Navigation Links
Enzymes allow DNA to swap information with exotic molecules
Date:3/21/2013

heir information-carrying role, DNA and RNA possess two defining properties: heredity, (which allows them to propagate their genetic sequences to subsequent generations) and evolution, (which allows successive sequences to be modified over time and to respond to selective pressure).

The chemical complexity of DNA has convinced most biologists that it almost certainly did not arise spontaneously from the prebiotic soup existing early in earth's history. According to one hypothesis, the simpler RNA molecule may at one time have held dominion as the sole transmitter of the genetic code. RNA is also capable of acting as an enzyme and may have catalyzed important chemical reactions leading eventually to the first cellular life.

But RNA is still a complex molecule and the search for a simpler precursor that may have acted as a stepping-stone to the RNA, DNA and protein system that exists today has been intense.

A variety of xenonucleic acids are being explored as candidates for the role of transitional molecule. In the current study, threose nucleic acid or TNA is investigated. Chaput says that establishing TNA as a progenitor of RNA would require demonstrating that TNA can perform functions that would help support a pre-RNA world. Of particular importance, would have been the ability replicate itself in the absence of protein enzymes.

Like DNA, TNA can form double-helicesspiral staircase structures consisting of the 4 nucleotide bases, which make up the ladder-like rungs, and a sugar and phosphorus backbone, which forms the ladder's railing. The sugar portion of this backbone is a defining component of the nucleic acid. DNA uses deoxyribose, RNA uses ribose and TNA uses threose.

Both DNA and RNA have sugars containing five carbon atoms, but TNA's threose sugar contains only four. This enables TNA to assemble from just two identical carbon units, making it far easier to form under the non-biological conditions than RNA or
'/>"/>

Contact: Joseph Caspermeyer
Joseph.Caspermeyer@asu.edu
Arizona State University
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. DNA catalysts do the work of protein enzymes
2. Organizing enzymes to create electricity
3. Promiscuous enzymes may be recruited to aid industry, medical fields
4. Powerful enzymes create ethanol from agricultural harvest waste
5. Nutrient-sensing enzymes key to starvation response and survival in newborn mammals
6. Researchers use blood testing to predict level of enzymes that facilitate disease progression
7. New inhibitors of elusive enzymes promise to be valuable scientific tools
8. Ancient enzymes function like nanopistons to unwind RNA
9. Is it a rock, or is it Jell-O? Defining the architecture of rhomboid enzymes
10. ORNL process improves catalytic rate of enzymes by 3,000 percent
11. More accurate, sensitive DNA test allows early identification of fungus causing WNS
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Enzymes allow DNA to swap information with exotic molecules
(Date:1/22/2015)... MELBOURNE, Fla. , Jan. 13, 2015  Today, ... wearable technology, launched its crowdfunding campaign on Fundable, ... accelerate the build of production capacity to meet ... Photo - http://photos.prnewswire.com/prnh/20150113/168790 ...
(Date:1/22/2015)... man-made form of insulin delivered by nasal spray may ... with mild cognitive impairment and Alzheimer,s disease dementia, according ... Forest Baptist Medical Center. The study,s subjects ... (MCI) or mild to moderate Alzheimer,s dementia (AD). Those ...
(Date:1/22/2015)... YORK , Jan. 21, 2015  Analyst Report Issued by ... Card Brands report showed that planet-wide, transactions at merchants on ... while the total number of credit, debit, and prepaid cards ... U.S. were victims of fraudulent card usage in 2012, and ...
Breaking Biology News(10 mins):FreeWavz Launches on Fundable to Drive Speed-to-Market in 2015 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 2Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer's Dementia 3$4.80 Near Term Price Target with "Buy" given by CapRock Research for NXT-ID, Inc. (NASDAQ: NXTD) issued by Small Cap IR 2
... for months after a traumatic brain injury (TBI), revealing ... new research led by the University of Melbourne, Australia ... Neurotrauma Initiative is published in the latest issue of ... Around 400,000 Australians have a disability related to traumatic ...
... PDL BioPharma, Inc. (PDL) (Nasdaq: PDLI ) ... results on Wednesday, November 10, 2010 after the markets close. PDL,s ... Eastern Time to discuss the financial results.   ... call via phone, please dial (866) 271-5140 from the United States ...
... HAGUE (2 November 2010)A unique acacia known as a "fertilizer ... maize yields in smallholder agriculture in Zambia and Malawi, according ... The findings were central to the arguments of agroforestry experts ... technology more widely throughout the African nations most vulnerable to ...
Cached Biology News:Study provides treatment hope for long term effects of brain trauma 2PDL BioPharma to Announce Third Quarter 2010 Financial Results on November 10, 2010 2Scientists find that evergreen agriculture boosts crop yields 2Scientists find that evergreen agriculture boosts crop yields 3
(Date:3/3/2015)... 3, 2015 /CNW/- SQI Diagnostics Inc. (TSX:V: SQD), a life ... and products for advanced microarray diagnostics, today announced ...  to its Management team. In his capacity as ... transition from a development stage to a commercially ... the Company,s capital market strategy and to secure ...
(Date:3/3/2015)... LITTLE FALLS, N.J. , March 3, 2015 /PRNewswire/ ... a biotechnology company specializing in the development of and ... of damaged tissues and organs, announced today that it ... Purchase Agreement with Amarantus Bioscience Holdings, Inc. (OTC Bulletin ... required under the Agreement, Amarantus made the final payments ...
(Date:3/3/2015)... 3, 2015  RegeneRx Biopharmaceuticals, Inc. (OTCQB: RGRX) ("the ... journal, Expert Opinion on Biological Therapy , Dr. ... Zhenggang Zhang , at the Henry Ford Hospital in ... beta 4 (TB4) has the capacity to promote CNS ... more post-injury, leading to neurological recovery in each case.  ...
(Date:3/3/2015)... 3, 2015 Kindred Biosciences, Inc. (NASDAQ: ... the lives of pets, announced today that it will release ... 12, 2015 after the market close. The Company will host ... Interested parties may access the call by ... internationally, and using conference ID 98449349.  The ...
Breaking Biology Technology:SQI Diagnostics Appoints Chief Financial Officer 2SQI Diagnostics Appoints Chief Financial Officer 3Regenicin (RGIN) Receives $2.3 Million in Final Payment from Amarantus 2Regenicin (RGIN) Receives $2.3 Million in Final Payment from Amarantus 3Researchers at Henry Ford Hospital Propose Thymosin Beta 4 as Novel Way to Treat Neural Injury and Neurodegenerative Diseases 2Researchers at Henry Ford Hospital Propose Thymosin Beta 4 as Novel Way to Treat Neural Injury and Neurodegenerative Diseases 3
... May 26 , - Production Increase Brings ... Therapeutics (Euronext: AMT), a leader in the field,of ... a Cooperative,Research and Development Agreement from the National ... Institutes of Health (NIH), Bethesda,Maryland, that promises to ...
... AMLN ) will Web cast its Annual Meeting ... PT from the company,s corporate,headquarters in San Diego, CA. ... Executive Officer of Amylin Pharmaceuticals,will be providing a corporate ... and a recording will be made,available following the event. ...
... - Oncolytics Biotech Inc. (TSX:,ONC, NASDAQ: ONCY) ... Patent 2,360,833 entitled "Reovirus for the Treatment ... use of one or more,recombinant reoviruses to ... provides the Company with additional patent protection ...
Cached Biology Technology:AMT's Cooperative Research and Development Agreement With NIH to Boost Production Capacity 2AMT's Cooperative Research and Development Agreement With NIH to Boost Production Capacity 3Oncolytics Biotech Inc. Announces Issuance of 9th Canadian Patent 2
HES-1 [Hairy 1], Available Summer 2003...
E1A (adenovirus early region 1)...
... 1 ( Abpromise for all tested ... peptide: MAATGANAEK AESHNDCPVR LLNPNIAKMK EDILYHFNLT TSRHNFPALF GDVKFVCVGG ... acids 1-99 of Human Uridine Phosphorylase 1 ... 7378 Swiss Protein ID: ...
Nucleobindin 1 [NUCB1]...
Biology Products: