Navigation Links
Einstein researchers develop a new way to study how breast cancer spreads
Date:11/12/2008

ntaining a small glass window onto the breast tumor of a mouse formed from cancerous cells that have a specific tag. Through the glass, individual breast tumor cells are targeted with a laser that 'marks' the cancer cells red. By viewing the cells through the window using a microscope, researchers can follow the cells as they spread. The mouse can move around and live normally with the glass plate and then be anesthetized briefly for observance under the microscope. The marked cancer cells are followed over a period of days until they lose their brightness.

Using this technique, investigators found that breast cancer cells closer to blood vessels were more aggressive and directed in their invasiveness than cancer cells farther from blood vessels. The cancer cells near blood vessels also appeared in the lung indicating that they are disseminated throughout the body.

As co-lead author, Bojana Gligorijevic Ph.D., explained, "Our work showed how important the microenvironment of a tumor is to the behavior of a cancer cell and the metastatic outcome of the tumor itself. We can now look at the early steps of metastasis in high resolution and specific regions of the tumor."

This finding marks the first time a direct link was shown between the presence of blood vessels and the invasive ability of a cancer cell, which strengthens the growing theory that blood supply is crucial to effective metastasis. It also suggests that many cancer therapies currently in development, which are directed at cutting off blood supply to tumors, may be on the right track.

The research was conducted by Dmitriy Kedrin, Bojana Gligorijevic, Ph.D. and team leader Jacco van Rheenen, Ph.D. under the direction of Drs. Segall and Condeelis. Vladislav Verkhusha, Ph.D., associate professor of anatomy and structural biology, and Jeffrey Wyckoff, M.F.A., B.S., senior associate of anatomy and structural biology, both members of the Biophotonics Center, contributed nove
'/>"/>

Contact: Michael Heller
mheller@aecom.yu.edu
718-430-3101
Albert Einstein College of Medicine
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Einstein researcher receives NIH grant to explore epigenetic regulation of the human genome
2. Einstein researchers receive grants totaling $700,000 for innovative breast cancer research
3. Feinstein researchers develop new genetic method and identify novel genes for schizophrenia
4. In scientific first, Einstein researchers correct decline in organ function associated with old age
5. Researchers identify proteins involved in new neurodegenerative syndrome
6. Texas researchers and educators head for Antarctica
7. MGH researchers describe new way to identify, evolve novel enzymes
8. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
9. U of MN researchers discover noninvasive diagnostic tool for brain diseases
10. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
11. Researchers discover new strategies for antibiotic resistance
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2015)... Research and Markets ( http://www.researchandmarkets.com/research/9dmm6l/global_biometric ) ... Biometric Authentication & Identification Market: Focus On Modality, ... report to their offering. ... is expected to grow at an estimated CAGR ... over $25 billion (approximately) by 2020 as per ...
(Date:8/12/2015)...  New research unveiled at Black Hat 2015 ... steal users, fingerprints. Information released today by HYPR ... on mobile devices, making the security of this ... mobile devices, HYPR Corp. recently released a biometric ... with strong cryptographic security. More information on this ...
(Date:8/10/2015)... , August 10, 2015 The latest ... offers comprehensive analysis of the global border security market ... revenues of $16.4bn in 2015. Now: Border security ... an example of the business critical issue you need to ... visiongain ,s objective analysis of how this will impact ...
Breaking Biology News(10 mins):Global Biometric Authentication & Identification Market 2015: Focus On Modality, Motility & Application - Estimation & Forecasts to 2020 for the $25 Billion Industry 2HYPR Corp. Addresses Android Vulnerability That Exposes Ecosystem-wide Biometric Security Challenges 2HYPR Corp. Addresses Android Vulnerability That Exposes Ecosystem-wide Biometric Security Challenges 3Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 2Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 3Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 4Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 5Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 6Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 7Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 8Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 9
... making some of our immune proteins into the inflammatory defenders ... will appear in the June 8 issue of the ... conducted by a team of researchers in Italy, also suggests ... genes into risk factors for intestinal disorders. Parasite-driven ...
... Council (BBSRC) could lead to the development of new ... problems associated with ageing. Nearly 4M has been ... College London, Nottingham and Southampton and who will work ... look at the development and repair of human skeletal ...
... Medicine (MDC) Berlin-Buch, Germany, have gained crucial insight into ... sensory neurons of mice, the neurobiologists and pain researchers ... able to directly elucidate, for the first time, the ... able to show that neurons develop their sensitivity to ...
Cached Biology News:Immune genes adapt to parasites 2Award for pioneering stem cell research to mend broken bones 2Investigating the development of mechanosensitivity 2
(Date:8/28/2015)... ... August 28, 2015 , ... ... has organized and will present a session on chemical spectroscopic imaging at JASIS ... and exposition is Asia’s largest analytical and scientific instruments show which will be ...
(Date:8/27/2015)... Reston, VA (PRWEB) , ... August 27, 2015 , ... ... government contractors solve complex business problems, is pleased to announce their ranking as one ... 34th annual ranking of the fastest-growing private companies across the nation. , “It is ...
(Date:8/27/2015)... 27, 2015 /PRNewswire/ - BIOREM Inc. (TSXV: BRM) ("Biorem" or "the ... ended June 30, 2015. Biorem,s complete second quarter financial statements and ... FINANCIAL HIGHLIGHTS: in ,000,s except earnings per shareThree-months ended , Six -months ... , 2015 , 2014 Revenue , 4,709 ... 4,433 Gross profit , 1,656 , 56 ...
(Date:8/27/2015)... 27, 2015 In response to recent ... and The US Postal Service to no longer ... ,select agents, by the CDC, Marken reaffirmed today ... sensitive shipments. Marken uses its flexible ... and certified personnel to ensure the safe and ...
Breaking Biology Technology:U.S. Symposium on Imaging Organized by Pittcon’s Program Chairman Chuck Gardner 2U.S. Symposium on Imaging Organized by Pittcon’s Program Chairman Chuck Gardner 3Capital Edge Consulting Makes Inc. 5000 List of America’s Fastest-Growing Private Companies 2Capital Edge Consulting Makes Inc. 5000 List of America’s Fastest-Growing Private Companies 3BIOREM Reports $718,000 Net Earnings for the Second Quarter 2BIOREM Reports $718,000 Net Earnings for the Second Quarter 3Marken Ensures Safe Transportation Of Select Agents And Toxins 2
... 2011 GeneLink, Inc. ( OTCBB: GNLK ... biotech company, is pleased to report that by Order ... denied the Petition for Allowance of Appeal filed by ... his wife against the Company, its subsidiary GeneWize Life ...
... Blood America, Inc . ( http://www.cordblood-america.com ) (OTC Bulletin Board: ... cell preservation company focused on bringing the life saving ... pleased to announce that the Pinellas County Circuit Court granted ... against Cord Blood America, which CBAI management believed was an ...
... With the first observation of thermoelectric effects at graphene ... have a nanoscale cooling effect that reduces their temperature. ... King and electrical and computer engineering professor Eric Pop, ... 3 advance online edition of the journal Nature ...
Cached Biology Technology:Cord Blood America: Court Grants Motion to Dismiss at Lawsuit Aimed at Blocking Acquisition 2Self-cooling observed in graphene electronics 2
... LabX pro balance increases your lab productivity and ... quality and regulatory compliance. Move ahead beyond traditional ... networked data system. *Instruments supported: ... AX, MX, UMX, AG, XS, XP, PR, SR, ...
XPLAC (S-17)...
High affinity antibody reacting with S-100 ab heterodimer. Could be used for Western blotting application and immunoassay....
... AAIPharmas Biotech Solutions Group combines deep ... with special qualities of collaborative team chemistry. ... from concept to approval and beyond.,With AAIBiotech, ... capabilities. But you get more than that: ...
Biology Products: