Navigation Links
Essential nutrient found in eggs may help lower risk of neural tube defects
Date:8/12/2009

Park Ridge, Ill. (August 12, 2009) Research published online in the journal Epidemiology found that higher levels of total blood choline are associated with a 2.5-fold reduction in risk for neural tube birth defects (NTDs).(1) NTDs are birth defects of the brain and spinal cord, and the two most common NTDs are spina bifida and anencephaly. According to the Centers for Disease Control (CDC), an estimated 3,000 pregnancies in the U.S. are affected by NTDs each year.(2,3) This study adds to the growing body of evidence demonstrating the important role of choline in fetal development.

Study Findings
The Epidemiology study investigated blood samples from more than 180,000 pregnant women and found 80 cases of NTDs. Researchers compared the blood samples to samples from 409 controls without birth defects and examined the specimens for markers including choline, folate, homocysteine, methionine and betaine among others. The researchers observed:

  • a 2.5-fold reduction in risk for NTDs with the highest blood choline levels
  • no other significant differences between the two study groups for any of the other blood markers

In the research discussion, the investigators note that the cause of NTDs is very complex and that supplementation of the food supply with folic acid, though effective, is only part of the solution. "This study is exciting because it offers new clues for preventing serious birth defects like spina bifida," said Dr. Gary M. Shaw, co-author of the study and professor of pediatrics at Stanford University School of Medicine. "This research should be repeated in other settings so we can learn more about the best nutrition advice to give pregnant women."

The Benefits of Choline
Choline is an essential nutrient needed for many of life's most basic functions including brain and nerve function, liver metabolism, the transportation of nutrients and the normal functioning of every cell in the body. Adequate choline intake is especially important for pregnant and breastfeeding women because it has been shown to influence prenatal and infant brain and spinal cord development as well as lifelong memory and learning functions. There is a high rate of choline transfer from mother to fetus and breast milk is also rich in choline, so meeting maternal choline needs is very important.

Emerging research also shows that choline may have additional benefits in areas such as:

  • Memory function: Animal studies have demonstrated that age-associated memory decline seems to be delayed in offspring when mothers' diets are supplemented with choline during pregnancy.(4)
  • Breast cancer prevention: A study funded by a grant from the National Institutes of Health (NIH) found that the risk of developing breast cancer was 24 percent lower among women with the highest intake of choline compared to women with the lowest intake.(5)
  • Cardiovascular health: Choline has been shown to play an important role in reducing homocysteine, an amino acid in the blood that may be associated with an increased risk of chronic inflammation, which is considered a risk factor for heart disease.(6)

Closing the Choline Consumption Gap
Despite its important role in the body, only one in 10 Americans is meeting the Adequate Intake (AI) guidelines for choline.(7) "Most people don't know how important choline is for their bodies, or how easy it is to get the choline you need from food," explains Elizabeth Ward, a registered dietitian in private practice and author of the new book "Expect the Best: Your Guide to Healthy Eating Before, During, & After Pregnancy." Ward, who is not affiliated with Stanford, also notes "One large egg can help meet roughly one-quarter of the recommended daily intake of choline for men, women and women who are pregnant or nursing."

For those looking to add more choline to their diet, Ward offers these additional tips:

  • Focus on Foods: Most prenatal and regular multivitamins provide far less than the AI for choline. The easiest way to get the choline you need is by eating a balanced diet rich in foods that contain choline such as eggs, lean beef, salmon, cauliflower, milk and peanut butter.
  • Don't Skip the Yolk: Choline is found exclusively in the egg yolk, and one yolk contains 125 milligrams of choline. The egg yolk also contains nearly half the protein in an egg, and the yolk is the only place you'll find the nutrients lutein and zeaxanthin which are important antioxidants related to eye health. While eggs contain a small amount of lutein and zeaxanthin, research suggests that these nutrients may be more bioavailable from eggs than from richer sources.


'/>"/>

Contact: Egg Nutrition News Bureau
info@eggnutrition.org
312-233-1211
Egg Nutrition News Bureau
Source:Eurekalert

Related biology news :

1. Mystery E. coli genes essential for survival of many species
2. New guide to tropical seedlings: Essential to climate change research
3. New edition available for essential virology reference
4. New lab manual focuses on essential methods for purifying and characterizing proteins
5. Rethinking who should be considered essential during a pandemic flu outbreak
6. Researchers find an essential gene for forming ears of corn
7. New study reveals large scale conservation essential
8. Substantial improvement in essential cheap solar cell process
9. Trainor Lab characterizes gene essential for prenatal development of nervous system
10. Earth Observation essential for geohazard mitigation
11. ESA to provide essential launch control services to EUMETSAT
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/19/2016)... , UAE, April 20, 2016 ... be implemented as a compact web-based "all-in-one" system solution ... the biometric fingerprint reader or the door interface with ... of modern access control systems. The minimal dimensions of ... ID readers into the building installations offer considerable freedom ...
(Date:4/15/2016)... 15, 2016 Research and ... Biometrics Market 2016-2020,"  report to their offering.  , ... , ,The global gait biometrics market is expected ... the period 2016-2020. Gait analysis generates ... be used to compute factors that are not ...
(Date:4/13/2016)... 2016  IMPOWER physicians supporting Medicaid patients in ... clinical standard in telehealth thanks to a new partnership ... platform, IMPOWER patients can routinely track key health measurements, ... index, and, when they opt in, share them with ... a local retail location at no cost. By leveraging ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... June 24, 2016  Regular discussions on a range of ... between the two entities said Poloz. Speaking at ... Ottawa , he pointed to the country,s inflation target, ... government. "In certain ... institutions have common economic goals, why not sit down and ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... pleased to announce the launch of their brand, UP4™ Probiotics, into Target stores ... 35 years, is proud to add Target to its list of well-respected retailers. ...
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... ... Plate® YM (Yeast and Mold) microbial test has received AOAC Research Institute approval ... of microbial tests introduced last year,” stated Bob Salter, Vice President of Regulatory ...
(Date:6/23/2016)... ... June 23, 2016 , ... STACS DNA Inc., the ... at the Arkansas State Crime Laboratory, has joined STACS DNA as a Field Application ... team,” said Jocelyn Tremblay, President and COO of STACS DNA. “In further expanding our ...
Breaking Biology Technology: