Navigation Links
Engineering a better hip implant
Date:9/18/2012

University of Iowa researchers have determined that thigh size in obese people is a reason their hip implants are more likely to fail.

In a study, the team simulated hip dislocations as they occur in humans and determined that increased thigh girth creates hip instability in morbidly obese patients (those with a body mass index (BMI) greater than 40). The researchers propose that surgeons modify surgical procedures to minimize the chance of dislocation in obese patients and consider other designs for hip replacement implants.

"We have shown that morbidly obese patients' thighs are so large that they are actually pushing each other outward and forcing the implant out of its socket," says Jacob Elkins, a UI graduate student and first author of the paper published in the journal Clinical Orthopaedics and Related Research. "Studies have shown up to a 6.9-fold higher dislocation rate for morbidly obese patients compared to normal weight patients.

Total hip replacement gives mobility back to people who experience debilitating hip joint pain. According to the National Institute of Arthritis and Musculoskeletal and Skin Disease (NIAMS), 231,000 total hip replacements are performed annually in the U.S. and more than 90 percent of these do not require follow-up repair or replacement. But when an implant fails, it is painful, and costly. Studies have shown that dislocation ranks as the most common reason for failed implants, according to Medicare hospital discharge data.

A hip implant is a ball-in-socket mechanism, designed to simulate a human hip joint. However, it lacks the connective tissue that stabilizes a normal hip joint, meaning the ball portion of the implant can sometimes "pop out."

Clinical studies point to an increased dislocation risk among obese patients with total hip replacements, but the reasons have remained unclear. Dislocation requires extreme range of motion, such as flexing at the waist. Given t
'/>"/>

Contact: Richard Lewis
richard-c-lewis@uiowa.edu
319-384-0012
University of Iowa
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UA engineering professor Shane Snyder to speak in Korea on international water quality
2. Engineering research centers awarded $55.5 million to innovate in nanoscale science and engineering
3. £30 million boost for biomedical engineering research
4. University of Minnesota engineering researchers discover new non-invasive method for diagnosing epilepsy
5. UA engineering professor uses aerospace materials to build endless pipeline
6. Genetic Engineering & Biotechnology News unveils Biotech Boulevard
7. Engineering technology reveals eating habits of giant dinosaurs
8. GEN reports on growth of tissue engineering revenues
9. Oligonucleotide Delivery: Biology, Engineering and Development Conference
10. Investigation of American Oriental Bioengineering, Inc. by Securities Lawyers at Goldfarb LLP Law Firm for Potential Shareholder Claim
11. NSF report detailing growth in graduate enrollment in science & engineering in the past decade
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/20/2015)... 19, 2015 Research and Markets ( http://www.researchandmarkets.com/research/rswjb4/hand_geometry ... - Global Strategic Business Report" report to their offering. ... Geometry in US$ Thousands. The report provides separate comprehensive analytics ... Japan , Europe , ... Rest of World. Annual estimates and forecasts are ...
(Date:3/17/2015)... 2015 MedNet Solutions , a ... study management systems, is pleased to announce that ... Outsourcing in Clinical Trials Southeast conference – March ... excellent forum for MedNet to showcase iMedNet ... (SaaS) eClinical technology platform. We strongly ...
(Date:3/12/2015)... March 12, 2015 The mascots of the ... Hospital, part of Wake Forest Baptist Medical Center. They ... the 2015 ACC Men,s Basketball Tournament. Young patients enjoyed ... and getting their autographs. Brenner Children,s Hospital ... is the only children,s hospital in northwest ...
Breaking Biology News(10 mins):Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 2Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 4Connect With MedNet Solutions At Outsourcing In Clinical Trials Southeast 2
... 2010 UT Southwestern Medical Center researchers have found new ... susceptible to stress than others. In a study of ... event, animals that were more susceptible to stress exhibited enhanced ... brain. Specifically, the cells that these animals produced after a ...
... Hemophilia, a disease linked with legends of European monarchs, frail ... people today. And the very treatments that can help ... treatment is infusion with an expensively produced protein that helps ... system fights the therapy, and in a subset of those, ...
... N.J. ―The Center for Secure and Resilient Maritime Commerce (CSR) ... report. Stevens was named by the US Department ... Centers of Excellence and was selected to lead a national ... 11 universities to partner with the DHS and serve as ...
Cached Biology News:New brain nerve cells key to stress resilience, UT Southwestern researchers find 2New brain nerve cells key to stress resilience, UT Southwestern researchers find 3Researchers harness the power of plants to fight hemophilia 2Researchers harness the power of plants to fight hemophilia 3Researchers harness the power of plants to fight hemophilia 4
(Date:3/30/2015)... 30, 2015 CASI Pharmaceuticals, Inc. (Nasdaq: ... development and commercialization of innovative therapeutics addressing cancer and ... a commercial focus on China , ... (CFDA) has approved the Company,s application to conduct a ... carcinoma (OCCC) patients for its proprietary drug candidate ENMD-2076.  ...
(Date:3/30/2015)... 2015  Spherix Incorporated (Nasdaq: SPEX ) -- an ... and monetization of intellectual property, today provided an ... and  Spherix v. Uniden , Case No. 3:13-cv-03496-M, ... the Northern District of Texas ... Verizon, Case No. 1:14-cv-00721-GBL-TCB, in the United ...
(Date:3/30/2015)... March 30, 2015  Naldemedine, an investigational peripherally ... Shionogi & Co., Ltd., met its primary and ... I) for the treatment of opioid-induced constipation (OIC) ... opioid therapy. Study results showed that naldemedine (0.2 ... the frequency of spontaneous bowel movement (SBM) compared ...
(Date:3/29/2015)... 2015  Caris Life Sciences® today announced the ... Intelligence®, the company,s panomic, comprehensive tumor profiling service, ... rare and difficult to treat gynecological cancers may ... to improve patient outcomes. These studies were presented ... of Gynecologic Oncology (SGO) 2015 Annual Meeting on ...
Breaking Biology Technology:CASI Pharmaceuticals Receives Approval From CFDA For Phase 2 Clinical Trial In China With ENMD-2076 For Ovarian Clear Cell Carcinoma 2CASI Pharmaceuticals Receives Approval From CFDA For Phase 2 Clinical Trial In China With ENMD-2076 For Ovarian Clear Cell Carcinoma 3CASI Pharmaceuticals Receives Approval From CFDA For Phase 2 Clinical Trial In China With ENMD-2076 For Ovarian Clear Cell Carcinoma 4CASI Pharmaceuticals Receives Approval From CFDA For Phase 2 Clinical Trial In China With ENMD-2076 For Ovarian Clear Cell Carcinoma 5Spherix Provides Update on Litigation vs. VTech, Uniden and Verizon 2Spherix Provides Update on Litigation vs. VTech, Uniden and Verizon 3Shionogi & Co., Ltd. Announces That Naldemedine Meets Primary Endpoint In A Phase 3 Study For The Treatment Of Opioid-Induced Constipation 2Shionogi & Co., Ltd. Announces That Naldemedine Meets Primary Endpoint In A Phase 3 Study For The Treatment Of Opioid-Induced Constipation 3Caris Molecular Intelligence Facilitates Comparison of Biomarker Profiles to Inform Targeted Treatment Strategies in Distinct Gynecological Cancers 2Caris Molecular Intelligence Facilitates Comparison of Biomarker Profiles to Inform Targeted Treatment Strategies in Distinct Gynecological Cancers 3Caris Molecular Intelligence Facilitates Comparison of Biomarker Profiles to Inform Targeted Treatment Strategies in Distinct Gynecological Cancers 4
... VILLAGE, Nev., June 8 PDL BioPharma, Inc. (PDL) (Nasdaq: ... second quarter ended June 30, 2009 of approximately $125 million, ... 2008. The increase is due primarily to royalty revenues driven ... marketed by Genentech, and sales of Tysabri(R), which is marketed ...
... reductions in fasting plasma glucose, HbA1c and body weight ... 8 Intarcia Therapeutics, Inc. today presented results from ... delivery of exenatide) for the treatment of type 2 ... the American Diabetes Association in New Orleans, LA (June ...
... N.J., June 8 Celator Pharmaceuticals today announced ... extended therapeutic bioavailability and tumor cell selectivity of ... at the 14th Congress of the European Hematology ... (Abstracts 1398 and 383). , , "These ...
Cached Biology Technology:PDL BioPharma Provides Second Quarter 2009 Revenue Guidance of Approximately $125 Million 2PDL BioPharma Provides Second Quarter 2009 Revenue Guidance of Approximately $125 Million 3Intarcia Therapeutics, Inc. Presents ITCA 650 Phase 1b Study Results as a Late-Breaker at the American Diabetes Association 69th Scientific Sessions 2Intarcia Therapeutics, Inc. Presents ITCA 650 Phase 1b Study Results as a Late-Breaker at the American Diabetes Association 69th Scientific Sessions 3Intarcia Therapeutics, Inc. Presents ITCA 650 Phase 1b Study Results as a Late-Breaker at the American Diabetes Association 69th Scientific Sessions 4Celator(R) Pharmaceuticals Presents Data on the Activity of CPX-351 Against Leukemia at the European Hematology Association Congress 2Celator(R) Pharmaceuticals Presents Data on the Activity of CPX-351 Against Leukemia at the European Hematology Association Congress 3
5 minutes from gel band to purified DNA...
Enables rapid purification of double-stranded DNA fragments = 200 bp, including, for example, PCR reaction products, DNA fragments obtained in restriction enzyme digests, or double-stranded cDNA...
DTT, 25g...
AgarPlaque Plus Agarose 50 grams...
Biology Products: