Navigation Links
Evidence now suggests eating soy foods in puberty protects against breast cancer
Date:4/9/2008

pubertal exposure to genistein are very consistent in showing a reduction in mammary cancer risk, she says. Exposure to soy in fetal development or in adult life does not have the same protective effect.

Further examination of experimental versus control rats demonstrated that use of genistein in puberty cut the number of so-called terminal end buds in the breast. These are the structures that lead to growth of the mammary epithelium, which are the cells lining milk ducts, etc., and it is in these epithelial cells that breast cancer originates. But Hilakivi-Clarke says it is not clear if a mere reduction in the number of these structures could reduce cancer risk, or why.

Other studies suggest that genistein controls expression of genes in terminal end buds that regulate cell growth, repair and death. For example, the chemical could be controlling the ability of stem cells, found on these buds, to reproduce themselves or to differentiate into more specialized cells. There is evidence that suggests that the more stem cells there are on these structures, the greater the risk of breast cancer development, she says. This evidence supports the theory that breast cancer arises from stem cells that have lost growth control.

Other associated research has found that the genes that genistein appears to activate in developing mammary glands are well known --- BRCA1, p53, and PTEN tumor suppressors, Hilakivi-Clarke says. These genes repair genetic damage and control cell survival and death, and they may also help control stem cell reproduction, she says, and genistein apparently up-regulates these genes, boosting production of their beneficial proteins.

What is perhaps most intriguing, she says, is that the same process that protects the breast from excess growth during pregnancy seems to be at work during puberty. In pregnancy, BRCA1 is also up-regulated, perhaps in order to control the fate of stem cells, allowing them to make more cells for
'/>"/>

Contact: Karen Mallet
km463@gmail.com
414-312-7085
Georgetown University Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. A private bandwidth for communication in bats: Evidence from insular horseshoe bats
2. Comet probes reveal evidence of origin of life, scientists claim
3. Evidence of a relationship between swimming babies and infections
4. Researchers find evidence linking stress caused by the Sept. 11 disaster with low birth weights
5. Fossil record supports evidence of impending mass extinction
6. New evidence for female control in reproduction
7. RAND study finds evidence disease management programs
8. CWRU School of Medicine has evidence vaccine against malaria will reduce disease
9. There is powerful evidence of evolution in human DNA
10. Scientific evidence supporting evolution continues to grow
11. No convincing evidence for decline in tropical forests
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/29/2014)... by the international Cancer Genomics of the Kidney ... between kidney cancer and exposure to aristolochic acid, ... published in Nature Communications , have important ... more than 140,000 people every year, and in ... CAGEKID, part of the International Cancer Genome Consortium ...
(Date:10/28/2014)... have published a paper in the Proceedings of ... details about key transitions in the evolution of plant ... mosses, ferns, trees and flowers growing deep in steamy ... the ornamental plants adorning our homes, all plant life ... "Our study generated DNA sequences from a vast number ...
(Date:10/28/2014)... be building a hybrid micro-grid which will integrate ... in the region, the hybrid micro-grid will test ... diesel, storage and power-to-gas technologies, and ensure these ... built under the new Renewable Energy Integration Demonstrator- ... located offshore at Semakau Landfill and is expected ...
Breaking Biology News(10 mins):Kidney cancer in Central Europe 2New study uses DNA sequences to look back in time at key events in plant evolution 2New study uses DNA sequences to look back in time at key events in plant evolution 3NTU to build region's first renewable energy integration demonstration micro-grid 2NTU to build region's first renewable energy integration demonstration micro-grid 3
... Mary Lee Dequeant, Ph.D., a Predoctoral Researcher at the ... Stowers Institute Investigator and an investigator with the Howard ... respectively, on a paper that identifies a network of ... of spine formation in the embryo. , ...
... identified the molecular signature of these epidermal neural crest ... conflicting scientific opinions by showing that these cells are ... Their work provides a valuable resource for future mouse ... the research from Dr. Maya Sieber-Blum's laboratory, co-authored by ...
... University researchers have identified a unique mechanism of action ... the treatment of multiple sclerosis. , The researchers report ... drug that was already known to affect the functioning ... white blood cells from the lymph nodes into the ...
Cached Biology News:Stem cells found in adult hair follicles may provide alternative to embryonic stem cells 2Novel mechanism of action of new drug for MS identified 2
(Date:10/27/2014)... 2014 Kalorama Information says that PCR is ... the United States and is ... researcher said the FDA,s Emergency Use Authorization (EUA) to authorize ... the detection of the Ebola virus was an indication ... assess the IVD industry and its biennial survey on ...
(Date:10/27/2014)... The report “Smart Highway Market ... Communication, Monitoring), and by Display (Variable Message Signs, ... the global market into various sub-segments with in-depth ... the drivers and restraints for this market with ... 75 market tables and 37 figures spread through ...
(Date:10/26/2014)... The report "Data Center Networking ... Equipment, WAN Optimization Appliances]: Global Advancements, Worldwide Forecasts ... center networking market into various segments with an ... also identifies the factors driving this market, various ... with the future roadmaps. , Browse 106 market ...
(Date:10/25/2014)... (PRWEB) October 23, 2014 BioProcess ... winners for the 2014 BioProcess International Awards. The ... social corporate responsibility and technology applications that will ... treatments to a global patient base. , Winners ... peers during a very entertaining and exciting awards ...
Breaking Biology Technology:Kalorama: PCR The Go-to Test in Ebola Fight 2Kalorama: PCR The Go-to Test in Ebola Fight 3Smart Highway Market by Technology, and Display Expected to Reach $27.992.0 Million by 2019- New Report by MarketsandMarkets 2Smart Highway Market by Technology, and Display Expected to Reach $27.992.0 Million by 2019- New Report by MarketsandMarkets 3Smart Highway Market by Technology, and Display Expected to Reach $27.992.0 Million by 2019- New Report by MarketsandMarkets 4Data Center Networking Market by Ethernet Switches, SAN & Routers Worth $21.85 Billion by 2018 - New Report by MarketsandMarkets 2Data Center Networking Market by Ethernet Switches, SAN & Routers Worth $21.85 Billion by 2018 - New Report by MarketsandMarkets 3Data Center Networking Market by Ethernet Switches, SAN & Routers Worth $21.85 Billion by 2018 - New Report by MarketsandMarkets 4BioProcess International Announces Winners of the 2014 BioProcess International Awards 2BioProcess International Announces Winners of the 2014 BioProcess International Awards 3BioProcess International Announces Winners of the 2014 BioProcess International Awards 4BioProcess International Announces Winners of the 2014 BioProcess International Awards 5
... BEIJING, Aug. 20 /PRNewswire-Asia-FirstCall/ -- China Medical ... leading China-based medical device,company that develops, manufactures and markets ... its unaudited financial results,for the fourth fiscal quarter ("4Q ... the first fiscal quarter ("1Q FY2009") ended June 30, ...
... , SEATTLE, Aug. 19 Cell Therapeutics, Inc. ... into an agreement to sell $30 million of shares of its Series ... in a registered offering to a single institutional investor. Each share ... holder, at any time during its existence, into approximately 628 shares of ...
... , , COLUMBIA, Md., Aug. 19 Martek Biosciences ... the results of its third quarter of fiscal 2009 on September 2, ... at 4:45 p.m. ET Martek will conduct a conference call to discuss ... call live via webcast by visiting Martek,s web site at ...
Cached Biology Technology:China Medical Technologies to Announce Unaudited Financial Results for the Fourth Fiscal Quarter and Fiscal Year ended March 31, 2009 and the First Fiscal Quarter ended June 30, 2009 on September 1, 2009 2Cell Therapeutics, Inc. Announces Institutional Investor Purchases $30 Million of Preferred Stock and Warrants 2Cell Therapeutics, Inc. Announces Institutional Investor Purchases $30 Million of Preferred Stock and Warrants 3
... (100+kb), fosmid (40kb), and large plasmid insert ... othe BAC vector. On command 20-50 fold ... recombinant DNA purification. Available with blue-white screening ... for the highest insert stability. Kits include ...
... System is used in conjunction ... PCR of problematic and/or GC-rich ... Solution with 10X PCRX Amplification ... broader magnesium concentration broader annealing ...
6-carboxy-2',4,4',5',7,7'-hexachlorofluorescein, succinimidyl ester (6-HEX, SE) *single isomer*...
Mouse Exodus 2 - 12kDa...
Biology Products: