Navigation Links
Evolution is as complicated as 1-2-3
Date:9/19/2012

EAST LANSING, Mich. A team of researchers at Michigan State University has documented the step-by-step process in which organisms evolve new functions.

The results, published in the current issue of Nature, are revealed through an in-depth, genomics-based analysis that decodes how E. coli bacteria figured out how to supplement a traditional diet of glucose with an extra course of citrate.

"It's pretty nifty to see a new biological function evolve," said Zachary Blount, postdoctoral researcher in MSU's BEACON Center for the Study of Evolution in Action. "The first citrate-eaters were just barely able to grow on the citrate, but they got much better over time. We wanted to understand the changes that allowed the bacteria to evolve this new ability. We were lucky to have a system that allowed us to do so."

Normal E. coli can't digest citrate when oxygen is present. In fact, it's a distinct hallmark of E. coli. They can't eat citrate because E. coli don't express the right protein to absorb citrate molecules.

To decipher the responsible mutations, Blount worked with Richard Lenski, MSU Hannah Distinguished Professor of Microbiology and Molecular Genetics. Lenski's long-term experiment, cultivating cultures of fast-growing E. coli, was launched in 1988 and has allowed him and his teammates to study more than more than 56,000 generations of bacterial evolution.

The experiment demonstrates natural selection at work. And because samples are frozen and available for later study, when something new emerges scientists can go back to earlier generations to look for the steps that happened along the way.

"We first saw the citrate-using bacteria around 33,000 generations," Lenski explained. "But Zack was able to show that some of the important mutations had already occurred before then by replaying evolution from different intermediate stages. He showed you could re-evolve th
'/>"/>

Contact: Layne Cameron
layne.cameron@cabs.msu.edu
517-353-8819
Michigan State University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Leading evolutionary scientist to discuss how genome of bacteria has evolved
2. An evolutionary surprise
3. Ancient Egyptian cotton unveils secrets of domesticated crop evolution
4. Did climate change shape human evolution?
5. A University of Tennessee professors hypothesis may be game changer for evolutionary theory
6. Analysis of stickleback genome sequence catches evolution in action
7. Study shows unified process of evolution in bacteria and sexual eukaryotes
8. Rapid method of assembling new gene-editing tool could revolutionize genetic research
9. Whats in a surname? New study explores what the evolution of names reveals about China
10. Scientists trace evolutionary history of what mammals eat
11. Not by DNA alone: How the epigenetics revolution is fostering new medicines
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Evolution is as complicated as 1-2-3
(Date:10/15/2014)... -- NXT-ID, Inc. (NASDAQ: NXTD and NXTDW) ("NXT-ID" ... mobile commerce market releases photos and video of the recent opening ... 13 th . Gino Pereira , CEO ... investor Mr. Chad A. Verdi rang the bell.  ... investors and employees "for their work and dedication in bringing the ...
(Date:10/14/2014)... Cancer Research shows SIRT6—a protein known to ... the development of skin cancers by turning on an ... skin cells. , Previously considered protective, SIRT6 is part ... help regulate genomic stability and prevent some of the ... damage, which can lead to cancer. This study, in ...
(Date:10/14/2014)... a new kind of stem cell that can become either ... vessels, according to a study published today in the journal ... cell type contradicts current theory on how organs arise from ... origins of, and future treatment for, liver cancer., Thanks to ... complex being made up of more than 200 cell types. ...
Breaking Biology News(10 mins):Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 3Two-faced gene: SIRT6 prevents some cancers but promotes sun-induced skin cancer 2Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg 2Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg 3
... around biological data from electronic tags, ear bone microchemistry and ... one side of the Atlantic influences the other side. ... declined precipitously since 1950, according to the study published today ... The model estimates the number of Atlantic bluefin tuna remaining ...
... peer-reviewed scientific studies of the effects on wildlife of ... adequately assess their impact, especially in the desert Southwest, ... U.S. Geological Survey and published in the journal ... of the paper, USGS scientist Jeffrey Lovich and Maryville ...
... oil spill in the Gulf of Mexico, the U.S. ... Engineering and National Research Council to convene a committee ... disaster and identify measures for preventing similar harm in ... IMPROVING OFFSHORE DRILLING SAFETY, the committee,s final report, analyzes ...
Cached Biology News:New study provides comprehensive view of the status of Atlantic bluefin tuna 2New study provides comprehensive view of the status of Atlantic bluefin tuna 3Literature review on solar energy and wildlife impacts research 2
(Date:10/22/2014)... - iCo Therapeutics ("iCo" or "the Company") (TSX-V: ICO) ... Oral Amphotericin B program.  The company recently announced ... work involving samples from HIV/AIDS patients exposed to ... clinical studies and regulatory filings to move forward ... approximately $700,000 of funding and technological advice from ...
(Date:10/22/2014)... and HONG KONG , Oct. 22, ... therapeutics enterprise, announced today that rare disease expert ... vice president, research. Dr. McKew brings more than two ... positions at the National Institutes of Health, Wyeth Research ... Wyeth). Dr. McKew will lead aTyr,s efforts to expand and ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 Convey ... that a team from Iowa State University won first ... contest. Using a Convey HC-2ex, the team’s solution achieved ... times faster than the second place finisher. , Experts ... embarked upon the month long challenge, using a variety ...
(Date:10/20/2014)... , October 20, 2014 , ... (GI) disorders and the delivery of care has revealed ... and worrying inequalities in the provision of healthcare services ... was commissioned by United European Gastroenterology (UEG), have been ... and public awareness of the burden of GI disorders ...
Breaking Biology Technology:iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 2iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 3aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 2aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 3Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 2Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 2Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 4Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 5
... Portfolio of Regenerative TreatmentsNEW YORK, May 11, NeoStem, ... pioneering the pre-disease collection, processing and long-term storage of ... it has signed an exclusive royalty-bearing license agreement for ... rapidly grows a patient,s own adult stem cells to ...
... /PRNewswire-FirstCall/ - OncoGenex Pharmaceuticals, Inc. (NASDAQ: ... from a randomized Phase 2 trial evaluating OGX-011 ... first-line chemotherapy in patients with metastatic castration-resistant prostate ... at the American Society of Clinical Oncology (ASCO) ...
... European alliances and gears up for business at world,s major chemical ... ... (Vocus) May 11, 2009 -- The Northern Ireland based manufacturer of ... is boosting its European distribution network ahead of its attendance ...
Cached Biology Technology:NeoStem Obtains Exclusive License to Innovative Stem Cell Procedure Treating Musculoskeletal Diseases 2NeoStem Obtains Exclusive License to Innovative Stem Cell Procedure Treating Musculoskeletal Diseases 3NeoStem Obtains Exclusive License to Innovative Stem Cell Procedure Treating Musculoskeletal Diseases 4OncoGenex Pharmaceuticals' Clinical Programs to be Featured in Oral Presentations at the American Society of Clinical Oncology Annual Meeting 2OncoGenex Pharmaceuticals' Clinical Programs to be Featured in Oral Presentations at the American Society of Clinical Oncology Annual Meeting 3Pharmaceutical Packaging Equipment Manufacturer Boosts European Distribution 2Pharmaceutical Packaging Equipment Manufacturer Boosts European Distribution 3
... GenePix Professional 4200A can be upgraded to ... automatically loads, scans, analyzes, and saves results ... you by email when the batch is ... even for warped slides. GenePix Pro gives ...
... the value of your microarray data using ... you need from consultation to extensive data ... methods. Utilize our expertise in combination with ... your own microarray experiments., ,Normalization and basic ...
... Maximize the value of your ... We offer the support you need ... using the most up to date ... with the Gene Expression Profiling Service ...
... This CLS number is a ... easily match Cornings product number. ... please order under the old ... customer service for assistance. ...
Biology Products: