Navigation Links
Einstein researchers receive 2 Grand Challenges Explorations grants to combat HIV and TB
Date:12/4/2012

December 4, 2012 (Bronx, NY) Scientists at Albert Einstein College of Medicine of Yeshiva University have been awarded two Grand Challenges Explorations (GCE) grants from the Bill & Melinda Gates Foundation for their innovative global health and development research projects. The grant recipients are Arturo Casadevall, M.D., Ph.D., who is working to create a novel vaccine for tuberculosis (TB), and Ekaterina Dadachova, Ph.D., and Joan Berman, Ph.D., for their work on a novel and promising HIV treatment.

Dr. Casadevall, professor and chair of microbiology & immunology and professor of medicine, was named one of the 80 GCE Round 9 winners for his unconventional approach to developing a vaccine for TB. While current TB vaccines are designed to provoke immune cells to attack the bacteria that cause the disease, Dr. Casadevall proposes a different tack harnessing the tremendous potential of antibodies to kill the invaders and prevent the development of the disease. Dr. Dadachova, professor of radiology and of microbiology & immunology, and Dr. Berman, professor of pathology and of microbiology & immunology, received a Phase II GCE grant to study whether radioimmunotherapy (RIT) can kill the HIV virus in latently infected cells. In RIT, radioactive isotopes attached to antibodies selectively target and destroy cells. Since current anti-retroviral therapy drugs cannot reach the brain, they will also investigate whether the RIT approach can destroy HIV in the central nervous system. The project, which builds on Dr. Dadachova's earlier GCE research with Dr. Casadevall, is one of only 15 projects that advanced to the next level. Drs. Dadachova and Berman will work in collaboration with Dr. Casadevall, New York University researchers Susan Zolla-Pazner, Ph.D., and Miroslaw Gorny, M.D., Ph.D., and Alfred Morgenstern, Ph.D., and Frank Bruchertseifer, Ph.D., from the Institute of Transuranium Elements in Karlsruhe, Germany, who supply valuable radioisotopes for the project.

GCE funds researchers worldwide who are taking innovative approaches to some of the world's toughest and persistent global health and development challenges. GCE invests in the early stages of bold ideas that may help to solve the problems confronting people in the developing world every day.

"Investments in innovative global health research are already paying off," said Chris Wilson, director of Global Health Discovery and Translational Sciences at the Bill & Melinda Gates Foundation. "We continue to be impressed by the novelty and innovative spirit of Grand Challenges Explorations projects and are enthusiastic about this exciting research. These investments hold real potential to yield new solutions to improve the health of millions of people in the developing world, and ensure that everyone has the chance to live a healthy productive life."

Dr. Casadevall also holds the Leo and Julia Forchheimer Chair in Microbiology & Immunology and Dr. Dadachova is the Sylvia and Robert S. Olnick Faculty Scholar in Cancer Research.


'/>"/>

Contact: Kim Newman
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine
Source:Eurekalert

Related biology news :

1. Einstein researcher receives $10.8 million grant to study toxic blood reactions caused by hemoglobin
2. Einstein hosts its first stem cell institute symposium
3. Feinstein Institute receives $1 million grant to study impact of World Trade Center attacks on responders
4. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
5. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
6. Researchers attempt to solve problems of antibiotic resistance and bee deaths in one
7. UNH researchers find African farmers need better climate change data to improve farming practices
8. Ottawa researchers to lead world-first clinical trial of stem cell therapy for septic shock
9. Researchers uncover molecular pathway through which common yeast becomes fungal pathogen
10. Researchers print live cells with a standard inkjet printer
11. Columbia Engineering and Penn researchers increase speed of single-molecule measurements
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/20/2017)... , July 20, 2017 Delta (NYSE: DAL ... board any Delta aircraft at Reagan Washington National Airport (DCA). ... Delta launches biometrics to ... Delta,s biometric ... Sky Club is now integrated into the boarding process to allow ...
(Date:6/23/2017)... ARMONK, N.Y. and ITHACA, N.Y. ... IBM ) and Cornell University, a leader in dairy ... combined with bioinformatics designed to help reduce the chances ... breaches. With the onset of this dairy project, Cornell ... the Consortium for Sequencing the Food Supply Chain, a ...
(Date:5/23/2017)...  Hunova, the first robotic gym for the rehabilitation and functional motor ... Genoa, Italy . The first 30 robots will be ... USA . The technology was developed and patented at the ... spin-off Movendo Technology thanks to a 10 million euro investment from entrepreneur ... ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... launched Rosalind™, the first-ever genomics analysis platform specifically designed for life science ... in honor of pioneering researcher Rosalind Franklin, who made a major contribution ...
(Date:10/11/2017)... (PRWEB) , ... October 11, 2017 , ... ... pathology, announced today it will be hosting a Webinar titled, “Pathology is going ... Pathology Associates , on digital pathology adoption best practices and how Proscia improves ...
(Date:10/11/2017)... ... October 11, 2017 , ... Singh Biotechnology today announced that ... SBT-100, its novel anti-STAT3 (Signal Transducer and Activator of Transcription 3) B VHH13 ... cross the cell membrane and bind intracellular STAT3 and inhibit its function. Dysregulation ...
(Date:10/10/2017)... , Oct. 10, 2017 International research firm Parks ... Strategy, will speak at the TMA 2017 Annual Meeting , October ... trends in the residential home security market and how smart safety and ... Parks ... "The residential ...
Breaking Biology Technology: