Navigation Links
Eve Marder to receive the $500,000 Gruber Neuroscience Prize
Date:6/10/2013

Eve Marder, PhD, a professor of neuroscience at Brandeis University, is the recipient of the 2013 Neuroscience Prize of The Gruber Foundation. Marder is being honored with this prestigious international award for her pioneering contributions to the understanding of neural circuits, particularly how the properties and dynamics of neural circuits give rise to specific behaviors.

The award will be presented to Marder in San Diego on Nov. 10 at the 43rd annual meeting of the Society for Neuroscience.

"Eve Marder has made a number of remarkable and groundbreaking discoveries that have fundamentally changed our understanding of how neural circuits operate and produce behavior," says Carol Barnes, chair of the Selection Advisory Board to the Neuroscience Prize. "She has also been an exceptional leader outside the laboratory, working tirelessly to bring people together to improve scientific research, policy, and education."

Marder's seminal discoveries about neural circuits have arisen from her research on a very small nervous system, the stomatogastric ganglion (STG) of lobsters and crabs. The STG system controls the rhythmic muscle contractions that grind and move food through the crustaceans' gut, and is considered similar to the neural circuits that control breathing and other rhythmic functions in humans. Early in her career, Marder revealed that the STG was not "hard-wired" to produce a single pattern of output, but that it was a remarkably plastic circuitry that could change both its parameters and function in response to various neuromodulators while still maintaining its morphologic connectivity. This discovery marked a paradigm shift in how scientists viewed the architecture and function of neural circuits, including those in the human brain. It revolutionized the study of neuromodulators.

Marder is also recognized for helping to pioneer the expansion of theoretical neuroscience, which uses computational and mathematical tools to quantify what nervous systems do and how they operate. She collaboratively developed a major experimental tool known as the dynamic clamp, which allows scientists to introduce mathematically modeled synaptic or other conductances into biological neurons. The device is now used worldwide for the study of neural systems at the cellular and circuitry levels.

More recently, Marder's research has focused on how neural circuits maintain stability, or homeostasis, over long periods of time despite constantly reconfiguring themselves. This research has broad implications for the study of many neurological diseases linked to dysfunctional neural circuitry, such as schizophrenia, depression, epilepsy, post-traumatic stress disorder (PTSD), and chronic pain.

"So much of what we know about the complexity and flexibility of the mechanisms used by neural circuits to impact behavior can be traced directly back to Marder's landmark research," says Erwin Neher, Nobel Laureate and member of the Selection Advisory Board to the Neuroscience Prize. "She has had a tremendous impact across the field of neuroscience, and is very much deserving of this award."


'/>"/>

Contact: A. Sarah Hreha
info@gruber.yale.edu
203-432-6231
Yale University
Source:Eurekalert

Related biology news :

1. In search for a vaccine, IU biologist receives $2.3 million to explore chlamydia genomics
2. WHOI researchers, collaborators receive $1.4 million grant to study life in oceans greatest depths
3. Renowned geneticist R. Rodney Howell receives ACMG Foundation Lifetime Achievement Award
4. UF receives $1 million from Keck Foundation to study mechanisms of inherited disease
5. Gladstone scientist Warner C. Greene receives Washington University School of Medicine Alumni Award
6. Carnegies Wolf B. Frommer receives Bogorad Award for Excellence in Plant Biology
7. UC Riverside plant cell biologist receives top scientific honor
8. UC Riverside receives grant for global health and development research
9. Washington University receives $8 million to lead international childhood malnutrition effort
10. SRI Sarnoffs Iris on the Move® N-Glance™ Identification System Receives Lenel Factory Certification
11. SF State biology department receives $1.5 million to support science teaching
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... , April 11, 2017 NXT-ID, ... security technology company, announces the appointment of independent Directors Mr. ... to its Board of Directors, furthering the company,s corporate ... ... NXT-ID, we look forward to their guidance and benefiting from ...
(Date:4/5/2017)... 2017 KEY FINDINGS The global ... a CAGR of 25.76% during the forecast period of ... factor for the growth of the stem cell market. ... MARKET INSIGHTS The global stem cell market is ... geography. The stem cell market of the product is ...
(Date:3/30/2017)... The research team of The Hong Kong Polytechnic University (PolyU) ... ground breaking 3D fingerprint minutiae recovery and matching technology, pushing contactless ... use in identification, crime investigation, immigration control, security of access and ... ... A research team led by Dr Ajay Kumar ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... LAGUNA HILLS, Calif. , Oct. 11, 2017 ... London (ICR) and University of ... prognostic tool to risk-stratify patients with multiple myeloma (MM), in ... nine . The University of Leeds ... by Myeloma UK, and ICR will perform the testing services ...
(Date:10/11/2017)... TX (PRWEB) , ... October 11, 2017 , ... ... August compared the implantation and pregnancy rates in frozen and fresh in ... contribution of progesterone and maternal age to IVF success. , After comparing the ...
(Date:10/10/2017)... ... ... San Diego-based team building and cooking events company, Lajollacooks4u, has unveiled a ... new look is part of a transformation to increase awareness, appeal to new markets ... It will also expand its service offering from its signature gourmet cooking classes and ...
(Date:10/10/2017)... (PRWEB) , ... October 10, 2017 , ... ... Science Center’s FirstHand program has won a US2020 STEM Mentoring Award. Representatives of ... award for Excellence in Volunteer Experience from US2020. , US2020’s mission is to ...
Breaking Biology Technology: