Navigation Links
Epigenetics could help researchers determine any risks associated with low-dose radiation
Date:2/1/2010

There remains a lack of consensus amongst the medical and scientific communities about any cancer risk from low level radiation, particularly low-dose radiation delivered from computed tomography (CT) scans. However, the study of epigenetics may play a role in determining whether or not future trends of diseases can in fact be linked to utilization of CT, according to an article in the February issue of the Journal of the American College of Radiology (JACR).

The term epigenetics refers to changes in the phenotype (appearance) or gene expression caused by mechanisms other than changes in the underlying DNA sequence. These changes may remain through cell divisions for the remainder of the cell's life and may also last for multiple generations.

"Radiation safety is, without a doubt, a large concern for practicing radiologists today," said Shella Farooki, MD, author of the article and radiologist and director of research for Columbus Radiology Corp in Columbus, OH. "However, the current focus does not account for the possibility of harm to future generations from radiation delivered today. I believe that it is equally, if not more important, to consider potential harm to the patient's offspring and their offspring's offspring," she said.

"The effects of ionizing radiation have been demonstrated in neighboring cells (non-targeted radiation), known as the bystander effect. In addition, ionizing radiation effects have been shown to span generations, resulting in heritable defects in mice. However, we need to bridge the gap between understanding the epigenome functionality and radiation exposure before assuming anything," said Farooki.

"In 2008, the National Institutes of Health (NIH) announced that $190 million had been earmarked for epigenetics research over the next five years," she said. In announcing the funding, government officials noted that epigenetics had the potential to explain mechanisms of aging, hu
'/>"/>

Contact: Heather Curry
hcurry@acr-arrs.org
703-390-9822
American College of Radiology / American Roentgen Ray Society
Source:Eurekalert

Page: 1 2

Related biology news :

1. UD leads $5.3-million research project on rice epigenetics
2. UD leads $5.3-million research project on rice epigenetics
3. Environmental epigenetics has potential for preventing and treating disease
4. The epigenetics of increasing weight through the generations
5. Ali Shilatifard and colleagues aim to clarify the definition of epigenetics
6. New nucleotide could revolutionize epigenetics
7. New piece found in the puzzle of epigenetics
8. Newly created cancer stem cells could aid breast cancer research
9. Obesity and lack of exercise could enhance the risk of pancreatic cancer
10. Finding that 1-in-a-billion that could lead to disease
11. 60 second test could help early diagnosis of common brain diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/5/2014)... the UTSA College of Sciences, is one of ... a two-year $300,00 National Science Foundation (NSF) Early ... supports President Obama,s BRAIN Initiative, a federal effort ... will demystify complex brain processes. , According ... into the interactions of multiple components, each working ...
(Date:11/4/2014)... Medicine announced today that it is a Grand ... Bill & Melinda Gates Foundation. Laura Goetzl, ... Sciences; and Vice Chair of Research and Academic ... pursue an innovative global health and development research ... Neurodevelopment.", Grand Challenges Explorations (GCE) funds individuals worldwide ...
(Date:11/4/2014)... Nov. 4, 2014   Neurotechnology , a ... that the latest version of its fingerprint matching ... Ongoing MINEX evaluation organized by NIST. The ... using the INCITS 378 fingerprint standard template format. ... public tenders in the United States ...
Breaking Biology News(10 mins):UTSA biology professor awarded $300,000 NSF grant for brain research 2UTSA biology professor awarded $300,000 NSF grant for brain research 3Temple University School of Medicine receives Grand Challenges Explorations grant 2Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 2Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 3
... American Psychiatric Association today released the proposed draft diagnostic ... Manual of Mental Disorders (DSM). The draft ... is the standard classification of mental disorders used by ... for diagnostic and research purposes. "These draft ...
... plants stave off attacks by Hessian fly larvae by essentially ... according to a study by Purdue University and the U.S. ... to human intestines - were observed in three different feeding ... that were given nothing to eat showed no damage to ...
... AMES, Iowa -- A previous six-month study by Iowa ... of soy protein, rich in isoflavones, lessened lumbar spine ... expanded three-year study by some of those same researchers ... who ingested soy isoflavone tablets, except for a modest ...
Cached Biology News:APA announces draft diagnostic criteria for DSM-5 2APA announces draft diagnostic criteria for DSM-5 3APA announces draft diagnostic criteria for DSM-5 4APA announces draft diagnostic criteria for DSM-5 5Resistant wheat goes for the gut to protect against Hessian flies 2Multicenter study finds little effect of soy isoflavones on bone loss in postmenopausal women 2Multicenter study finds little effect of soy isoflavones on bone loss in postmenopausal women 3
(Date:11/24/2014)... November 24, 2014 The new ... from METTLER TOLEDO demonstrates how to reduce the ... analytics and sample panel design can be complicated, ... and protect against corrosion and deposition. Dedicated single ... significant amount of panel space. Additionally, installing and ...
(Date:11/24/2014)... November 24, 2014 Senior Vice ... for dynamic leadership skills, business acumen ... medical information products and services, congratulates Diane Bartoli ... Reference and Workflow, Elsevier Clinical Solutions, for being recognized ... ® Awards issue of Profiles in Diversity ...
(Date:11/22/2014)... 2014 Two new educational webinars hosted by ... for ALS research and how the pharmaceutical industry can make ... Bucket Challenge: Where Does the ALS Money Go? , Featuring ... 2014, Time: 1:30pm ET, Register to attend , ... Merit Cudkowicz, Julianne Dorn Professor of Neurology at Massachusetts General ...
(Date:11/22/2014)... November 21, 2014 Prominent academics, ... will gather on December 3rd at Genetic Rx, ... series. GeneticRx will take place at the Joseph ... and will discuss the present and future of ... skipping, and gene editing—as well as the treatment ...
Breaking Biology Technology:New Video Shows How to Simplify Cycle Chemistry Sample Panels to Save Time and Costs 2Elsevier Clinical Solutions' Diane Bartoli Featured In Profiles in Diversity Journal's 13th Annual Women Worth Watching Issue 2Elsevier Clinical Solutions' Diane Bartoli Featured In Profiles in Diversity Journal's 13th Annual Women Worth Watching Issue 3DrugDev Webinars in December to Explore What Comes Next for ALS Research and How We Can Make Life Easier for Clinical Sites 2Pioneering Academics and Key Industry Leaders to Discuss Rare Diseases and the Emergence of New Genetic Medicines at Genetic Rx on December 3rd 2
... Assembly Speaker Mike Huebsch , R-West Salem, and ... legislators to serve on the Speaker's Task Force on Information ... exploring a number of failed information technology projects in state ... private sectors. , ,In addition to Montgomery, who will serve ...
... year's Biotechnology Industry Organization convention in Chicago, it wasn't ... While Chicago is a business leader in almost every ... its biotech. Pharmaceutical companies, yes; biotech firms, not really. ... so hopped up on biotech research, investors, and boom-time ...
... of healthcare information technology continues its slow but steady march, new ... progress that has been made, and the issues still to address, ... set for May 9 and 10 at the Fluno Center ... Dr. Barry Chaiken Dr. Barry Chaiken, associate chief medical ...
Cached Biology Technology:Eight lawmakers named to Speaker's IT task force 2Getting noticed in Genetown: Wisconsin biotech on display 2Getting noticed in Genetown: Wisconsin biotech on display 3Getting noticed in Genetown: Wisconsin biotech on display 4Digital Healthcare Conference 2007: Mounting obstacles for health IT 2Digital Healthcare Conference 2007: Mounting obstacles for health IT 3