Major transformations in biomedical science are on the horizon with the establishment of the world-class Integrated Structural Biology Infrastructure (Instruct) in support of European biomedical research.
The European Strategy Forum of Research Infrastructures (ESFRI) is involved in establishing about 40 such infrastructures, seven of them in biomedical sciences. Instruct is one such biomedical project, whose aim is to provide pan-European user access to state-of-the-art equipment, technologies and manpower in cellular structural biology. This will allow Europe to maintain a competitive edge and play a leading role in this vital research area.
The Weizmann Institute of Science, together with Tel Aviv University, has been chosen as one of the seven Core Centres, joining prestigious institutions in the UK, Italy, France and Germany.
"Structural Biology is a scientific area in which Israeli scientists have been leading for many years, as evidenced by Weizmann Institute's Prof. Ada Yonath, who won a Nobel Prize in 2009 for her pioneering work on solving the structure of ribosomes," says the Institute's Prof. Joel Sussman, Director of Israel's Instruct Core Centre.
Crucial to understanding how the living cell functions is knowledge of the three-dimensional structures of its proteins and nucleic acids, how these interact with one another, and their arrangement and dynamics within the cell. But no single discipline alone is able to decipher this. "In addition to the Weizmann Institute having developed world-class research programs in several of the disciplines relevant to Instruct, including electron microscopy, mass spectroscopy, X-ray crystallography, NMR, bioinformatics and structural proteomics, the Israel Structural Proteomics Center (ISPC) has played a synergistic role in integrating and coordinating all these various disciplines," says Sussman. The ISPC was established by scientists from the Weizmann Institute, with Sussman
|Contact: Yivsam Azgad|
Weizmann Institute of Science