient evolutionary legacy
11. Wake Forest plays integral role in effort to revolutionize vehicle safety
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/20/2017)... , July 20, 2017 Delta (NYSE: DAL ) ... any Delta aircraft at Reagan Washington National Airport (DCA). ... Delta launches biometrics to board ... Delta,s biometric boarding ... Club is now integrated into the boarding process to allow eligible ...
(Date:6/14/2017)... IBM ) is introducing several innovative partner startups at VivaTech ... startups and global businesses, taking place in Paris ... will showcase the solutions they have built with IBM Watson ... France is one of the most dynamic ... in the number of startups created between 2012 and 2015*, ...
(Date:5/16/2017)... 16, 2017   Bridge Patient Portal , ... MD EMR Systems , an electronic medical ... GE, have established a partnership to build an ... the GE Centricity™ products, including Centricity Practice Solution ... These new integrations will allow healthcare delivery ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... DuPont Pioneer and ... they have entered into a multiyear collaboration to identify and characterize novel CRISPR-Cas ... tools for gene editing across all applications. , Under the terms of the ...
(Date:10/11/2017)... N.C. (PRWEB) , ... October 11, 2017 , ... ... ARCS® Foundation President Andi Purple announced Dr. Suneel I. Sheikh, the co-founder, ... ( ASTER Labs ), Inc. has been selected for membership in ARCS ...
(Date:10/11/2017)... BioMarketing, a leading provider of patient support solutions, has announced ... network, which will launch this week. The VMS CNEs will ... to enhance the patient care experience by delivering peer-to-peer education ... professionals to help women who have been diagnosed and are ... ...
(Date:10/10/2017)... DIEGO, CALIF. (PRWEB) , ... October 10, 2017 , ... ... as part of its corporate rebranding initiative announced today. The bold new look ... its reach, as the company moves into a significant growth period. , It will ...
Breaking Biology Technology: