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Elasticity found to stretch stem cell growth to higher levels
Date:10/3/2010

any stem cells as the current hormone-based methods. But the combination of the two produced a super effect with the researchers finding they could create two or three times the number of stem cells than using standard methods on their own.

Professor Tony Weiss^ is a co-author of the Nature Biotechnology paper, and Professor of Biochemistry and Molecular Biotechnology at the University of Sydney. Professor Weiss said: "This is a superb, world class demonstration of leading Australian science. Our inventions are now giving us precise replicas of extraordinarily versatile, natural elastic proteins. By combining our research skills, we have developed a truly impressive technology that we hope will eventually be used to improve the way bone marrow is managed for better medical outcomes."

These findings could be good news for people who receive life-saving stem cell transplants (bone marrow and cord blood transplants) to treat diseased, damaged or faulty stem cells caused by various conditions or treatments such as leukaemia or chemotherapy.

Professor Rasko explained: "By increasing the number of stem cells we can grow outside of the body we could effectively use less bone marrow or cord blood to get the same result or use the same amount to get a much better result. For example, the small quantity of blood used from a cord blood donation often makes it suitable for small children only. Two cord blood donations are usually required to achieve safe transplants in older children or adults. However, in the future, we could use the blood from just one umbilical cord and then increase the number of stem cells to a viable level outside of the body before transplanting these life-saving cells into patients."


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Contact: Tanya Sarina
t.sarina@centenary.org.au
61-431-029-215
Centenary Institute
Source:Eurekalert

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