Navigation Links
Engineer develops detergent to promote peripheral nerve healing
Date:6/10/2008

afts are able to bridge long nerve gaps, provide a three-dimensional pathway supporting nerve regeneration and are easily bendable because they are human nerve harvested from tissue donors, making it easier for surgeons to handle.

"This method has broader applicability," Schmidt says. "Formerly a patient's only option was to use their own nerve or the completely synthetic grafts."

By using the detergent solution, the donor nerve is stripped of the cellular lipid components, which causes the immune rejection response when implanted. Schmidt's laboratory spent four years developing the solution to be strong enough to remove rejection-inducing factors, but mild enough to preserve the delicate physical architecture of the nerve essential for regeneration. The resulting tolerated transplanted nerve provides a type of scaffolding that serves as a bridge between the two ends of the severed nerve to promote regrowth. And because the immunogenic lipid components have been extracted, patients don't require immunosuppressant drugs.

AxoGen learned about the detergent processing work in Schmidt's lab, licensed it and combined it with the University of Florida enzyme treatment that removes other regrowth inhibiting factors, creating the AVANCE product.

"So they've taken something from our lab that works really well and made it work even better," Schmidt says.

Schmidt now is conducting spinal-cord lab testing in animals using detergent-treated peripheral nerve grafts. She is working with post-doctoral fellow Zin Khaing, a central nervous system expert.


'/>"/>

Contact: Christine Schmidt
schmidt@che.utexas.edu
512-471-1690
University of Texas at Austin
Source:Eurekalert

Page: 1 2

Related biology news :

1. bioMETRX Expands Engineering and Manufacturing Capabilities
2. IEEE Fellow first woman to receive highest award in engineering profession
3. NJIT Provost Priscilla P. Nelson honored at National Academy of Engineering
4. Engineer to spearhead research into cell metabolism and medical injuries
5. Prof. David Kisailus studies engineering and invention on the half-shell
6. McMaster University engineering professor receives Humboldt Research Award
7. Genetic Engineering & Biotechnology News reports on growing use of cell-based assays
8. Genetic Engineering & Biotechnology News reports on cancer biomarkers
9. Brown hosts regional bioengineering conference
10. Scientists find that squid beak is both hard and soft, a material that engineers want to copy
11. Small desert beetle found to engineer ecosystems
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2015)... 23, 2015   HOYOS Labs , a leading ... announced that the Company will demonstrate multiple biometrics-based technologies ... consumers at Connect:ID on March 23 through 25, 2015, ... will highlight the IEEE Biometric Open Protocol Standard; free ... enterprise access control system. BOPS was invented by HOYOS ...
(Date:3/20/2015)... and Markets ( http://www.researchandmarkets.com/research/rswjb4/hand_geometry ) has announced the ... Report" report to their offering. This report ... The report provides separate comprehensive analytics for the US, ... Europe , Asia-Pacific , ... Annual estimates and forecasts are provided for the period ...
(Date:3/18/2015)... -- As mobile payments become more prevalent amongst ... apps continue to be introduced into the market place at ... industry in focus today are:  NXT-ID, Inc. (NASDAQ: ... ), Apple Inc. (NASDAQ: AAPL ), Google Inc. ... FB ) NXT-ID, Inc. (NASDAQ: ...
Breaking Biology News(10 mins):HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 2Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 4Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 2Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 3Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 4Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 5Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 6
... Amid the steady drumbeat from nutrition experts and others ... fruits and vegetables there often is a bias to ... is fresh always best? Not necessarily. Dr. Cathy Kapica, ... Wendy Weiss, MA, RD, both with Ketchum Global Health and ...
... from college, the U.S. corn belt could be forced to ... brought on by rising global temperatures. If farmers don,t move ... to bigger swings in corn prices "price volatility" ... price livestock farmers and ethanol producers pay for corn. ...
... and taxation on products containing salt in 19 developing countries ... disease (CVD) by 2-3 per cent in these countries. The ... are the first findings from a new report from Harvard ... The study set out to assess the cost-effectiveness of two ...
Cached Biology News:Obtaining key nutrients from canned foods can save consumers money 2Climate change may create price volatility in the corn market, say Stanford and Purdue researchers 2Tax on salt could reduce cardiovascular disease deaths by 3 percent 2
(Date:4/16/2015)... (PRWEB) April 16, 2015 Capillus, ... distribution and physician network in Europe and Asia. ... has appointed Fernando Bermúdez, former Business Development Director ... An industry veteran, Mr. Bermúdez’s professional achievements include ... in Spain, while also penetrating the Portuguese marketplace ...
(Date:4/16/2015)... Morton Grove, IL (PRWEB) April 16, 2015 ... the American Association for Cancer Research (AACR) ... at the Pennsylvania Convention Center, starting Saturday, April 18, ... The AACR holds claim to title of the oldest ... several journals, provides fellowships and grants, and partners with ...
(Date:4/16/2015)... 16, 2015 The Council for ... prestigious 2015 Borlaug CAST Communication Award goes to ... Tuskegee University in Alabama. Award nominees must demonstrate ... presentations; and/or the use of television, radio, or ... areas. As a specialist in the field of ...
(Date:4/16/2015)... Md. , April 16, 2015  RegeneRx ... today announced its U.S. joint venture with G-treeBNT ... a phase 3 clinical trial for the orphan ... confirmatory trial for dry eye syndrome (DES) in ... preservative-free eye drops, RGN-259/GBT201, this year.  Each of ...
Breaking Biology Technology:Capillus, LLC Extends Laser Hair Therapy Products to Europe and Asia 2Regis Technologies Joins American Association for Cancer Research Annual Meeting 2The 2015 Borlaug CAST Communication Award Goes to Channapatna Prakash 2RegeneRx JV Retains Ora, Inc. to Conduct Phase 3 Trial for NK and Phase 2b/3 Trial for Dry Eye Syndrome in U.S. 2RegeneRx JV Retains Ora, Inc. to Conduct Phase 3 Trial for NK and Phase 2b/3 Trial for Dry Eye Syndrome in U.S. 3RegeneRx JV Retains Ora, Inc. to Conduct Phase 3 Trial for NK and Phase 2b/3 Trial for Dry Eye Syndrome in U.S. 4RegeneRx JV Retains Ora, Inc. to Conduct Phase 3 Trial for NK and Phase 2b/3 Trial for Dry Eye Syndrome in U.S. 5
... Synvista Therapeutics,Inc. (AMEX: SYI ) announced today ... Officer will be featured in an exclusive,interview with ... a.m. EDT. Dr. Berkowitz will discuss the ... in cardiovascular diseases, and alagebrium in,heart failure and ...
... Antibodies and IL-2,Protected 80% of Animals From a Lethal Challenge With a Highly Aggressive,Form of ... ... Targeted, Therapies in Oncology Further Supports a Second Mechanism of Action for ... Anti-PS Antibodies - MANDELIEU, ...
... (OTC Bulletin Board: VQPH), a New Jersey-based,biopharmaceutical company ... announced today that it will,present at the BIO ... p.m.,Pacific Time at the Palace Hotel in the ... president and CEO, is scheduled to give an,overview ...
Cached Biology Technology:Synvista Therapeutics to be Featured on Wallst.net 2New Data Presented on Immunocytokine Fusion Protein Further Supports Broad Anti-Cancer Potential Of Peregrine's Anti-PS Technology Platform 2New Data Presented on Immunocytokine Fusion Protein Further Supports Broad Anti-Cancer Potential Of Peregrine's Anti-PS Technology Platform 3New Data Presented on Immunocytokine Fusion Protein Further Supports Broad Anti-Cancer Potential Of Peregrine's Anti-PS Technology Platform 4VioQuest Pharmaceuticals to Present at BIO InvestorForum in San Francisco 2VioQuest Pharmaceuticals to Present at BIO InvestorForum in San Francisco 3
... Rabbit polyclonal antibody to human XAB2 (amino ... first identified through its interaction with XPA. ... fraction of XAB2 interacts with the transcription-coupled ... as with RNA polymerase II. Microinjection experiments ...
... The Bio-Plex maintenance, calibration, ... is a custom 96-well plate ... validation, and calibration procedures using ... This MCV plate is for ...
... Kits are based on well-established periodate ... consistent and reproducible. This kit contains ... protein or antibody, including ready-to-use buffers ... Activated HRP is supplied ready-to-use and ...
... can be used to label ... covalently bound acridinium NHS ester ... presence of hydrogen peroxide. Acridinium ... used as a detection method ...
Biology Products: