Navigation Links
Epigenetics mechanism may help explain effects of mom's nutrition on her children's health
Date:3/11/2013

This press release is available in Spanish.

Pioneering studies by U. S. Department of Agriculture-funded research molecular geneticist Robert A. Waterland are helping explain how the foods that soon-to-be-moms eat in the days and weeks around the time of conceptionor what's known as periconceptional nutritionmay affect the way genes function in her children, and her children's health.

In an early study, Waterland and co-investigators examined gene function of 50 healthy children living in rural villages in the West African nation of The Gambia. The study has shaped some of Waterland's current research into the effects of nutrition on what geneticists refer to as epigenetic mechanisms. Those mechanisms can impact, for example, the levels at which an everyday biochemical process, DNA methylation, occurs at regions of certain genes. DNA methylation is essential for cell development and for stabilizing cell function.

In the West Africa study, Waterland and co-researchers found that levels of DNA methylation were higher at regions of five genes in children conceived during the peak rainy season months of August and September, when food would typically have been less available to their mothers.

According to Waterland, two of the five genes in which elevated DNA methylation occurred warrant further study because they are associated with risk of disease. Specifically, the SLITRK1 gene is associated with Tourette's syndrome, and the PAX8 gene is linked to hypothyroidism.

The researchers attributed the epigenetic variation to dramatic seasonal differences in the kinds and amounts of foods available in the three subsistence-farming villages that were the focus of the study.

An article in the March 2013 issue of Agricultural Research magazine tells more.

Contact: Marcia Wood
marcia.wood@ars.usda.gov
301-504-1662
United States Department of Agriculture - Research, Education and Economics
Source:Eurekalert

Page: 1 2

Related biology news :

1. Life experiences put their stamp on the next generation: New insights from epigenetics
2. Epigenetics shapes fate of brain vs. brawn castes in carpenter ants
3. Study finds epigenetics, not genetics, underlies homosexuality
4. Sick from stress? Blame your mom… and epigenetics
5. Not by DNA alone: How the epigenetics revolution is fostering new medicines
6. Epigenetics and epidemiology -- hip, hype and science
7. IRB Barcelona researchers discover mechanism that regulates steroid hormone production in Drosophila
8. Researchers explain a key developmental mechanism for the first time in plants
9. Novel storage mechanism allows command, control of memory
10. Mechanisms regulating inflammation associated with type 2 diabetes, cancer identified
11. Researchers at IRB Barcelona discover a general mechanism that accelerates tumor development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... evidence has demonstrated that transplantation of mesenchymal stem cells ... or mouse models of Alzheimer,s disease (AD) and improve ... ischemia. Few studies are reported on the therapeutic effect ... AD and on the effect on oxidative injury and ... Yan and her team, School of Life Sciences, Tsinghua ...
(Date:7/11/2014)... that cannabinoid receptor type 1 can inhibit ... and reduce neurotransmitter release. However, some scholars ... increase extracellular Ca2+ influx and increase neurotransmitter ... Tongji Hospital Affiliated to Tongji Medical College, ... used whole cell voltage-clamp and calcium imaging ...
(Date:7/11/2014)... brains of all vertebrates, information is transmitted through ... chemical signal to be passed from one brain ... most abundant type of synapse, can be either ... learning, memory, perception and cognition, and the balance ... function. For instance, every time we learn ...
Breaking Biology News(10 mins):Blame it on the astrocytes 2
... May 3, 2010-Conventional agriculture production relies heavily on fossil ... a low cost. However, the uncertain future of fossil ... energy efficiencies in other cropping systems. Most of ... of corn and soybean with heavy inputs of fertilizer, ...
... May 3, 2010 Genes interact in complex networks that ... through relationships. Researchers are now discovering how biological networks ... published today in Genome Research ( www.genome.org ), ... shedding light on how interactions go awry in disease. ...
... May 2 Scientists at the University of Pittsburgh School ... a catch of new mediators that not only can explain ... novel treatments for a host of diseases linked to inflammatory ... of Nature Chemical Biology . There is strong ...
Cached Biology News:Reducing fossil energy use on the farm 2Reducing fossil energy use on the farm 3MicroRNA network study implicates rewired interactions in cancer 2Pitt pharmacologists go on a molecular fishing trip and hook prize catch 2
(Date:7/10/2014)... Los Angeles, CA (PRWEB) July 10, 2014 ... Analytical and Bioanalytical techniques during 18-20 August, 2014 at ... to critically review the recent developments in Analytical & ... across the globe. , Speaking on this occasion, Dr. ... that Analytica Acta conference is a remarkable one ...
(Date:7/10/2014)... , July 10, 2014  Kainos Capital, a firm ... today announced that it has acquired the Slim-Fast brand ... the business. Terms of the transaction were not disclosed. ... meal replacement business that markets ready-to-drink shakes, powders, bars ... America and in the United ...
(Date:7/10/2014)... help in the fight against terrorism with the creation ... explosives with the use of light and special glass ... Actuators B: Chemical , the researchers describe a novel ... as low as 6.3 ppm (parts per million). It ... , "Traditionally explosives detection has involved looking for metals ...
(Date:7/10/2014)... batteries that power our laptops and electric vehicles could ... charge with the help of a sponge-like silicon material. ... the graphite traditionally used in one of the battery,s ... energy storage capacity of graphite. A paper describing the ... today in Nature Communications . , "Silicon has ...
Breaking Biology Technology:A Critical Review of Analytical Techniques for Improved Living Standards 2A Critical Review of Analytical Techniques for Improved Living Standards 3A Critical Review of Analytical Techniques for Improved Living Standards 4Kainos Capital Acquires Slim-Fast From Unilever 2Detecting trace amounts of explosives with light 2Silicon sponge improves lithium-ion battery performance 2Silicon sponge improves lithium-ion battery performance 3
... the diuretic hydrochlorothiazide (HCTZ) in ... in significant additional blood pressure reductions compared to either drug alone ... or more, medicines - single-tablet combinations simplify treatment by reducing ... number of pills patients take, EAST ...
... Named ,Illinois Rising Stars, CHICAGO, Jan. 18 ... property law firms in the United States, is,pleased to ... "Illinois,Super Lawyers" for 2008 in a survey conducted by ... designated "Rising Stars" in,Illinois., Meredith Martin Addy, chair ...
... Jan. 18 Abbott (NYSE: ABT ),announced today ... for its fully automated HTLV-I/HTLV-II blood screening test,for use ... for use by,laboratories to screen individual donations of blood ... Type I and/or human T --,lymphotropic virus Type II ...
Cached Biology Technology:Video and Photo: Tekturna HCT(R), a Single-tablet Combination of Tekturna(R)* and a Diuretic, Receives US Approval for Treatment of High Blood Pressure 2Video and Photo: Tekturna HCT(R), a Single-tablet Combination of Tekturna(R)* and a Diuretic, Receives US Approval for Treatment of High Blood Pressure 3Video and Photo: Tekturna HCT(R), a Single-tablet Combination of Tekturna(R)* and a Diuretic, Receives US Approval for Treatment of High Blood Pressure 4Video and Photo: Tekturna HCT(R), a Single-tablet Combination of Tekturna(R)* and a Diuretic, Receives US Approval for Treatment of High Blood Pressure 5Twenty-One Brinks Hofer Gilson & Lione Attorneys Named 2008 'Illinois Super Lawyers' 2Abbott Announces Approval of First Fully Automated Blood Screening Test for HTLV-I/HTLV-II 2Abbott Announces Approval of First Fully Automated Blood Screening Test for HTLV-I/HTLV-II 3