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Embargoed news from Annals of Internal Medicine
Date:9/6/2010

rovide a clearer understanding of what these types of procedures can and cannot do.

3. Radiation-free MRA Provides Accurate Diagnosis of Peripheral Arterial Disease in the Lower Extremities

Lower extremity peripheral arterial disease, or PAD, affects about 10 percent of adults older than 60. An accurate diagnosis is important because PAD increases risk for coronary artery disease, heart attack, stroke, and mini stroke. However, common diagnostic tests such as CTA and DSA are radiation-based. Researchers sought to determine how well radiation-free contrast-enhanced magnetic resonance angiography (MRA) identifies or excludes arterial steno-occlusions in adults with PAD symptoms. The researchers reviewed 32 studies that compared MRA with intra-arterial digital subtraction angiography. They found that contrast-enhanced MRA has both a high sensitivity (about 94.7 percent) for identifying and a high specificity (about 95.6 percent) for excluding arterial steno-occlusions in adults with PAD symptoms. The researchers conclude that MRA is an important diagnostic alternative to CTA and DSA.


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Contact: Angela Collom
acollom@acponline.org
215-351-2653
American College of Physicians
Source:Eurekalert

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