Navigation Links
Epigenetics could help researchers determine any risks associated with low-dose radiation
Date:2/1/2010

There remains a lack of consensus amongst the medical and scientific communities about any cancer risk from low level radiation, particularly low-dose radiation delivered from computed tomography (CT) scans. However, the study of epigenetics may play a role in determining whether or not future trends of diseases can in fact be linked to utilization of CT, according to an article in the February issue of the Journal of the American College of Radiology (JACR).

The term epigenetics refers to changes in the phenotype (appearance) or gene expression caused by mechanisms other than changes in the underlying DNA sequence. These changes may remain through cell divisions for the remainder of the cell's life and may also last for multiple generations.

"Radiation safety is, without a doubt, a large concern for practicing radiologists today," said Shella Farooki, MD, author of the article and radiologist and director of research for Columbus Radiology Corp in Columbus, OH. "However, the current focus does not account for the possibility of harm to future generations from radiation delivered today. I believe that it is equally, if not more important, to consider potential harm to the patient's offspring and their offspring's offspring," she said.

"The effects of ionizing radiation have been demonstrated in neighboring cells (non-targeted radiation), known as the bystander effect. In addition, ionizing radiation effects have been shown to span generations, resulting in heritable defects in mice. However, we need to bridge the gap between understanding the epigenome functionality and radiation exposure before assuming anything," said Farooki.

"In 2008, the National Institutes of Health (NIH) announced that $190 million had been earmarked for epigenetics research over the next five years," she said. In announcing the funding, government officials noted that epigenetics had the potential to explain mechanisms of aging, hu
'/>"/>

Contact: Heather Curry
hcurry@acr-arrs.org
703-390-9822
American College of Radiology / American Roentgen Ray Society
Source:Eurekalert

Page: 1 2

Related biology news :

1. UD leads $5.3-million research project on rice epigenetics
2. UD leads $5.3-million research project on rice epigenetics
3. Environmental epigenetics has potential for preventing and treating disease
4. The epigenetics of increasing weight through the generations
5. Ali Shilatifard and colleagues aim to clarify the definition of epigenetics
6. New nucleotide could revolutionize epigenetics
7. New piece found in the puzzle of epigenetics
8. Newly created cancer stem cells could aid breast cancer research
9. Obesity and lack of exercise could enhance the risk of pancreatic cancer
10. Finding that 1-in-a-billion that could lead to disease
11. 60 second test could help early diagnosis of common brain diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... La 10 th International Conference on Genomics ... 22 al 25 de octubre de 2015 en ... conferencia celebra su décimo aniversario. Desde su inauguración en el ... reuniones anuales más influyentes del mundo en el campo ,ómico, ... y mejores a nivel científico. ICG-10 se ...
(Date:7/30/2015)... 2015 Cellecta, Inc., a U.S.-based provider ... and biomarker discovery, announced the release of its ... all human protein coding genes. CRISPR technology enables ... gene,s function. Cellecta,s new Human Whole Genome CRISPR ... so that researchers can investigate in a single ...
(Date:7/23/2015)... July 23, 2015 Research and Markets ... the "Global Outlook of the Biometrics Industry ... The global biometrics market is likely ... commercial applications owing to the uptake of multiple ... transformation that enhances the growth of biometrics in ...
Breaking Biology News(10 mins):La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 2La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 3CELLECTA, INC. Announces Launch of Human Whole Genome CRISPR Knockout Library 2Global Outlook of the Biometrics Industry 2015 2Global Outlook of the Biometrics Industry 2015 3
... the nature of crowds playing Foldit called some strategies ... methods already used by protein scientists., Gamers made headlines ... central to research on AIDS. Today, in a ... National Academy of Sciences, University of Washington researchers ...
... 2011 AVT, Inc. (formerly Automated Vending Technologies) (Ticker: ... provide a new line of Secure Automated Retailing Systems ... This new system provides extra security for automated ... customer is critical. AVT worked with ...
... characterize the genes involved in wood formation in poplar trees ... wood as a feedstock for biofuels production. "This ... work of other biofuels researchers who develop better and more ... Beers, professor of horticulture and the lead investigator on the ...
Cached Biology News:Paper uncovers power of Foldit gamers' strategies 2Paper uncovers power of Foldit gamers' strategies 3AVT Partners with MedBox to Provide New Biometric Fingerprint Recognition for Secure Automated Retailing 2Genomics of wood for biofuels production investigated 2
(Date:7/30/2015)... ... July 30, 2015 , ... ... field clinical study of its canine osteoarthritis stem cell product, currently under development ... City, KS) and will be marketed in the US by Aratana. This product, ...
(Date:7/30/2015)... customers across the globe, ISN improves the efficiency and effectiveness of contractor management systems. ... and reliable contractors in over 80 countries. ... ... Over 60,000 Worldwide Customers In More Than 80 Countries ... Headquartered in Dallas, TX , ISN has additional offices in ...
(Date:7/30/2015)... Pa. , July 30, 2015  Discovery ... that it has received the second $1.0M tranche ... Innovation Research (SBIR) grant valued at up to ... company,s aerosolized KL4 surfactant as a potential medical ... injury.  Discovery Labs was awarded an initial $1.0 ...
(Date:7/29/2015)... Sanofi, a global and ... quarter of 2015. CEO Olivier Brandicourt ... in different businesses. Watch video interview ... Topics covered in the interview include:  ... Performance drivers - Diabetes ...
Breaking Biology Technology:VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 2VetStem Biopharma Successfully Completes Large Milestone Efficacy Study for its Flagship Canine Osteoarthritis Stem Cell Product 3ISN Reaches Over 60,000 Worldwide Customers 2ISN Reaches Over 60,000 Worldwide Customers 3Discovery Labs Receives $1.0 million under an SBIR Grant in Continuing Support of the Development of Aerosolized KL4 Surfactant to Address Radiation-Induced Lung Injury 2Discovery Labs Receives $1.0 million under an SBIR Grant in Continuing Support of the Development of Aerosolized KL4 Surfactant to Address Radiation-Induced Lung Injury 3
... U.S. Secretary of Health and Human Services Tommy Thompson has ... , a provider of information systems for high-acuity care areas ... room and the intensive care unit. , ,Thompson began his ... Wisconsin's state Assembly. He was elected assistant Assembly minority leader ...
... has approved a $500,000 start-up grant for the ... group for classified, defense-related projects. , ,The ... also initially include the UW System, the Medical ... and the Milwaukee School of Engineering. , ,The ...
... National LambdaRail Two UW-Madison computer science professors, ... have been named to the National LambdaRails Networking Researching ... the high-speed fiber optic networks research goals. , ,The ... educational groups across the country, which over the past ...
Cached Biology Technology:Wisconsin consortium aims for defense business 2Two UW-Madison professors named to National LambdaRail Networking Research Council 2
... enables complete conversion of unmethylated cytosines ... hours. The highly sensitive method utilizes ... and a spin-column-based purification and desulfonation ... results for all downstream applications. The ...
... Shimadzus GCMS-QP2010s Gas Chromatograph/Mass Spectrometer, ... of the GCMS-QP2010 Plus, offers high ... with an excellent performance-to-cost ratio. Like ... patented constant linear velocity for optimum ...
... enterprise microarray informatics platform for microarray data storage, ... and use it forever without paying ongoing license ... Acuity has all the analysis tools you need ... quality control statistics and normalization, all the way ...
... Pro is the industry standard microarray image ... of imaging and analysis tools, visualizations, automation ... Pro is included with every GenePix scanner, ... third-party scanners and all types of arrays. ...
Biology Products: