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'Escaped' proteins add to hearing loss in elderly, UF researchers find
Date:11/10/2009

t interventions at what combination and what dose."

Caloric restriction, another way to reduce oxidative damage, has previously been shown to extend life and prevent age-related hearing loss in the type of mice used in the study. With the new findings, the investigators propose that one of the ways that restriction of calories acts is by reducing the level of cell death that is induced by the protein Bak.

"This extends research into life extension by caloric restriction into a whole new area that hasn't been looked at before," said Huber Warner, Ph.D., associate dean for research a University of Minnesota College of Biological Sciences and former director of the biology of aging program at the National Institute on Aging, who was not involved in the study. "The work shows that rather than caloric restriction just having an overall effect on metabolism of nutrients, bak modulation can have segmental effects on particular physical systems that have age-related problems in humans."


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Contact: Czerne M. Reid
czerne@ufl.edu
352-273-5814
University of Florida
Source:Eurekalert

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