Navigation Links
European membrane expertise to focus on new treatments for human diseases
Date:3/18/2008

A new 15 million Euro project led by the University of Leeds aims to find novel treatments for many human diseases by bringing together the leading European experts in membrane proteins.

The project the European Drug Initiative for Channels and Transporters (EDICT) will target about 80 proteins, which play an important role in human diseases as varied as diabetes, heart disease, neuropsychiatric disorders like epilepsy and depression, osteoporosis, stomach ulcers and cataracts.

Membrane proteins are key to every process in the human body, channelling ions or transporting chemicals and so are ideal targets for new treatments. Infections by pathogenic bacteria, yeasts and parasites also involve their own membrane proteins, which can be specific targets for development of new drugs and antibiotics.

The research is mainly funded by the European Commission, involves twenty-seven partners from twelve countries including two Nobel Laureates - and is set to last four years.

Coordinating the project is Peter Henderson, Professor of Biochemistry and Molecular Biology from Leeds Faculty of Biological Sciences.

Membrane proteins are seen by many as the next potential source of drug development, and so the EC is keen to fund research in this area, he said. However, they are difficult to study and are poorly understood, though the recent sequencing of the human and other genomes show they make up about one third of all proteins in all organisms, including humans.

At the moment, few groups of membrane proteins are being seriously investigated by the pharmaceutical industry, so this project will help to fill that gap. By bringing together the best scientists in this challenging field from all over Europe, we hope to make a real advance towards new treatments for key diseases.

Industry has also seen the benefit of bringing such expertise together under one umbrella and working with the academics will be pharmaceu
'/>"/>

Contact: Jo Kelly
jokelly@campuspr.co.uk
44-113-258-9880
University of Leeds
Source:Eurekalert

1

GOOD

Page: 1 2

Related biology news :

1. ESFs European ice core project EPICA receives prestigious Descartes Prize
2. First European Lung Cancer Conference
3. European Union forests expanding, absorbing carbon at surprisingly high rate: study
4. IdentiPHI Opens Paris Office to Boost European Sales and Support
5. Hot spots the key to controlling European carp in Australia
6. European lead in reading past climates from ice cores
7. Three-way mating game of North American lizard found in distant European relative
8. 2 French scientists win European award for communication
9. Last chance for media to register for ECCO 14 -- the European Cancer Conference
10. Researchers develop better membranes for water treatment, drug delivery
11. New membrane strips carbon dioxide from natural gas faster and better
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... DNA around nucleosomes in the cell nucleus makes ... Ludwig-Maximilians-Universitaet (LMU) in Munich now describes a mechanism ... from nucleosomes for transcription. , In higher organisms ... nucleus, wrapped around disk-shaped particles called nucleosomes, each ... proteins and accommodating two loops of DNA. Packed ...
(Date:5/23/2013)... medics have succeeded in treating cerebral palsy with autologous ... damage, a 2.5 year old boy had been in ... survival. Just two months after treatment with the cord ... the following months, the child learned to speak simple ... from a Korean study, dispel the long-held doubts about ...
(Date:5/23/2013)... pathogens are growing increasingly resistant to the conventional antibiotics ... scientists has synthesized a potent new class of compounds ... , Writing online in the Journal of the ... of Wisconsin-Madison chemistry Professor Helen Blackwell describes agents that ... Staphylococcus aureus , a bacterium at the root of ...
Breaking Biology News(10 mins):Biochemistry: Unspooling DNA from nucleosomal disks 2First successful treatment of pediatric cerebral palsy with autologous cord blood 2University of Wisconsin chemists find new compounds to curb staph infection 2
... like Celecoxib have come under scrutiny lately due to ... fruit fly and rat models, researchers reveal another adverse ... interestingly, this effect is independent of the COX-2 enzyme. ... doses on the heart rate of Drosophila, a good ...
... History of Marine Animal Population , Edited by ... available on: http://shop.earthscan.co.uk/ProductDetails/mcs/productID/821 , Violent confrontations ... feature of the intense hunt for sponges on Floridas ... were the sponges themselves. Human harvesters not only depleted ...
... Society (ACS) News Service Weekly PressPac with news from ACS ... individual journal or the American Chemical Society as the source ... EXCEPT ARTICLE #5, which is embargoed for 9 A. M., ... IMMEDIATE RELEASE Seagull blood shows promise ...
Cached Biology News:Oceans Past: A Guide to Oceans Future 2Oceans Past: A Guide to Oceans Future 3Oceans Past: A Guide to Oceans Future 4Oceans Past: A Guide to Oceans Future 5Oceans Past: A Guide to Oceans Future 6American Chemical Society's weekly PressPac -- Jan. 9, 2008 2American Chemical Society's weekly PressPac -- Jan. 9, 2008 3American Chemical Society's weekly PressPac -- Jan. 9, 2008 4American Chemical Society's weekly PressPac -- Jan. 9, 2008 5American Chemical Society's weekly PressPac -- Jan. 9, 2008 6American Chemical Society's weekly PressPac -- Jan. 9, 2008 7American Chemical Society's weekly PressPac -- Jan. 9, 2008 8American Chemical Society's weekly PressPac -- Jan. 9, 2008 9
(Date:5/23/2013)... -- Rahal Letterman Lanigan Racing (RLL) and StemCyte, Inc., a ... and therapeutics, announced today that StemCyte has become an ... car driven by James Jakes . ... 2013 season.   StemCyte, Inc. and Rahal Letterman ... umbilical cord blood banking and its educational initiative ,Stars ...
(Date:5/23/2013)... , May 23, 2013  Saddleback Memorial Medical Center ... became the first hospital on the West Coast to ... new surgical option provides women with a state-of-the-art, minimally ... Marc Winter , M.D., a highly regarded ... and medical director of minimally invasive surgery at Saddleback ...
(Date:5/23/2013)... , May 23, 2013 Z Trim ... value-added ingredients to a variety of industries, announced that ... a panel discussion at this year,s National Restaurant Association ... 2013, on behalf of the Research Chefs Association.  Chef ... Restaurants: The Good, the Bad and the Ugly," joining ...
(Date:5/23/2013)... , May 23, 2013  Verenium Corporation (Nasdaq: ... on the development and commercialization of high-performance enzymes, today ... Financial Officer, will present at two upcoming conferences. ... will present at the Second Annual Marcum LLP Microcap ... Hyatt Hotel in New York City.  The presentation is ...
Breaking Biology Technology:StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 2StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 3Saddleback Memorial Surgeon First on the West Coast to Perform Single-Site Robotic Hysterectomy 2Saddleback Memorial Surgeon First on the West Coast to Perform Single-Site Robotic Hysterectomy 3Z Trim's Chef Erin Ryan sits on Expert Panel at NRA Show 2Z Trim's Chef Erin Ryan sits on Expert Panel at NRA Show 3Verenium To Present At Two Upcoming Conferences 2Verenium To Present At Two Upcoming Conferences 3
... PCR cloning with pcmv-script PCR cloning kit , ... Quinn,Lu ,Stratagene Cloning Systems, Inc. , , Stratagene ... cloning,strategy by introducing a new vector for high-efficiency cloning ... PCR,cloning kit uses a ...
... transfection reagent: A proven choice , ... transfection reagent offers,improved, consistent ... in,suspension. In this article, we summarize the results ... reagent. Optimizing transfection,conditions is a critical, preliminary step ...
... software aids image acquisition and processing , Michelle Cayouette *Michael Steege * ... Eagle Eyes Still Video System shown with Darkroom ... Stratagenes new Eagle Sight software version 3.0 allows researchers , ... information from stained , nucleic acids ...
Cached Biology Technology:Mammalian Expression Vector for Efficient Cloning of PCR Fragments 2Mammalian Expression Vector for Efficient Cloning of PCR Fragments 3Mammalian Expression Vector for Efficient Cloning of PCR Fragments 4Versatile Transfection Reagent Offers Low Toxicity and Consistent,Performance 2Versatile Transfection Reagent Offers Low Toxicity and Consistent,Performance 3Versatile Transfection Reagent Offers Low Toxicity and Consistent,Performance 4Versatile Transfection Reagent Offers Low Toxicity and Consistent,Performance 5Versatile Transfection Reagent Offers Low Toxicity and Consistent,Performance 6Versatile Transfection Reagent Offers Low Toxicity and Consistent,Performance 7Keys to Successful Densitometry 2Keys to Successful Densitometry 3Keys to Successful Densitometry 4Keys to Successful Densitometry 5Keys to Successful Densitometry 6
Microlite 1+ 1x12 Strip assembled, flat bottom; the ideal vessel for low signal luminescent reactions, offering medium binding with enhanced dynamic range, extra high reflectivity and minimal cross t...
Immulon 4 HBX 1x12 Strip, flat bottom; high binding extra surface with special resin and irradiation, offers maximum protein uptake....
... regulator and pressurized syringe holder for any researcher ... flow rate Microinjecting Fine microliter delivery ... added to any new or existing perfusion rig ... homemade. Connect to house air or a compressor ...
...
Biology Products: