Navigation Links
Engineers demonstrate a new type of optical tweezer

CAMBRIDGE, Mass. -- February 25, 2008 -- Researchers at the Harvard School of Engineering and Applied Sciences (SEAS) demonstrated a new type of optical tweezer with the potential to make biological and microfluidic force measurements in integrated systems such as microfluidic chips. The tweezer, consisting of a Fresnel Zone Plate microfabricated on a glass slide, has the ability to trap particles without the need for high performance objective lenses.

The device was designed, fabricated, and tested by postdoctoral fellow Ethan Schonbrun and undergraduate researcher Charles Rinzler under the direction of Assistant Professor of Electrical Engineering Ken Crozier (all are affiliated with SEAS). The team's results were published in the February 18th edition of Applied Physics Letters and the researchers have filed a U.S. provisional patent covering this new device.

"The microfabricated nature of the new optical tweezer offers an important advantage over conventional optical tweezers based on microscope objective lenses," says Crozier. "High performance objective lenses usually have very short working distances -- the trap is often ~200 mm or less from the front surface of the lens. This prevents their use in many microfluidic chips since these frequently have glass walls that are thicker than this."

The researchers note that the Fresnel Zone Plate optical tweezers could be fabricated on the inner walls of microfluidic channels or even inside cylindrical or spherical chambers and could perform calibrated force measurements in a footprint of only 100x100┬Ám.

Traditional tweezers, by contrast, would suffer from crippling aberrations in such locations. Moreover, in experimental trials, the optical tweezers exhibited trapping performance comparable to conventional optical tweezers when the diffraction efficiency was taken into account.

The researchers envision using their new tweezer inside microfluidic chips to carry out fluid velocity, refractive index, and local viscosity measurements. Additional applications include biological force measurements and sorting particles based on their size and refractive index. Particle-sorting chips based on large arrays of tweezers could be used to extract the components of interest of a biological sample in a high-throughput manner.


Contact: Michael Patrick Rutter
Harvard University

Related biology news :

1. Where will we find the next generation of engineers?
2. Birds, bats and insects hold secrets for aerospace engineers
3. Elephant engineers
4. Penn engineers create carbon nanopipettes that are smaller than cells and measure electric current
5. President honors mentors of scientists and engineers
6. Nanoengineers mine tiny diamonds for drug delivery
7. Engineers study brain folding in higher mammals
8. Institution of Chemical Engineers chooses Elsevier as publishing partner
9. CU researcher engineers sorghum that grows in poisonous soils
10. Boston University biomedical engineers find chink in bacterias armor
11. UCR engineers to develop new tool to measure how environmental exposures affect health
Post Your Comments:
Related Image:
Engineers demonstrate a new type of optical tweezer
(Date:11/30/2015)... Nov. 30, 2015  BIOCLAIM announced today that ... year,s Fierce Innovation Awards:  Healthcare Edition, an awards ... , FierceHealthcare , and ... finalist in the category of "Privacy and Cybersecurity." ... --> Photo - ...
(Date:11/26/2015)... Nov. 26, 2015 Research and Markets ( ... "Capacitive Fingerprint Sensors - Technology and Patent Infringement Risk ... --> --> Fingerprint sensors using ... smartphones. The fingerprint sensor vendor Idex forecasts an increase ... in mobile devices and of the fingerprint sensor market ...
(Date:11/20/2015)... NXTD ) ("NXT-ID" or the ... mobile commerce market and creator of the Wocket® smart ... recently interviewed on The RedChip Money Report ... on Bloomberg Europe , Bloomberg Asia, Bloomberg Australia, ... NXTD ) ("NXT-ID" or the "Company"), a biometric authentication ...
Breaking Biology News(10 mins):
(Date:11/30/2015)... ... ... Global Stem Cells Group announced that its scientific team is in ... stem cells. The announcement starts a new phase toward launching the simple, quick system ... the lipoaspirate obtained from liposuction of excess adipose tissue. , Lipoaspirate, contains a ...
(Date:11/30/2015)... Dec. 1, 2015 /PRNewswire/ - BioAmber Inc. (NYSE: BIOA ), ... joined the American Business Act on Climate Pledge, alongside more ... standing with the Obama Administration to demonstrate an ongoing commitment ... outcome to the COP21 Paris climate ... Sarnia, Canada . --> BioAmber ...
(Date:11/30/2015)... , Nov. 30, 2015 /PRNewswire/ - Zenith Epigenetics Corp. ... Dr. Norman C.W. Wong to its Board of ... comes to Zenith with a wealth of experience as co-founder ... molecular biology. --> --> ... Zenith Epigenetics, board of directors. Zenith,s long standing expertise in ...
(Date:11/30/2015)... Human Longevity, Inc. (HLI), the genomics-based, technology-driven ... Genomics, Inc., a leading genome informatics company offering highly ... The San Diego -based company has ... and Co-founder, Ashley Van Zeeland , Ph.D., who is ... of the deal were not disclosed. ...
Breaking Biology Technology: