LA JOLLA, CA, October 21, 2010 A multi-institutional consortium led by The Scripps Research Institute scientists, the Joint Center for Structural Genomics (JCSG), is the sole focus of a special issue of the journal Acta Crystallographica Section F. This is the first time in the history of the monthly journal, which publishes peer-reviewed crystallography and structural biology articles, that an entire issue is devoted to the works of a single scientific center.
The issue contains 35 articles grouped into sections that highlight different aspects of the JCSG high-throughput structural biology pipeline. Context and independent analysis for the specific topics and groups of JCSG papers is provided by overviews written by a well-known expert in the field. The JCSG special issue can be found at http://journals.iucr.org/f/issues/2010/10/00/issconts.html.
"This special issue marks a milestone for the journal and possibly for the JCSG," says Manfred Weiss, section editor of Acta Crystallographica F and a scientist at Helmholtz-Zentrum in Berlin. "Since the advent of structural genomics, there has been a publication bottleneck, and with now over 5,000 structures solved from the National Institutes of Health (NIH) Protein Structure Initiative (PSI) alone, this problem is becoming ever more serious. This special issue is an attempt to help solve this publication problem."
The JCSG, which conducts research to describe the three-dimensional structures of proteins, is led by Ian A. Wilson, who is Hansen Professor of Structural Biology and member of the Skaggs Institute for Chemical Biology at Scripps Research. Wilson explains that the center was formed after a series of informal and formal meetings in 1999 with Scripps Research investigators and other leading scientists in the field who saw a need to spearhead efforts to explore and develop high-throughput structural
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Scripps Research Institute