Navigation Links
Environmental estrogens affect early developmental activity in zebrafish
Date:6/21/2012

MADISON, WI June 21, 2012 Chemicals in the environment that mimic estrogen can strongly influence the development of humans and other animals. New research to be presented at the 2012 International Zebrafish Development and Genetics Conference, held June 20-24 in Madison, Wisconsin, reveals that these substances may act even earlier than previously realized, at the very beginning stages of embryonic development.

Estrogenic compounds in the environment are both naturally occurring, such as in food plants, and synthetic, such as bisphenol A (BPA), used in making hard plastic bottles, like baby bottles and metal-based food and beverage cans, including those for baby formula. They are known to affect development of the sex organs, but not much is known about other effects, including any at beginning embryonic development. "The timing of exposure is critical. Evidence from animals suggests that there are critical periods of development when endocrine disruptors could be more deleterious than exposure during adulthood," says Daniel Gorelick, Ph.D., a postdoctoral fellow at the Carnegie Institution for Science.

Working with Professor Marnie Halpern, Ph.D., Dr. Gorelick discovered a new and unexpected activity of estrogenic compounds during early stages of embryonic development. He will present his findings at the conference on Sunday, June 24.

The researchers used zebrafish, which offer several advantages for studying this question. "People have used fish as environmental sentinels for aquatic pollution for decades," Dr. Gorelick says. Most studies, however, have been limited to fairly crude effects such as death or large-scale changes in single genes.

The researchers took advantage of the genetic tools available for zebrafish to study where and when estrogen receptors are active throughout the body. They genetically developed fish whose cells make a green fluorescent protein when their estrogen receptors are activated and looked
'/>"/>

Contact: Phyllis Edelman
pedelman@genetics-gsa.org
301-351-0896
Genetics Society of America
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Mason environmentalist awarded Blue Planet Prize for lifetime achievement in conservation
2. Reed Elsevier Environmental Challenge shortlists 2012 projects
3. Environmental benefit of biofuels is overestimated, new study reveals
4. Wells Fargo fosters environmental conservation through University of Miamis RJD program
5. Tiny plants could cut costs, shrink environmental footprint
6. New museum-university partnership ushers in new era of environmental science education
7. Long-term research reveals causes and consequences of environmental change
8. Stomata development in plants unraveled -- a valuable discovery for environmental research
9. Increasing water scarcity in Californias Bay-Delta will necessitate trade-offs; hard decisions needed to balance various environmental risks
10. Environmental factors in Tiny Tims near fatal illness
11. Reproductive health providers should discuss environmental exposure risks with patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... Dec. 22, 2014  The 2014 Holiday Season ... industry as Acuity Market Intelligence reports that the ... be open. Acuity forecasts that intensifying demand for ... incorporate biometrics will drive a global market of ... devices by 2020.   According to ...
(Date:12/19/2014)... Dec. 18, 2014 Research and Markets ... "Micro Market Monitor: North America Perimeter Security Systems ... http://photos.prnewswire.com/prnh/20130307/600769 The North American ... CAGR of 3.6% from 2014 to 2019. Although the ... Canada is expected to grow ...
(Date:12/19/2014)... 18, 2014   LaunchKey , the first decentralized ... and Internet of Things era, today announced the close ... round was led by Metamorphic Ventures with participation from ... VegasTechFund, and others.  LaunchKey has raised $4 million to ... its team and bring LaunchKey to market in 2015. ...
Breaking Biology News(10 mins):First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3
... conditions in California could be a gold mine to ... relationships and how these inner workings might apply on ... today on Science Online, researchers from the Department of ... California Berkeley describe a bacterial community that flourishes in ...
... shape the growth of engineered tissueCollagen often pops up ... collagen with a molecular hitchhiker, materials scientists at Johns ... researchers have found a simple new way to modify ... a treatment to block the formation of unwanted scar ...
... the marine bacterium Colwellia psychrerythraea 34H keeps very cool--typically ... in this frigid environment? To find out, scientists at ... sequenced and analyzed C. psychrerythraea's genome. , That genome ... of Sciences (PNAS) Online Early Edition July 25-29, reveals ...
Cached Biology News:ORNL, UC Berkeley unravel real-world clues to Earth's mysteries 2ORNL, UC Berkeley unravel real-world clues to Earth's mysteries 3Modified collagen could yield important medical applications 2Modified collagen could yield important medical applications 3Deep thinking: Scientists sequence a cold-loving marine microbe 2Deep thinking: Scientists sequence a cold-loving marine microbe 3
(Date:12/24/2014)... , Dec. 23, 2014 Sigma-Aldrich Corporation ... the waiting period under the Hart-Scott-Rodino Antitrust Improvements ... expired on December 22, 2014, thereby completing the ... for the acquisition of the Company by Merck ... clearance satisfies another condition to closing the transaction, ...
(Date:12/22/2014)... Md. , Dec. 22, 2014 /PRNewswire/ ... SYN), a developer of pathogen-specific therapies for ... on protecting the microbiome, today announced positive ... Phase 1a clinical trial of SYN-004, the ... prevention of Clostridium difficile (C. difficile) ...
(Date:12/22/2014)... 22, 2014  ( www.competitivehealth.com ) — Competitive Health ... bill review and advocacy service, has signed an agreement ... Savings discount health services marketplace. 63% of ... than they expected to pay. As part of an ... WellCard Savings is pleased to offer medical bill review ...
(Date:12/19/2014)... December 19, 2014 Bioject Medical ... and manufacturer of needle-free injection technology, today announced ... Immunomic Therapeutics, Inc. (“ITI”) for ITI to use ... its LAMP™ vaccine platform. , In the ... Worldwide license to the Biojector®-2000 that triggers based ...
Breaking Biology Technology:Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 2Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 2Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 4Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 5WellCard Savings Announces CoPatient Medical Bill Review Service for Members 2Bioject and Immunomic Therapeutics Enter into an Agreement for License of Needle-Free Technology for LAMP-vax Vaccines 2Bioject and Immunomic Therapeutics Enter into an Agreement for License of Needle-Free Technology for LAMP-vax Vaccines 3
... economic development in Dane County, Madison Gas & ... last 20 years as it works to nurture entrepreneurial ... tomorrow's major league employers. , ,For MG&E, it's part ... creating the right conditions for entrepreneurs by providing financial ...
... completed its previously announced acquisition of MARC Global Holdings, ... to 738 employees at 21 sites with $172 million ... MARC. , ,Former MARC CEO Oliver Cooper will have ... company leader John Jazwiec. , ,"The integration of MARC ...
... are pushing state restrictions on human embryonic stem ... beyond President Bush's 2001 order and put Wisconsin's ... ,Rather than adding a layer of unnecessary regulation, ... -- one federal and the other international -- ...
Cached Biology Technology:How MG&E bets on small companies for the long term 2How MG&E bets on small companies for the long term 3How MG&E bets on small companies for the long term 4Federal and global guidelines on stem cell research offer a level playing field 2Federal and global guidelines on stem cell research offer a level playing field 3