Navigation Links
Engineers study brain folding in higher mammals
Date:10/1/2007

Engineers at Washington University in St. Louis are finding common ground between the shaping of the brain and the heart during embryonic development.

Larry A.Taber, Ph.D., the Dennis and Barbara Kessler Professor of Biomedical Engineering, and Phillip Bayly, Ph.D., Hughes Professor of Mechanical Engineering, are examining mechanical and developmental processes that occur in the folding of the brains surface, or cortex, which gives the higher mammalian brain more surface area (and hence more intellectual capacity) than a brain of comparable volume with a smooth surface.

Folding is very important in human brain development because some of the worst neurological problems such as schizophrenia, autism and lissenchephaly (smoothness of the cortex, found with severe retardation) are associated with abnormal brain folding. The neuromuscular disorder dystonia is possibly associated with faulty connectivity in the brain, which has been hypothesized to affect cortical folding. The researchers hope that increased understanding of brain folding might someday help prevent such diseases.

Although folding is generally what makes higher mammals smart, Albert Einstein had an abnormally folded brain that resulted in genius. Certain folds in his brain were absent, which might have enabled the area associated with mathematical reasoning to be larger than normal because it didnt have a boundary to restrict its growth.

Looping, folding

According to Taber, the heart and the brain both begin as simple tubes that eventually develop in totally different ways. Looping is a key phenomenon in the early embryo where the tubular heart bends and rotates in a precise manner. Taber has found that the processes of bending and rotation in the embryonic heart are actually driven by at least two different mechanical forces. His research could help scientists better understand the roles physics and mechanics play in the normal developing heart
'/>"/>

Contact: Tony Fitzpatrick
tony_fitzpatrick@wustl.edu
314-935-5272
Washington University in St. Louis
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Duke engineers develop new 3-D cardiac imaging probe
2. Engineers improve plastics potential for use in implants by linking it to biological material
3. MIT engineers an anti-cancer smart bomb
4. Scientists and engineers apply natures design to human problems
5. Engineers discover why toucan beaks are models of lightweight strength
6. Bioengineers create stable networks of blood vessels
7. Rice bioengineers pioneer techniques for knee repair
8. UW-Madison engineers squeeze secrets from proteins
9. MIT engineers probe spiders polymer art
10. Boston University biomedical engineers win major grant for pursuit of the $1,000 Genome
11. Bioartificial kidney under study at MCG
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... showed that mutations in prickle genes cause epilepsy, ... by repeated seizures over time. However, the mechanism ... A new University of Iowa study, published online ... National Academy of Sciences , reveals a novel ... have identified the basic cellular mechanism that goes ...
(Date:7/22/2014)... research in the Journal of Clinical ... signaling and dopamine transporter function are linked ... Parkinsonism and attention deficit hyperactivity disorder (ADHD). ... critical basis for further exploration of how ... contribute to brain disorders" said Michelle Sahai, ...
(Date:7/22/2014)... on July 14, 2014, by lightning from a weather system ... of four fires: Stokes Fire, Gold Hikes Fire, French Creek ... fires are now one larger fire. The fires are burning ... over 243,000 acres in size. The present fire situation ... Public and firefighter safety is the priority on the Carlton ...
Breaking Biology News(10 mins):UI study finds potential genetic link between epilepsy and neurodegenerative disorders 2The dopamine transporter 2The dopamine transporter 3
... from early hominid to dominant species, is the defining ... To chronicle this epic narrative an internationally renowned team, ... University, presents the Wiley-Blackwell Encyclopedia of Human Evolution, a ... history. Over two volumes and 5000 entries ...
... Boston, MA - Some 25 million people in the United ... diseases characterized by often debilitating pain in the joints. Now ... gel that could spell the future for treating these diseases ... the targeted release of medicine at an affected joint, and ...
... crustaceans called copepods rule the world, at least when ... numerous multi-cellular organisms in the seas, copepods are an ... webs. To understand and predict how copepods respond ... how many new copepods are born, but how many ...
Cached Biology News:Injectable gel could spell relief for arthritis sufferers 2Injectable gel could spell relief for arthritis sufferers 3Death -- not just life -- important link in marine ecosystems 2
(Date:7/21/2014)... 2014 Lawrence Livermore National ... (WIB) and Las Positas College (LPC) recently established ... and hands-on training for veterans, officials recently announced. ... Las Positas is designed to help veterans ... technician careers, and establishes a pipeline of qualified ...
(Date:7/21/2014)... a chain of carbon atoms can turn it from ... University scientists. , Stretching the material known as carbyne ... by just 3 percent can begin to change its ... mechanically activated nanoscale electronics and optics. , The finding ... appears in the American Chemical Society journal Nano ...
(Date:7/21/2014)... EUGENE, Ore. (July 21, 2014) The yield ... of Oregon have developed a low-energy, solution-based mineral substitution ... that could find use in electronics and alternative energy ... on the cover of the July 21 issue of ... most citations of research in the inorganic and nuclear ...
(Date:7/21/2014)... York , July 21, 2014 ... on Global & USA ... Trends, and Forecasts ResearchMoz presents this ... Biomaker Market   to 2018 (Identification, Technologies, Market Analysis, ... Trends, and Pipeline Analysis. GLOBAL & ...
Breaking Biology Technology:Engineering Program Established for Veterans 2Engineering Program Established for Veterans 3Carbyne morphs when stretched 2Carbyne morphs when stretched 3Oregon chemists eye improved thin films with metal substitution 2Global & USA Cancer Biomaker Market to 2018 (Identification, Technologies, Market Analysis, Competitor Profiles, Companion Diagnostic Co-Development, Business Strategies, Industry Trends, and Pipeline Analysis) - Market Size, Trends, and Forecasts A 2Global & USA Cancer Biomaker Market to 2018 (Identification, Technologies, Market Analysis, Competitor Profiles, Companion Diagnostic Co-Development, Business Strategies, Industry Trends, and Pipeline Analysis) - Market Size, Trends, and Forecasts A 3Global & USA Cancer Biomaker Market to 2018 (Identification, Technologies, Market Analysis, Competitor Profiles, Companion Diagnostic Co-Development, Business Strategies, Industry Trends, and Pipeline Analysis) - Market Size, Trends, and Forecasts A 4Global & USA Cancer Biomaker Market to 2018 (Identification, Technologies, Market Analysis, Competitor Profiles, Companion Diagnostic Co-Development, Business Strategies, Industry Trends, and Pipeline Analysis) - Market Size, Trends, and Forecasts A 5Global & USA Cancer Biomaker Market to 2018 (Identification, Technologies, Market Analysis, Competitor Profiles, Companion Diagnostic Co-Development, Business Strategies, Industry Trends, and Pipeline Analysis) - Market Size, Trends, and Forecasts A 6
... Oncology Biomarkers, FREMONT, Calif., Feb. 6 ... high-value molecular diagnostics company, today announced,the renewal ... University,on the development of novel biomarkers that ... monitoring of prevalent cancers, including,ovarian, breast and ...
... BRL ) today announced that its subsidiary, Barr ... Co., Inc.,s Fosamax(R),(Alendronate Sodium) Tablets, 70 mg after receiving ... The FDA approved the Company,s application on February ... the,earliest to expire of the patents listed with the ...
... 6 Iomai Corporation,(Nasdaq: IOMI ) today announced ... officer, will present at the 10th Annual BIO,CEO & ... 12. Mr. Erck,s,presentation will begin at 2 p.m. Eastern ... Mr. Erck will give an update on corporate ...
Cached Biology Technology:Vermillion and Johns Hopkins Sign Collaborative Research and License Agreements to Develop Molecular Diagnostic Tests 2Barr Launches Generic Fosamax(R) Tablets, 70 mg 2Barr Launches Generic Fosamax(R) Tablets, 70 mg 3Barr Launches Generic Fosamax(R) Tablets, 70 mg 4Iomai CEO to Speak at BIO CEO & Investor Forum on Feb. 12 2
... Schistosomal glutathione-S-transferase (GST) is commonly used ... in E. coli (1). The GSTTag sequence ... and in some cases the solubility of ... soluble, properly folded form, GSTTag fusion proteins ...
... your samples with eArray and Agilents custom printing. ... own microarray designs that meet your specific biological ... delivery of your arrays in weeks, anywhere in ... creation application tool that enables you to design ...
Acetylcholinesterase (human brain, AChE)...
... 7500ce meets the demands of the routine ... performance from reliable, robust and simple to ... power in the most challenging sample matrices ... equally suited to the toughest analytical challenges ...
Biology Products: